Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katherine M. Schlitt"'
Autor:
Lex Navarro-Whyte, Richard A. Manderville, Andrea L. Millen, Robert J. Paugh, Katherine M. Schlitt, Stacey D. Wetmore, Kewen M. Sun
Publikováno v:
The Journal of Organic Chemistry. 74:5793-5802
Direct addition of aryl radical species to the C(8)-site of 2'-deoxyguanosine (dG) affords C(8)-aryl-dG adducts that are produced by carcinogenic arylhydrazines, polycyclic aromatic hydrocarbons (PAHs), and certain phenolic toxins. A common property
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f650a4cc41a7d40671b4a04024ef5b31
https://doi.org/10.1021/jo901080w
https://doi.org/10.1021/jo901080w
Fluorescent C-linked C8-aryl-guanine probe for distinguishing syn from anti structures in duplex DNA
Autor:
Andrea L. Millen, Katie A. Wilson, Richard A. Manderville, Katherine M. Schlitt, Alireza Omumi, Stacey D. Wetmore
Publikováno v:
Chemical research in toxicology. 25(6)
The synthesis and optical properties of the carbon (C)-linked C(8)-(2"-benzo[b]thienyl)-2'-deoxyguanosine ((Bth)dG), which acts as a fluorescent reporter of syn versus anti glycosidic conformations in duplex DNA, are described. In the syn-conformatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b998529ee0847807e0cb91cbf9c07e3
https://pubmed.ncbi.nlm.nih.gov/22667322
https://pubmed.ncbi.nlm.nih.gov/22667322
Publikováno v:
Organic & Biomolecular Chemistry. 9:1565
Pyrrole- and indole-linked C(8)-deoxyguanosine nucleosides act as fluorescent reporters of H-bonding specificity. Their fluorescence is quenched upon Watson-Crick H-bonding to dC, while Hoogsteen H-bonding to G enhances emission intensity. The indole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716083698611b665e6ac3ba41797a45f
https://doi.org/10.1039/c0ob00883d
https://doi.org/10.1039/c0ob00883d