Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katherine M. Digianantonio"'
Publikováno v:
Nature Chemical Biology. 14:253-255
Producing novel enzymes that are catalytically active in vitro and biologically functional in vivo is a key goal of synthetic biology. Here we describe Syn-F4, the first de novo protein that meets both criteria. Purified Syn-F4 hydrolyzes the siderop
Publikováno v:
Proceedings of the National Academy of Sciences. 113:2400-2405
Recent advances in protein design rely on rational and computational approaches to create novel sequences that fold and function. In contrast, natural systems selected functional proteins without any design a priori. In an attempt to mimic nature, we
Publikováno v:
The Journal of Organic Chemistry. 77:2285-2298
Two-dimensional π-systems are of current interest in the design of functional organic molecules, exhibiting unique behavior for applications in organic electronics, single-molecule devices, and sensing. Here we describe the synthesis and characteriz
Publikováno v:
Organicbiomolecular chemistry. 9(11)
N,N-dialkoxyamides 1c, a virtually unstudied member of the new class of anomeric amides, amides bearing two electronegative atoms at nitrogen, have been synthesised in useful yields directly from hydroxamic esters using phenyliodine(III)bis(trifluoro