Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katherine Loomis"'
Publikováno v:
The American Journal of Occupational Therapy. 76:7610505027p1-7610505027p1
Date Presented 03/31/2022 This multimethod study identified four themes within the therapist-patient relationship that affect the provision of holistic and collaborative care. Therapists developed a complex relationship with their patients, leading t
Publikováno v:
Open Forum Infectious Diseases
Acinetobacter baumannii has among the highest rates of antibiotic resistance encountered in hospitals. New therapies are critically needed. We found that rifabutin has previously unrecognized hyperactivity against most strains of A. baumannii. Here w
Publikováno v:
Open Forum Infectious Diseases
Background A challenging feature in those with opioid use disorder-associated infective endocarditis (OUD-IE) is the duration and route of treatment, which often requires long inpatient stays. Those with OUD-IE often experience opioid withdrawal in t
Publikováno v:
Chest. 158:A250
Autor:
Katherine Loomis, Kevin Daniel Freeman-Cook, Zhengrong Zhao, Susan Tapley, Dennis Paul Phillion, Richard L. Elliott, Steven B. Coffey, Christopher S. Jones, Kevin E. Henegar, Kirk McPherson, Chris Limberakis, Scott Bader, Janet A. Houser, Leanne M. Buzon, Angel Guzman-Perez, Shawn D. Doran, Wei Song, Betsy Pierce, Kendra Louise Nelson, Meihua Tu, William P. Esler, Kenneth J. DiRico, Sharad B. Murdande, Jeffrey W. Corbett, Paul A. Amor, Eliot Sugarman
Publikováno v:
Journal of medicinal chemistry. 55(2)
This paper describes the design and synthesis of a novel series of dual inhibitors of acetyl-CoA carboxylase 1 and 2 (ACC1 and ACC2). Key findings include the discovery of an initial lead that was modestly potent and subsequent medicinal chemistry op