Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Katherine L Suchland"'
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35373 (2012)
Regulation of chloride gradients is a major mechanism by which excitability is regulated in neurons. Disruption of these gradients is implicated in various diseases, including cystic fibrosis, neuropathic pain and epilepsy. Relatively few studies hav
Externí odkaz:
https://doaj.org/article/bb656aae16924878922bf5f633ee2895
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb18195e276f9afcbc2db753e0e7888f
https://doi.org/10.1096/fasebj.2020.34.s1.03720
https://doi.org/10.1096/fasebj.2020.34.s1.03720
Publikováno v:
The Journal of Physiology. 593:217-230
Key points Electrical stimulation of the rostral ventromedial medulla (RVM) facilitates pain behaviours in neonates but inhibits these behaviours in adults. The cellular mechanisms underlying these changes in RVM modulation of pain behaviours are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfaa58b43a191facae57912c547530ce
https://doi.org/10.1113/jphysiol.2014.275701
https://doi.org/10.1113/jphysiol.2014.275701
Publikováno v:
British Journal of Pharmacology. 172:549-561
Background and Purpose Opioids, such as morphine, are the most effective treatment for pain but their efficacy is diminished with the development of tolerance following repeated administration. Recently, we found that morphine activated ERK in opioid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d6ff84a9a13c63ca8a776de91115a0
https://doi.org/10.1111/bph.12703
https://doi.org/10.1111/bph.12703
Autor:
Madeline Grandy, Edmund A. Reese, Yohei Norimatsu, David K. Grandy, Katherine L. Suchland, James R. Bunzow
Publikováno v:
Journal of Medicinal Chemistry. 57:378-390
Amphetamines are widely abused drugs that interfere with dopamine transport and storage. Recently, however, another mechanism of action was identified: stereoselective activation of the GαS protein-coupled trace amine-associated receptor 1 (TAAR1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4c72343119aaf4b3028c509a980ee1
https://doi.org/10.1021/jm401316v
https://doi.org/10.1021/jm401316v
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(3)
The rostral ventromedial medulla (RVM) is a relay in the descending pain modulatory system and an important site of endocannabinoid modulation of pain. Endocannabinoids inhibit GABA release in the RVM, but it is not known whether this effect persists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca40d5b170ec2ab11e291e0643ba3cb
https://pubmed.ncbi.nlm.nih.gov/28100744
https://pubmed.ncbi.nlm.nih.gov/28100744
Autor:
Kathleen A. Beeson, Janet D. Lowe, Karen J. Tonsfeldt, Katherine L. Suchland, Minghua Li, Susan L. Ingram
The ventrolateral periaqueductal gray (vlPAG) is a key structure in the descending pain modulatory circuit. Activation of the circuit occurs via disinhibition of GABAergic inputs onto vlPAG output neurons. In these studies, we tested the hypothesis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0446a2fac59be2e41a2f51fc8126593
https://europepmc.org/articles/PMC4737776/
https://europepmc.org/articles/PMC4737776/
Autor:
Nora D. Volkow, Gene-Jack Wang, Ujval B. Patel, David K. Grandy, Brenda J. Anderson, John K. Robinson, Michael Michaelides, Panayotis K. Thanos, Katherine L. Suchland, Rahila Habibi
Publikováno v:
Behavioural Brain Research. 207:508-511
In this study we examined the genetic contribution of the D4R in food and cocaine self-administration using D4R mice. Mice were examined for operant responding to food pellets or intravenous cocaine. Compared to wild-type mice (D4R+/+), both heterozy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac53d22c2f6dafab9fdffdfd44ac8a23
https://doi.org/10.1016/j.bbr.2009.10.020
https://doi.org/10.1016/j.bbr.2009.10.020
Autor:
Paul J. Kruzich, David K. Grandy, B. Matthew Joyce, Clelland R. Gash, Erin C. Rutherford, Greg A. Gerhardt, Paul E.A. Glaser, Stewart P. Surgener, Katherine L. Suchland, Theresa Currier Thomas
Publikováno v:
Journal of Neuroscience Methods. 166:306-314
Dopamine D4 receptor (D4R) knockout mice (D4R-/-) provided for unique neurochemical studies designed to understand D4R contributions to dopamine (DA) regulation. In this study, post-mortem brain tissue content of DA did not differ between D4R+/+ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0bbe88a65931542dd33f06bf6c99a
https://doi.org/10.1016/j.jneumeth.2007.03.009
https://doi.org/10.1016/j.jneumeth.2007.03.009
Autor:
Thomas M.P. Ciesielski, Katherine L. Suchland, Mary P. Stenzel-Poore, Nikola S. Lessov, Thomas S. Scanlan, David K. Grandy, Kristian P. Doyle
Publikováno v:
Stroke. 38:2569-2576
Background and Purpose— Mild hypothermia confers profound neuroprotection in ischemia. We recently discovered 2 natural derivatives of thyroxine, 3-iodothyronamine (T 1 AM) and thyronamine (T 0 AM), that when administered to rodents lower body temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31609123a89a66289c703c9d03f91685
https://doi.org/10.1161/strokeaha.106.480277
https://doi.org/10.1161/strokeaha.106.480277