Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katherine Najera"'
Autor:
Emily F. Mendez, Sandra L. Grimm, Laura Stertz, Damian Gorski, Sai V. Movva, Katherine Najera, Karla Moriel, Thomas D. Meyer, Gabriel R. Fries, Cristian Coarfa, Consuelo Walss-Bass
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionHuman-derived induced pluripotent stem cell (iPSC) models of brain promise to advance our understanding of neurotoxic consequences of drug use. However, how well these models recapitulate the actual genomic landscape and cell function, as
Externí odkaz:
https://doaj.org/article/e69ef664aef746999f9747cf0a007401
Autor:
Bharathi S. Gadad, Javier Vargas-Medrano, Enrique Ivan Ramos, Katherine Najera, Matthew Fagan, Angelica Forero, Peter M. Thompson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Interleukins and neurotrophins levels are altered in the periphery of patients with major depression and suicidal behavior, however it is not clear if similar abnormalities occur in the central nervous system. Our objective was to examine th
Externí odkaz:
https://doaj.org/article/025b9a5ebc4b4ad59d5209744bd17813
Autor:
Zhongming Zhao, Shan Jiang, Gabriel Rodrigo Fries, Consuelo Walss-Bass, Yulin Dai, Thomas Meyer, Ruifeng Hu, Emily Mendez, Andi Liu, Peilin Jia, Katherine Najera, Laura Stertz
Publikováno v:
International Journal of Neuropsychopharmacology
Background Opioid use disorder (OUD) affects millions of people, causing nearly 50 000 deaths annually in the United States. While opioid exposure and OUD are known to cause widespread transcriptomic and epigenetic changes, few studies in human sampl
Autor:
Brenda Cabrera‐Mendoza, Laura Stertz, Katherine Najera, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas D. Meyer, Gabriel R. Fries, Consuelo Walss‐Bass
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsREFERENCES.
There is a possible accelerated biological aging in patients with substance use disorders (SUD). The evaluation of epigenetic clocks, which are accurate estimators of biological aging based on DNA methylation changes, has been limited to blood tissue
Autor:
Ruth G. Perez, Valeria Diaz-Pacheco, Julie D. Miranda, Barbara Yang, Katherine Najera, Guadalupe Vidal-Martinez, Javier Vargas-Medrano, Carolina Gil-Tommee
Publikováno v:
Neuroscience
Parkinson's disease (PD) is a progressive aging disorder that affects millions worldwide, thus, disease-modifying-therapies are urgently needed. PD pathology includes α-synuclein (aSyn) accumulation as synucleinopathy. Loss of GM1 gangliosides occur
Autor:
Brenda Cabrera Mendoza, Laura Stertz, Katherine Najera, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas Meyer, Consuelo Walss Bass, Gabriel Fries
Publikováno v:
Biological Psychiatry. 91:S95
Autor:
Gabriel Rodrigo Fries, Emily Mendez, Junqian Xu, Zhongming Zhao, Sudhakar Selvaraj, Jia Qian Wu, Joo Won Kim, Thomas Meyer, Katherine Najera, Xizi Wu, Consuelo Walss-Bass, Laura Stertz, Christie M. Lincoln, Haichao Wei, Ruifeng Hu, Antônio Lúcio Teixeira, Karla Moriel, Michael D Monterey
Publikováno v:
Molecular psychiatry. 26(12)
Opioid use disorder (OUD) is a public health crisis in the U.S. that causes over 50 thousand deaths annually due to overdose. Using next-generation RNA sequencing and proteomics techniques, we identified 394 differentially expressed (DE) coding and l
Autor:
Angelica Forero, Peter M. Thompson, Bharathi S. Gadad, Matthew Fagan, Katherine Najera, Enrique I Ramos, Javier Vargas-Medrano
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Interleukins and neurotrophins levels are altered in the periphery of patients with major depression and suicidal behavior, however it is not clear if similar abnormalities occur in the central nervous system. Our objective was to examine the associa
Autor:
Zhongming Zhao, Thomas Meyer, Haichao Wei, Karla Moriel, Jia Qian Wu, Xizi Wu, Emily Mendez, Gabriel Rodrigo Fries, Katherine Najera, Consuelo Walss-Bass, Laura Stertz, Ruifeng Hu
Publikováno v:
Biological Psychiatry. 89:S317-S318
Publikováno v:
Neuroscience. 420
Synaptosomal Associated Protein-25 kilodaltons (SNAP-25) is an integral member of the SNARE complex. This complex is essential for calcium-triggered synaptic vesicular fusion and release of neurotransmitters into the synaptic cleft. In addition to ne