Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katherine M. Ellis"'
Autor:
Madeline R. Luth, Fernando Sánchez-Román Terán, Jake Baum, Ursula Straschil, Michael D. Edstein, Michael J. Delves, Leonardo Lucantoni, Elizabeth A. Winzeler, Stuart A. Ralph, Katherine M. Ellis, Marina Chavchich, Jonathan B. Baell, Darren J. Creek, Clemens H. M. Kocken, Amanda De Paoli, Vicky M. Avery, Anne-Marie Zeeman, Matthew Abraham
Publikováno v:
Antimicrob Agents Chemother
Novel bis-1,2,4-triazine compounds with potent in vitro activity against Plasmodium falciparum parasites were recently identified. The bis-1,2,4-triazines represent a unique antimalarial pharmacophore and are proposed to act by a novel but as-yet-unk
Autor:
Sandra Duffy, Marina Chavchich, Grennady Wirjanata, Silvia Teguh, Susan A. Charman, Rintis Noviyanti, Jitendra R. Harjani, Leonardo Lucantoni, Lian Xue, Jutta Marfurt, Michael D. Edstein, Ric N. Price, Tamir Dingjan, Stuart A. Ralph, Julia G. Beveridge, Michael A. Walters, Katherine M. Ellis, Scott Blundell, Jonathan B. Baell, Darren J. Creek, Fei Huang, Sabine Fletcher, Sarah Diab, Vicky M. Avery, Jayme L. Dahlin, Francis C. K. Chiu, Kung Ban, Jessica M. Strasser, Matthew E. Cuellar, Da Hua Shi
Publikováno v:
Journal of Medicinal Chemistry. 62(5)
A series of 3,3′-disubstituted 5,5′-bi(1,2,4-triazine) derivatives was synthesized and screened against the erythrocytic stage of Plasmodium falciparum 3D7 line. The most potent dimer, 6k, with an IC50 (50% inhibitory concentration) of 0.008 μM,
Publikováno v:
Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2057647e87b30ba85adbf1afa7faac68
https://doi.org/10.1002/9783527694082.ch14
https://doi.org/10.1002/9783527694082.ch14
Autor:
Amy J. Jones, Katherine M. Ellis, Jennifer Riley, Malcolm J. McConville, Vicky M. Avery, Daniel Stoessel, Cameron J. Nowell, Raphaël Rahmani, Lori Ferrins, Kevin D. Read, Jonathan B. Baell, Darren J. Creek
Publikováno v:
Metabolomics. 12
Trypanosoma brucei is the causative agent of human African trypanosomiasis, which is responsible for thousands of deaths every year. Current therapies are limited and there is an urgent need to develop new drugs. The anti-trypanosomal compound, 3-(ox
Publikováno v:
Analytical Chemistry. 51:942-947
An instrumental neutron activation analysis (INAA) method has been developed for the simultaneous multielement determinations in samples of estuarine suspended particulate matter (SPM) weighing between 0.75 and 7.5 mg. The INAA method consists of fou