Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katherine Kentistou"'
Human genetic studies have provided substantial insight into the biological mechanisms governing ovarian ageing, yet previous approaches have been largely restricted to assessing common genetic variation. Here we report analyses of rare (MAFZNF518A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98f96929291f6be3e00841901ac9b1ae
https://doi.org/10.1101/2022.06.23.22276698
https://doi.org/10.1101/2022.06.23.22276698
Autor:
Rajkumar Dorajoo, Ozren Polasek, Stefania Bandinelli, Jette Bork-Jensen, Maria Knol, Claudia Langenberg, Stavroula Kanoni, Mika Kähönen, Bernhard Banas, Katherine Kentistou, Sailaja Vedantam, Gregory Marcus, Alicia Huerta-Chagoya, Yvonne Golightly, Deborah Malden, Claes Ohlsson, Loic Yengo, Petra Elders, Dharambir Sanghera, Masato Akiyama, Saori Sakaue, Eirini Marouli, Zi-Bing Jin, Maria Sabater Lleal
Common SNPs are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes. Here we show, using GWAS data from 5.4 million individuals of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a991d572e9e5cb1d4e5b075defda8f36
https://doi.org/10.1101/2022.01.07.475305
https://doi.org/10.1101/2022.01.07.475305
Autor:
Rajkumar Dorajoo, Jette Bork-Jensen, Blair Smith, Colin Palmer, Stavroula Kanoni, Bernhard Banas, Katherine Kentistou, Shweta Ramdas, Yuxuan Wang, Julia Ramírez, Ida Surakka, Jun Liu
Genetic variants within nearly 1,000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a201f585b8530696f867f1397f59700b
https://doi.org/10.1101/2021.12.15.21267852
https://doi.org/10.1101/2021.12.15.21267852
Autor:
Rajkumar Dorajoo, Ozren Polasek, Stefania Bandinelli, Joline Beulens, Jun Takayama, Jette Bork-Jensen, Blair Smith, Colin Palmer, Claudia Langenberg, Stavroula Kanoni, Mika Kähönen, Bernhard Banas, Katherine Kentistou, Alicia Huerta-Chagoya, Shweta Ramdas, Yvonne Golightly, Niek Verweij, Christian Fuchsberger, Claes Ohlsson, Petra Elders, Julia Ramírez, Masato Akiyama, Ida Surakka, Jun Liu, Zi-Bing Jin
A major challenge of genome-wide association studies (GWAS) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587487e5be509a32675fa1c64195a0d0
https://doi.org/10.1101/2021.12.07.470215
https://doi.org/10.1101/2021.12.07.470215