Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katherine L Farley"'
Autor:
Wenjun Ni, Jia Ji, Zunyan Dai, Audrey Papp, Amy J Johnson, Sunjoo Ahn, Katherine L Farley, Thomas S Lin, James T Dalton, Xiaobai Li, David Jarjoura, John C Byrd, Wolfgang Sadee, Michael R Grever, Mitch A Phelps
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13792 (2010)
Flavopiridol is a cyclin-dependent kinase inhibitor in phase II clinical development for treatment of various forms of cancer. When administered with a pharmacokinetically (PK)-directed dosing schedule, flavopiridol exhibited striking activity in pat
Externí odkaz:
https://doaj.org/article/d855ac1e3ffb492e8c542945d869e74a
Autor:
John C. Byrd, Amy J. Johnson, Michael R. Grever, Natarajan Muthusamy, Larry J. Schaaf, Kristie A. Blum, Katherine L. Farley, James T. Dalton, Craig C. Hofmeister, Qing Liu, Mitch A. Phelps
Publikováno v:
Therapeutic Drug Monitoring. 30:620-627
Lenalidomide, an immunomodulatory agent, and flavopiridol, a broad cyclin-dependent kinase inhibitor, are active therapies for clinical use in genomic high-risk chronic lymphocytic leukemia. A high-performance liquid chromatographic assay with tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9528a22b388889b263fa3f93f7e9b17d
https://doi.org/10.1097/ftd.0b013e318185813d
https://doi.org/10.1097/ftd.0b013e318185813d
Autor:
William Blum, Michael R. Grever, Jeffrey S. Johnston, Katherine L. Farley, James T. Dalton, Mitch A. Phelps, Kristie A. Blum
Publikováno v:
Journal of Chromatography B. 871:15-21
A sensitive method was developed and validated for the measurement of 17-(allylamino)-17-demethoxygeldanamycin (17AAG) and its active metabolite 17-amino-17-demethoxygeldanamycin (17AG) in human plasma using 17-(dimethylaminoethylamino)-17-demethoxyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee751a3d68ce0d9b06354dca9155dcf
https://doi.org/10.1016/j.jchromb.2008.06.029
https://doi.org/10.1016/j.jchromb.2008.06.029
Publikováno v:
The American journal of forensic medicine and pathology. 33(4)
It is essential that clinical physicians, medical personnel, medical examiners, and law enforcement agencies understand the types of injuries seen and demographics of children affected by intentional blunt force as this understanding can be crucial t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b46db6748f3c2d547b1dc0ad5eed26
https://pubmed.ncbi.nlm.nih.gov/21540721
https://pubmed.ncbi.nlm.nih.gov/21540721
Autor:
Katherine L. Farley, Larry J. Schaaf, Sarah M. Mitchell, Amy J. Johnson, Mitch A. Phelps, James T. Dalton, Eunju Hurh, David Jarjoura, Thomas S. Lin, Michael R. Grever, Beth Fischer, Nyla A. Heerema, Darlene M. Rozewski, Kristie A. Blum, Mollie E. Moran, Di Wu, Michelle Brooker-McEldowney, John C. Byrd
Publikováno v:
Blood. 113(12)
We previously reported interim results of a phase 1 trial in patients with chronic lymphocytic leukemia (CLL) whereby flavopiridol was administered intravenously as a 30-minute bolus followed by 4-hour infusion. We now report full pharmacokinetic (PK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39559a0a8db9cbebd503f3db2e8fb4da
https://pubmed.ncbi.nlm.nih.gov/18981292
https://pubmed.ncbi.nlm.nih.gov/18981292
Autor:
Darlene M. Rozewski, Thomas S. Lin, Jeffrey S. Johnston, Michael R. Grever, John C. Byrd, Mitch A. Phelps, Katie A. Albanese, Katherine L. Farley, James T. Dalton
A high-performance liquid chromatographic assay with tandem mass spectrometric detection was developed and validated for quantitation of the broad spectrum kinase inhibitor, flavopiridol, in human plasma. Sample preparation conditions included liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9432913a4ef0f895f4305dac0090d4a
https://europepmc.org/articles/PMC2504738/
https://europepmc.org/articles/PMC2504738/
