Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Katherine McJunkin"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 3, Pp 901-909 (2019)
The germline sex determination pathway in C. elegans determines whether germ cells develop as oocytes or sperm, with no previously known effect on viability. The mir-35 family of microRNAs are expressed in the C. elegans germline and embryo and are e
Externí odkaz:
https://doaj.org/article/67af37268792485d812d0b7ae143e26c
Autor:
Gregory M Davis, Shikui Tu, Joshua WT Anderson, Rhys N Colson, Menachem J Gunzburg, Michelle A Francisco, Debashish Ray, Sean P Shrubsole, Julia A Sobotka, Uri Seroussi, Robert X Lao, Tuhin Maity, Monica Z Wu, Katherine McJunkin, Quaid D Morris, Timothy R Hughes, Jacqueline A Wilce, Julie M Claycomb, Zhiping Weng, Peter R Boag
Publikováno v:
eLife, Vol 7 (2018)
Proper regulation of germline gene expression is essential for fertility and maintaining species integrity. In the C. elegans germline, a diverse repertoire of regulatory pathways promote the expression of endogenous germline genes and limit the expr
Externí odkaz:
https://doaj.org/article/02c779641e7847d38284aedcaf454370
Autor:
Guillaume Jannot, Pascale Michaud, Miguel Quévillon Huberdeau, Louis Morel-Berryman, James A Brackbill, Sandra Piquet, Katherine McJunkin, Kotaro Nakanishi, Martin J Simard
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006484 (2016)
MicroRNAs and Argonaute form the microRNA induced silencing complex or miRISC that recruits GW182, causing mRNA degradation and/or translational repression. Despite the clear conservation and molecular significance, it is unknown if miRISC-GW182 inte
Externí odkaz:
https://doaj.org/article/2c218caaad5344c49c9657cd210f4b08
Autor:
Guillaume Jannot, Pascale Michaud, Miguel Quévillon Huberdeau, Louis Morel-Berryman, James A Brackbill, Sandra Piquet, Katherine McJunkin, Kotaro Nakanishi, Martin J Simard
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006534 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1006484.].
Externí odkaz:
https://doaj.org/article/f558e6522c3741bea09bccd2bf1c0da4
Autor:
Kasuen Kotagama, Katherine McJunkin
Publikováno v:
Seminars in Cell & Developmental Biology.
Autor:
Kasuen Kotagama, Acadia L. Grimme, Bing Yang, Rima M. Sakhawala, Guoyun Yu, Katherine McJunkin
Publikováno v:
bioRxiv
Many Argonaute proteins can cleave RNA (“slicing”) as part of the microRNA-induced silencing complex (miRISC), even though miRNA-mediated target repression is generally independent of target cleavage. Here we useC. elegansto examine the role of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3f29feb7ee640ea795e791898b6e93
https://europepmc.org/articles/PMC9882359/
https://europepmc.org/articles/PMC9882359/
Publikováno v:
Genes & Development. 34:1227-1238
Identifying miRNA target genes is difficult, and delineating which targets are the most biologically important is even more difficult. We devised a novel strategy to test the phenotypic impact of individual microRNA–target interactions by disruptin
Autor:
Bing Yang, Katherine McJunkin
Publikováno v:
The FEBS Journal. 287:2914-2922
Identifying microRNA (miRNA) target genes remains a major challenge in understanding the roles miRNAs play in gene regulation. Furthermore, understanding which miRNA-target interactions are the most biologically important is even more difficult. We p
Publikováno v:
Genes Dev
Identifying miRNA target genes is difficult, and delineating which targets are the most biologically important is even more difficult. We devised a novel strategy to test the phenotypic impact of individual microRNA–target interactions by disruptin
Autor:
Bridget F. Donnelly, Bing Yang, Acadia L. Grimme, Karl-Frédéric Vieux, Chen-Yu Liu, Lecong Zhou, Katherine McJunkin
MicroRNA (miRNA) abundance is tightly controlled by regulation of biogenesis and decay. Here we show that the mir-35 miRNA family undergoes selective decay at the transition from embryonic to larval development in C. elegans. The seed sequence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f70ea246f36c042804648a82e9884c
https://doi.org/10.1101/2021.11.19.469346
https://doi.org/10.1101/2021.11.19.469346