Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Katherine M Young"'
Autor:
Samantha C Schwager, Katherine M Young, Lauren A Hapach, Caroline M Carlson, Jenna A Mosier, Tanner J McArdle, Wenjun Wang, Curtis Schunk, Anissa L Jayathilake, Madison E Bates, Francois Bordeleau, Marc A Antonyak, Richard A Cerione, Cynthia A Reinhart-King
Publikováno v:
eLife, Vol 11 (2022)
Cancer cell migration is highly heterogeneous, and the migratory capability of cancer cells is thought to be an indicator of metastatic potential. It is becoming clear that a cancer cell does not have to be inherently migratory to metastasize, with w
Externí odkaz:
https://doaj.org/article/622c88bf6fa14684a1a8c69fe64f0098
Autor:
Tom Bongiorno, Jeremy Gura, Priyanka Talwar, Dwight Chambers, Katherine M Young, Dalia Arafat, Gonghao Wang, Emily L Jackson-Holmes, Peng Qiu, Todd C McDevitt, Todd Sulchek
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192631 (2018)
The highly proliferative and pluripotent characteristics of embryonic stem cells engender great promise for tissue engineering and regenerative medicine, but the rapid identification and isolation of target cell phenotypes remains challenging. Theref
Externí odkaz:
https://doaj.org/article/034f79755c7847a6b504cfe8c3fc2379
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82779 (2013)
Understanding the link between vaccine immunogenicity and efficacy is currently a major focus in HIV research. Consequently, recent developments in the HIV-1 vaccine field have led to a closer look at immune responses to known efficacious vaccines. W
Externí odkaz:
https://doaj.org/article/a0f507a22b504b0490888d852ad0f93e
Cancer-associated fibroblasts in early-stage lung adenocarcinoma correlate with tumor aggressiveness
Autor:
Georgii Vasiukov, Yong Zou, Maria-Fernanda Senosain, Jamshedur S. M. Rahman, Sanja Antic, Katherine M. Young, Eric L. Grogan, Michael N. Kammer, Fabien Maldonado, Cynthia A. Reinhart-King, Pierre P. Massion
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Lung adenocarcinoma (LUAD) is the predominant type of lung cancer in the U.S. and exhibits a broad variety of behaviors ranging from indolent to aggressive. Identification of the biological determinants of LUAD behavior at early stages can i
Externí odkaz:
https://doaj.org/article/0aa600558c58426ca5beeb5b7def2354
Autor:
Katherine M. Young, Congmin Xu, Kelly Ahkee, Roman Mezencev, Steven P. Swingle, Tong Yu, Ava Paikeday, Cathy Kim, John F. McDonald, Peng Qiu, Todd Sulchek
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106393- (2023)
Summary: Stiffness has been observed to decrease for many cancer cell types as their metastatic potential increases. Although cell mechanics and metastatic potential are related, the underlying molecular factors associated with these phenotypes remai
Externí odkaz:
https://doaj.org/article/7238bcfdd70848a69389f7f2299c37ba
Autor:
Alexander Alexeev, A. Raj, Peter G. Shankles, Fatima Ezahra Chrit, Kesiharjun Lokireddy, Todd Sulchek, Christopher R. Flowers, Katherine M. Young, Nicholas Stone, Edmund K. Waller
Publikováno v:
ACS Sensors. 6:3789-3799
Mechanical properties of cells such as stiffness can act as biomarkers to sort or detect cell functional properties such as viability. In this study, we report the use of a microfluidic device as a high-sensitivity sensor that transduces cell biomech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ac7f697f707fb0a628268049637533
https://doi.org/10.1021/acssensors.1c01770
https://doi.org/10.1021/acssensors.1c01770
Autor:
A. Raj, Katherine M. Young, Benedict B. Benigno, Todd Sulchek, Alexander Alexeev, Budd A. Tucker, Nicholas Stone, Adam P. DeLuca, Fatima Ezahra Chrit, John F. McDonald
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The isolation of a patient's metastatic cancer cells is the first, enabling step toward treatment of that patient using modern personalized medicine techniques. Whereas traditional standard-of-care approaches select treatments for cancer patients bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb7b0c686b40f54afaada7e93d4d0f5
https://doaj.org/article/0613c178092047e293ef608a8167e235
https://doaj.org/article/0613c178092047e293ef608a8167e235
Autor:
Samantha C Schwager, Katherine M Young, Lauren A Hapach, Caroline M Carlson, Jenna A Mosier, Tanner J McArdle, Wenjun Wang, Curtis Schunk, Anissa L Jayathilake, Madison E Bates, Francois Bordeleau, Marc A Antonyak, Richard A Cerione, Cynthia A Reinhart-King
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e85f5010046c57f785936901cc66465
https://doi.org/10.7554/elife.74433.sa2
https://doi.org/10.7554/elife.74433.sa2
Strain-dependent elastography of cancer cells reveals heterogeneity and stiffening due to attachment
Publikováno v:
Journal of Biomechanics. 150:111479
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c78ce219f6b2b5f600833b55d130691
https://doi.org/10.1016/j.jbiomech.2023.111479
https://doi.org/10.1016/j.jbiomech.2023.111479
Publikováno v:
Biomicrofluidics
Microfluidics can bring unique functionalities to cell processing, but the small channel dimensions often limit the throughput for cell processing that prevents scaling necessary for key applications. While processing throughput can be improved by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335baa92a6781535177db30e245e382b
https://pubmed.ncbi.nlm.nih.gov/35600502
https://pubmed.ncbi.nlm.nih.gov/35600502