Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Katherine Labbé"'
Autor:
Katherine Labbé, Lauren LeBon, Bryan King, Ngoc Vu, Emily H. Stoops, Nina Ly, Austin E. Y. T. Lefebvre, Phillip Seitzer, Swathi Krishnan, Jin-Mi Heo, Bryson Bennett, Carmela Sidrauski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The integrated stress response (ISR) enables cells to cope with a variety of insults, but its specific contribution to downstream cellular outputs remains unclear. Using a synthetic tool, we selectively activate the ISR without co-activation
Externí odkaz:
https://doaj.org/article/27e86f13e45248efb23da08ad179a50a
Autor:
Jodi Nunnari, Chad Lerner, Shona A. Mookerjee, Eddy Gibbs, Katherine Labbé, Maxence Le Vasseur
Publikováno v:
The Journal of cell biology. 220(11)
Mitochondrial function is integrated with cellular status through the regulation of opposing mitochondrial fusion and division events. Here we uncover a link between mitochondrial dynamics and lipid metabolism by examining the cellular role of mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e74a084783c8db6babf44b80b45fdc
https://pubmed.ncbi.nlm.nih.gov/34586346
https://pubmed.ncbi.nlm.nih.gov/34586346
Autor:
Ashanti O. Matlock, Jane E. Jackman, Avraham Shaag, Katherine Labbé, Krishna J. Patel, Chaim Jalas, Yael Elbaz-Alon, Orly Elpeleg, Simon Edvardson
Publikováno v:
neurogenetics. 17:219-225
Autosomal-recessive cerebellar atrophy is usually associated with inactivating mutations and early-onset presentation. The underlying molecular diagnosis suggests the involvement of neuronal survival pathways, but many mechanisms are still lacking an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9605ea0d1f73f6191897c190e442cc89
https://doi.org/10.1007/s10048-016-0487-z
https://doi.org/10.1007/s10048-016-0487-z
Autor:
Maya Saleh, Katherine Labbé
Publikováno v:
Cell Death & Differentiation. 15:1339-1349
Infections elicit diverse responses in the host that include activation of the innate immune system, inflammation and cell death. Pathogen-triggered cell death is manifested by various morphologies indicative of apoptosis, pyroptosis, oncosis or auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ae5239c1afb6d48cd716e9ce214ca2
https://doi.org/10.1038/cdd.2008.91
https://doi.org/10.1038/cdd.2008.91
Autor:
Jacopo P. Mortola, Katherine Labbé
Publikováno v:
Respiratory Physiology & Neurobiology. 146:97-106
We measured the effects of hypoxia and changes in ambient temperature (T) on the oxygen consumption (VO2) of chicken embryos at embryonic days 11, 16 and 20 (E11, E16 and E20, respectively), and post-hatching day 1 (H1). Between 30 and 39 degrees C,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8463c45002844fe75f47cec7c16adb
https://doi.org/10.1016/j.resp.2004.10.011
https://doi.org/10.1016/j.resp.2004.10.011
Publikováno v:
Annual review of cell and developmental biology. 30
Mitochondria are ancient organelles evolved from bacteria. Over the course of evolution, the behavior of mitochondria inside eukaryotic cells has changed dramatically, and the corresponding machineries that control it are in most cases new inventions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e534a1de7978c27fa99b5595730437
https://pubmed.ncbi.nlm.nih.gov/25288115
https://pubmed.ncbi.nlm.nih.gov/25288115
Autor:
Maya Saleh, Katherine Labbé
Publikováno v:
The Inflammasomes ISBN: 9783034801478
Infection elicits a number of innate protective responses in the host that cooperate to promote effective pathogen clearance. Increasingly, the inflammatory response to infection appears to be coupled to cell death as an important mediator of host de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4fe28fbd44a7eb77b0cfbbb1122237
https://doi.org/10.1007/978-3-0348-0148-5_2
https://doi.org/10.1007/978-3-0348-0148-5_2
Autor:
Kevin C. Kain, Constance A. M. Finney, Katherine Labbé, Mary M. Stevenson, Garabet Yeretssian, Mifong Tam, Maya Saleh, Laura K. Erdman, Marie-Line Goulet, Jenny Miu, Lena Serghides
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(9)
Pathogen sensing by the inflammasome activates inflammatory caspases that mediate inflammation and cell death. Caspase-12 antagonizes the inflammasome and NF-κB and is associated with susceptibility to bacterial sepsis. A single-nucleotide polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b12de3951f86220b87d2faa44b2909c
https://pubmed.ncbi.nlm.nih.gov/20876354
https://pubmed.ncbi.nlm.nih.gov/20876354
Autor:
Mathieu J.M. Bertrand, Karine Doiron, Maya Saleh, Robert G. Korneluk, Philip A. Barker, Katherine Labbé
Publikováno v:
Immunity. 30(6)
Summary Cellular inhibitor of apoptosis proteins (cIAPs) block apoptosis, but their physiological functions are still under investigation. Here, we report that cIAP1 and cIAP2 are E3 ubiquitin ligases that are required for receptor-interacting protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb6bb044b80e38234507a9d9fd673bf
https://pubmed.ncbi.nlm.nih.gov/19538923
https://pubmed.ncbi.nlm.nih.gov/19538923
Publikováno v:
Cytokine. 43(3)
Cell death and innate immunity are ancient evolutionary conserved processes that utilize a dazzling number of related molecular effectors and parallel signal transduction mechanisms. The investigation of the molecular mechanisms linking the sensing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e561767857e55ff2e27839173200727e
https://pubmed.ncbi.nlm.nih.gov/18703350
https://pubmed.ncbi.nlm.nih.gov/18703350