Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Katherine Kazakoff"'
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 21:59-67
The diabetic state that is seen at a high frequency in association with pancreatic cancer is characterized by elevated plasma levels of several islet hormones and by marked insulin resistance. Both the diabetic state and insulin sensitivity improve a
Publikováno v:
Cancer Letters. 117:155-160
The effect of a high-fat diet (HF) and streptozotocin (STZ) was investigated in the rapid cancer induction model developed in our laboratories. Syrian golden hamsters bearing homologous islets transplanted in their right submandibular gland (SMG) rec
Autor:
Shoji Nakamori, Lucio Gullo, Osamu Ishikawa, Silvia Franceschi, Hiroaki Ohigashi, J. Larsson, C Ferrara, L Brigato, Paola Fogar, Peter Boyle, Barbara D'Avanzo, Mario Plebani, Carlo La Vecchia, Daniela Basso, M.P. Panozzo, Masashito Mogaki, Joe Ariyama, Eva Negri, Åke Andrén-Sandberg, Katherine Kazakoff, Singi Imaoka, Tamara Meggiato, G. Del Favero, F. D’Angeli, Parviz M. Pour, Johan Permert, Jörgen Larsson, Raffaele Pezzilli, J. Permert, Thomas E. Adrian, Gunilla T. Westermark
Publikováno v:
International Journal of Pancreatology. 16:81-98
Autor:
Parviz M. Pour, Anton J. Bilchik, Margery K. Herrington, Thomas E. Adrian, Katherine Kazakoff, Johan Permert, Karl A. Zucker
Publikováno v:
Cancer Letters. 82:7-16
Raw soya diet in the hamster had short-term trophic effects on the pancreas, causing significant increases in pancreatic weight, DNA, RNA, and protein. These changes appear to be mediated by cholecystokinin (CCK) because the increases were blocked by
Publikováno v:
American Journal of Clinical Pathology. 100:223-230
Nine human exocrine pancreatic adenocarcinomas were examined by serial sectioning and double- and triple-labeled immunohistochemical techniques with antibodies against chromogranin A, insulin, islet amyloid polypeptide, glucagon, somatostatin, pancre
Autor:
Parviz M. Pour, Johan Permert, Margery K. Herrington, Anton J. Bilchik, Thomas E. Adrian, Karl A. Zuker, Katherine Kazakoff
Publikováno v:
Carcinogenesis. 14:1021-1026
The mechanism by which high-fat diet potentiates pancreatic cancer is not known, but trophic hormones may be involved. In preliminary growth studies, hamsters fed a high fat diet (17.5% lard, 17.5% corn oil) for 14 days showed a 16.3% increase (P < 0
Publikováno v:
Cancer Letters. 62:251-256
Cholecystokinin (CCK) inhibits pancreatic cancer but not hepatic tumor induction by N-nitrosobis (2-oxopropyl) amine (BOP) in hamsters when administered with or shortly before BOP. In this study, we evaluated the capability of sulfated CCK-8 to inhib
Publikováno v:
Pancreas. 17(4)
Diabetes associated with pancreatic cancer is characterized by profound peripheral insulin resistance. The intracellular mechanism of insulin resistance was investigated in skeletal muscles from N-nitrosobis(2-oxopropyl)amine (BOP)-treated hamsters.
Publikováno v:
International journal of pancreatology : official journal of the International Association of Pancreatology. 22(2)
Significant differences exist in the expression of transforming growth factor-alpha (TGF-alpha) in the submandibular glands (SMG) and the pancreas of different species and among cell components in the same species.Our previous studies have shown mark
Autor:
Thomas E. Adrian, Robert A. Cina, Katherine Kazakoff, Parviz M. Pour, Margery K. Herrington, T Gasslander, D M Fehsenfeld
Publikováno v:
Nutrition and cancer. 28(3)
The mechanism by which high-fat diets potentiate pancreatic cancer is not known, but pancreaticotrophic hormones such as cholecystokinin (CCK) may be involved. The effect of CCK receptor blockade on carcinogenesis during the entire promotion period w