Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katherine L, Lucot"'
Autor:
Marc Y. Stevens, Haley C. Cropper, Katherine L. Lucot, Aisling M. Chaney, Kendra J. Lechtenberg, Isaac M. Jackson, Marion S. Buckwalter, Michelle L. James
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background B cells play a central role in multiple sclerosis (MS) through production of injurious antibodies, secretion of pro-inflammatory cytokines, and antigen presentation. The therapeutic success of monoclonal antibodies (mAbs) targetin
Externí odkaz:
https://doaj.org/article/ad016d6b312c48d6b055371bec97535a
Autor:
Samantha G. Scharenberg, Edina Poletto, Katherine L. Lucot, Pasqualina Colella, Adam Sheikali, Thomas J. Montine, Matthew H. Porteus, Natalia Gomez-Ospina
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Gaucher disease is a lysosomal storage disorder caused by insufficient glucocerebrosidase expression. Here, the authors describe a CRISPR/Cas9-based gene-editing approach to re-express this enzyme in human blood stem cells and show that they can engr
Externí odkaz:
https://doaj.org/article/224d60d712dd4dc594a6f383d84a1ecd
Autor:
Emily Z, Huie, Anthony, Escudero, Naomi, Saito, Danielle, Harvey, My-Le, Nguyen, Katherine L, Lucot, Jayne, LaGrande, Dan, Mungas, Charles, DeCarli, Melissa, Lamar, Julie A, Schneider, Alifiya, Kapasi, Robert A, Rissman, Andrew F, Teich, Brittany N, Dugger
Publikováno v:
Journal of Alzheimer's Disease. 91:1291-1301
Background: Transactive Response DNA Binding Protein 43 kDa (TDP-43) pathology is frequently found in cases with Alzheimer’s disease (AD). TDP-43 pathology is associated with hippocampal atrophy and greater AD severity denoted by cognition and clin
Semi-quantitative Assessment of Alzheimer's-like Pathology in Two Aged Polar Bears (Ursus maritimus)
Autor:
Katherine L Lucot, Syed A Bukhari, Ebony D Webber, T Adam Bonham, Corinna Darian-Smith, Thomas J Montine, Sherril L Green
Publikováno v:
Comparative Medicine. 72:267-272
Age-associated neurodegenerative changes, including amyloid β (Aβ) plaques, neurofibrillary tangles (NFTs), and amyloid angiopathy comparable to those seen in the brains of human patients with Alzheimer's disease (AD), have been reported in the bra
Autor:
Katherine L, Lucot, Syed A, Bukhari, Ebony D, Webber, T Adam, Bonham, Corinna, Darian-Smith, Thomas J, Montine, Sherril L, Green
Publikováno v:
Comp Med
Age-associated neurodegenerative changes, including amyloid β (Aβ) plaques, neurofibrillary tangles (NFTs), and amyloid angiopathy comparable to those seen in the brains of human patients with Alzheimer’s disease (AD), have been reported in the b
Autor:
Samantha G. Scharenberg, Edina Poletto, Katherine L. Lucot, Pasqualina Colella, Adam Sheikali, Thomas J. Montine, Matthew H. Porteus, Natalia Gomez-Ospina
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2e720a5bd5c646a59d52cf105a7df039
Autor:
Katherine L. Lucot, Welver Suarez, Kelsey Mifflin, Charles DeCarli, Jayne La Grande, Brittany N. Dugger
Publikováno v:
Biopreservation and Biobanking.
In 1984, the National Institute on Aging developed the Alzheimer's disease centers program. The main goal of these centers is to advance the understanding of Alzheimer's disease and related dementias (ADRD) through comprehensive patient evaluations a
Publikováno v:
Annu Rev Pathol
Alzheimer's disease (AD) is a pervasive, relentlessly progressive neurodegenerative disorder that includes both hereditary and sporadic forms linked by common underlying neuropathologic changes and neuropsychological manifestations. While a clinical
Autor:
Thomas J. Montine, Katherine L. Lucot, Adam Sheikali, Edina Poletto, Natalia Gomez-Ospina, Matthew H. Porteus, Samantha G. Scharenberg, Pasqualina Colella
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Gaucher disease is a lysosomal storage disorder caused by insufficient glucocerebroside activity. Its hallmark manifestations are attributed to infiltration and inflammation by macrophages. Current therapies for Gaucher disease include life−long in
Autor:
Marion S. Buckwalter, Michelle L. James, Isaac M. Jackson, Kendra J. Lechtenberg, Haley C. Cropper, Katherine L. Lucot, Aisling Chaney, Marc Y. Stevens
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background B cells play a central role in multiple sclerosis (MS) through production of injurious antibodies, secretion of pro-inflammatory cytokines, and antigen presentation. The therapeutic success of monoclonal antibodies (mAbs) targeting B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5c4e0228341946574d70239dca4508
https://doi.org/10.21203/rs.3.rs-19155/v1
https://doi.org/10.21203/rs.3.rs-19155/v1