Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Katherine L Tuggle"'
1
Akademický článek
Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat.
Autor: Michael S Stalvey, Viktoria Havasi, Katherine L Tuggle, Dezhi Wang, Susan Birket, Steve M Rowe, Eric J Sorscher
Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0188497 (2017)
Reduced growth and osteopenia are common in individuals with cystic fibrosis (CF). Additionally, improved weight and height are associated with better lung function and overall health in the disease. Mechanisms for this reduction in growth are not un
Externí odkaz: https://doaj.org/article/cfa00dd154ca48499e2e5f75af837c60
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2
Akademický článek
Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats.
Autor: Katherine L Tuggle, Susan E Birket, Xiaoxia Cui, Jeong Hong, Joe Warren, Lara Reid, Andre Chambers, Diana Ji, Kevin Gamber, Kengyeh K Chu, Guillermo Tearney, Li Ping Tang, James A Fortenberry, Ming Du, Joan M Cadillac, David M Bedwell, Steven M Rowe, Eric J Sorscher, Michelle V Fanucchi
Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91253 (2014)
Animal models for cystic fibrosis (CF) have contributed significantly to our understanding of disease pathogenesis. Here we describe development and characterization of the first cystic fibrosis rat, in which the cystic fibrosis transmembrane conduct
Externí odkaz: https://doaj.org/article/cda01f9339b140bb92a4e09c988812c8
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4
Development of an airway mucus defect in the cystic fibrosis rat
Autor: Guillermo J. Tearney, Susan E. Birket, Steven M. Rowe, Kengyeh K. Chu, Michelle V. Fanucchi, Katherine L. Tuggle, Joy M. Davis, Courtney M. Fernandez, Eric J. Sorscher, Ashley M Oden
Publikováno v: JCI Insight. 3
The mechanisms underlying the development and natural progression of the airway mucus defect in cystic fibrosis (CF) remain largely unclear. New animal models of CF, coupled with imaging using micro-optical coherence tomography, can lead to insights
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b483014765956ac789064ad8382c8a4
https://doi.org/10.1172/jci.insight.97199
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6
Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat
Autor: Katherine L. Tuggle, Michael S. Stalvey, Viktória Havasi, Susan E. Birket, Eric J. Sorscher, S M. Rowe, Dezhi Wang
Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0188497 (2017)
PLoS ONE
Background Reduced growth and osteopenia are common in individuals with cystic fibrosis (CF). Additionally, improved weight and height are associated with better lung function and overall health in the disease. Mechanisms for this reduction in growth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9cde4d2a16fc6b680fba79c51ceb27
http://europepmc.org/articles/PMC5708703?pdf=render
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7
Considerations for the Conduct of Clinical Trials with Antiinflammatory Agents in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report
Autor: Theodore J, Torphy, Janet, Allen, André M, Cantin, Michael W, Konstan, Frank J, Accurso, Elizabeth, Joseloff, Felix A, Ratjen, James F, Chmiel, Katherine L, Tuggle
Publikováno v: Annals of the American Thoracic Society. 12(9)
Inflammation leads to lung destruction and loss of pulmonary function in patients with cystic fibrosis (CF). Drugs that modulate the cystic fibrosis transmembrane conductance regulator (CFTR) have recently been approved. Although the impact of CFTR m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cece52a1a0bcee9b855dbfd200d63363
https://pubmed.ncbi.nlm.nih.gov/26146892
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8
Age-Specific Difference in Pulmonary Cellular Injury and Mitochondrial Damage
Autor: Michelle V. Fanucchi, Katherine L. Tuggle
Publikováno v: Mitochondrial Function in Lung Health and Disease ISBN: 9781493908288
The impact of lung-targeted toxicants on the respiratory system of developing and aging animals is not well defined, let alone the role that mitochondria may play in the cascade of factors involved in cellular injury. Environmentally induced pulmonar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3966c19848390d609d1e8def74c9a43
https://doi.org/10.1007/978-1-4939-0829-5_9
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9
Site-specific dynamics of CD11b+ and CD103+ dendritic cell accumulations following ozone exposure
Autor: Michelle V. Fanucchi, Katherine L. Tuggle, Jeffrey D. Brand, Lisa M. Schwiebert, Edward M. Postlethwait, Carol A. Ballinger
Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 303(12)
Pulmonary dendritic cells (DCs) are among the first responders to inhaled environmental stimuli such as ozone (O3), which has been shown to activate these cells. O3 reacts with epithelial lining fluid (ELF) components in an anatomically site-specific
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac17b0fc59bace9f274afbf2fa53dc
https://pubmed.ncbi.nlm.nih.gov/23087018
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