Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Katherine L. Wozniak"'
Autor:
Katherine L Wozniak, Rachel E Bainbridge, Dominique W Summerville, Maiwase Tembo, Wesley A Phelps, Monica L Sauer, Bennett W Wisner, Madelyn E Czekalski, Srikavya Pasumarthy, Meghan L Hanson, Melania B Linderman, Catherine H Luu, Madison E Boehm, Steven M Sanders, Katherine M Buckley, Daniel J Bain, Matthew L Nicotra, Miler T Lee, Anne E Carlson
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000811 (2020)
One of the earliest and most prevalent barriers to successful reproduction is polyspermy, or fertilization of an egg by multiple sperm. To prevent these supernumerary fertilizations, eggs have evolved multiple mechanisms. It has recently been propose
Externí odkaz:
https://doaj.org/article/6771199b97944637b30c134bee8471cc
Autor:
Naresh Pandey, Steffi A. Davison, Malathy Krishnamurthy, Daniel S. Trettel, Chien-Chi Lo, Shawn Starkenburg, Katherine L. Wozniak, Theresa L. Kern, Sean D. Reardon, Clifford J. Unkefer, Scott P. Hennelly, Taraka Dale
Publikováno v:
ACS synthetic biology. 11(10)
Engineered microbes can be used for producing value-added chemicals from renewable feedstocks, relieving the dependency on nonrenewable resources such as petroleum. These microbes often are composed of synthetic metabolic pathways; however, one major
Autor:
Katherine L Wozniak, Brianna L Mayfield, Alexis M Duray, Maiwase Tembo, David O Beleny, Marc A Napolitano, Monica L Sauer, Bennett W Wisner, Anne E Carlson
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170405 (2017)
The necessity of extracellular Ca2+ for fertilization and early embryonic development in the African clawed frog, Xenopus laevis, is controversial. Ca2+ entry into X. laevis sperm is reportedly required for the acrosome reaction, yet fertilization an
Externí odkaz:
https://doaj.org/article/e57348997b6245208ce334e7f6050903
Autor:
Monica L. Sauer, Miler T. Lee, Madelyn E. Czekalski, Rachel E. Bainbridge, Anne E. Carlson, Steven M. Sanders, Bennett W. Wisner, Wesley A. Phelps, Melania B. Linderman, Daniel J. Bain, Maiwase Tembo, Dominique W. Summerville, Srikavya Pasumarthy, Catherine H. Luu, Madison E. Boehm, Katherine M. Buckley, Matthew L. Nicotra, Katherine L. Wozniak, Meghan L. Hanson
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000811 (2020)
PLoS Biology
PLoS Biology
One of the earliest and most prevalent barriers to successful reproduction is polyspermy, or fertilization of an egg by multiple sperm. To prevent these supernumerary fertilizations, eggs have evolved multiple mechanisms. It has recently been propose
Publikováno v:
The Journal of General Physiology
The fast block to polyspermy is achieved in Xenopus laevis eggs by fertilization-induced depolarization. Wozniak et al. show that fertilization activates a signaling cascade involving phospholipase C, IP3, and intracellular Ca2+ release, which induce
Publikováno v:
J Biol Chem
Transmembrane member 16A (TMEM16A) is a widely expressed Ca(2+)-activated Cl(−) channel with various physiological functions ranging from mucosal secretion to regulating smooth muscle contraction. Understanding how TMEM16A controls these physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3d98a93a33535dbc1fa21049a3d588
https://europepmc.org/articles/PMC6699839/
https://europepmc.org/articles/PMC6699839/
Autor:
Anne E. Carlson, Katherine L. Wozniak
Publikováno v:
Mol Reprod Dev
Fertilization of an egg by multiple sperms, polyspermy, is lethal to most sexually reproducing species. To combat the entry of additional sperm into already fertilized eggs, organisms have developed various polyspermy blocks. One such barrier, the fa
Autor:
Anna M. Seekatz, Ingrid L. Bergin, Caitlyn T. Molloy, Katherine L. Wozniak, Casey M. Theriot, Vincent B. Young
Publikováno v:
Infection and Immunity. 83:3838-3846
Recurrent Clostridium difficile infection (CDI) is of particular concern among health care-associated infections. The role of the microbiota in disease recovery is apparent given the success of fecal microbiota transplantation (FMT) for recurrent CDI
Autor:
Wesley A. Phelps, Matthew L. Nicotra, Miler T. Lee, Steven M. Sanders, Katherine L. Wozniak, Anne E. Carlson, Rachel E. Bainbridge
Publikováno v:
Biophysical Journal. 118:563a
Publikováno v:
The Journal of General Physiology
In their preceding paper, Wozniak et al. show that fertilization increases intracellular Ca2+ in Xenopus laevis eggs by activating an IP3 signaling cascade. Here, they reveal that Ca2+ subsequently opens the Cl− channel TMEM16A to allow Cl− efflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce065e8e5b18bd0922c7fe306845dea
https://doi.org/10.1101/270629
https://doi.org/10.1101/270629