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pro vyhledávání: '"Katherine L. Petrie"'
Autor:
Katherine L. Petrie
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Support for undergraduate laboratory education based on a CURE (Course-based Undergraduate Research Experience) model is more widespread than ever. By giving students the opportunity to conduct genuine research in laboratory courses they are required
Externí odkaz:
https://doaj.org/article/7b932246c8cf4a2aa9dec29603de9adc
Autor:
Katherine L. Petrie, Stephanie J. Spielman, Debora S. Marks, Rohan Maddamsetti, Daniel T Johnson, Justin R. Meyer
Publikováno v:
Evolution; International Journal of Organic Evolution
Evolution
Evolution
Viral gain‐of‐function mutations frequently evolve during laboratory experiments. Whether the specific mutations that evolve in the lab also evolve in nature and whether they have the same impact on evolution in the real world is unknown. We stud
Autor:
Daniel T Johnson, Sarah J. Medina, Stephanie J. Yan, Justin R. Meyer, Nathan David Palmer, Victor Li, Alita R. Burmeister, Katherine L. Petrie
Publikováno v:
Science. 359:1542-1545
Nongenetic variation drives viral evolution Bacteriophage λ is a virus that infects bacteria by exploiting various membrane proteins in a well-characterized manner. Petrie et al. show how the evolution of variable folding conformations of isogenic p
Publikováno v:
Evolution; international journal of organic evolutionLITERATURE CITED. 74(4)
An important driver of evolution in viruses is natural selection to optimize the use of their hosts' genetic network. To learn how viruses respond to this pressure, we disrupted the genetic network of Escherichia coli to inhibit replication of its vi
Autor:
Stephanie J. Spielman, Daniel T Johnson, Meyer, Katherine L. Petrie, Rohan Maddamsetti, Debbie Marks
Viral gain-of-function mutations are commonly observed in the laboratory; however, it is unknown whether those mutations also evolve in nature. We identify two key residues in the host recognition protein of bacteriophage λ that are necessary to exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af093105a3405340eacaaa3a2092acd1
https://doi.org/10.1101/242495
https://doi.org/10.1101/242495
Autor:
Katherine L. Petrie, Gerald F. Joyce
Publikováno v:
Nucleic Acids Research
Next-generation DNA sequencing technology was used to score >100 000 mutations resulting from exposure of a nucleic acid template to a mutagenic dNTP analog during a single pass of a DNA polymerase. An RNA template of known secondary structure was re
Autor:
Katherine L. Petrie, Gerald F. Joyce
The relative contributions of adaptive selection and neutral drift to observed genetic change are unknown, but likely depend on the inherent abundance of functional genotypes in sequence space and how accessible those genotypes are to one another. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7681d196b0fb741c6a1b722b79f04074
https://europepmc.org/articles/PMC4185262/
https://europepmc.org/articles/PMC4185262/