GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL).

Autor: Morten F Gjerstorff, Heike I Rösner, Christina B Pedersen, Katrine B V Greve, Steffen Schmidt, Katherine L Wilson, Jan Mollenhauer, Hüseyin Besir, Flemming M Poulsen, Niels Erik Møllegaard, Henrik J Ditzel

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45819 (2012)

GAGE proteins are highly similar, primate-specific molecules with unique primary structure and undefined cellular roles. They are restricted to cells of the germ line in adult healthy individuals, but are broadly expressed in a wide range of cancers.

Externí odkaz: https://doaj.org/article/caa21b9d79494282bf95567b6de2f1c9

Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane.

Autor: James M Holaska, Amy K Kowalski, Katherine L Wilson

Publikováno v: PLoS Biology, Vol 2, Iss 9, p E231 (2004)

X-linked Emery-Dreifuss muscular dystrophy is caused by loss of emerin, a LEM-domain protein of the nuclear inner membrane. To better understand emerin function, we used affinity chromatography to purify emerin-binding proteins from nuclear extracts

Externí odkaz: https://doaj.org/article/f3d37424c6eb493ab31991629bc0f791

Acute downregulation of emerin alters actomyosin cytoskeleton connectivity and function

Autor: Qianru Jin, Deepesh Pandey, Carol B. Thompson, Shawna Lewis, Hyun Woo Sung, Thao D. Nguyen, Scot Kuo, Katherine L. Wilson, David H. Gracias, Lewis H. Romer

Publikováno v: Biophysical Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf4296bea8e8a01ae157e4ee5eb6460e
https://doi.org/10.1016/j.bpj.2023.05.027

Helping Scholars Overcome Socioeconomic Barriers to Medical and Biomedical Careers: Creating a Pipeline Initiative

Autor: Cathryn Kabacoff, Deidra C. Crews, Chiquita A. Collins, Katherine L. Wilson, Catherine Will, Sarah L. Poynton, Jessica Bolz, Laura R. Murphy, Estelle B. Gauda, Paul T. White, Jungsan Sohn, Andrew Wolfe, Douglas N. Robinson

Publikováno v: Teaching and Learning in Medicine. 32:422-433

Problem: To achieve their potential in medical and biomedical careers, students (scholars) from under-resourced backgrounds must build sophisticated skills and develop confidence and professionalism. To flourish in an advanced educational system that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f863068447ef24a547d4bf0843c907a
https://doi.org/10.1080/10401334.2020.1729161

Rare BANF1 Alleles and Relatively Frequent EMD Alleles Including 'Healthy Lipid' Emerin p.D149H in the ExAC Cohort

Autor: Katherine L. Wilson, Julie Liu, Catherine Badens, Youchen Guan, Bénédicte Gaborit, Tejas Dharmaraj

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Frontiers media, 2019, 7, ⟨10.3389/fcell.2019.00048⟩
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2019, 7, ⟨10.3389/fcell.2019.00048⟩
Frontiers in Cell and Developmental Biology, 2019, 7, ⟨10.3389/fcell.2019.00048⟩
Frontiers in Cell and Developmental Biology (7), . (2019)
Frontiers in Cell and Developmental Biology, Vol 7 (2019)

International audience; Emerin (EMD) and barrier to autointegration factor 1 (BANF1) each bind A-type lamins (LMNA) as fundamental components of nuclear lamina structure. Mutations in LMNA, EMD and BANF1 are genetically linked to many tissue-specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5ae50368e55e9645cc79801e925f3d
https://hal-amu.archives-ouvertes.fr/hal-02461456