Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Katherine Kalil"'
Autor:
Katherine Kalil, Sayantanee Biswas
Publikováno v:
The Journal of Neuroscience. 38:291-307
Proper organization and dynamics of the actin and microtubule (MT) cytoskeleton are essential for growth cone behaviors during axon growth and guidance. The MT-associated protein tau is known to mediate actin/MT interactions in cell-free systems but
Publikováno v:
Developmental Neurobiology
Wnt5a guides cortical axons in vivo by repulsion and in vitro evokes cortical axon outgrowth and repulsion by calcium signaling pathways. Here we examined the role of microtubule (MT) reorganization and dynamics in mediating effects of Wnt5a. Inhibit
Publikováno v:
Developmental Neurobiology
It has been shown in vivo that Wnt5a gradients surround the corpus callosum and guide callosal axons after the midline (postcrossing) by Wnt5a-induced repulsion via Ryk receptors. In dissociated cortical cultures we showed that Wnt5a simultaneously p
Autor:
Katherine Kalil, Fangjun Tang
Publikováno v:
The Journal of Neuroscience. 25:6702-6715
A single axon can innervate multiple targets by collateral branching. Axon branching is thus essential for establishing CNS connectivity. However, surprisingly little is known about the mechanisms by which branching is regulated. Axons often stop elo
Publikováno v:
The Journal of Neuroscience. 24:3002-3012
In many CNS pathways, target innervation occurs by axon branching rather than extension of the primary growth cone into targets. To investigate mechanisms of branch formation, we studied the effects of attractive and inhibitory guidance cues on corti
Publikováno v:
The Neuroscientist. 9:343-353
Growing axons are guided to appropriate targets by responses of their motile growth cones to environmental cues. Interstitial axon branching is also an important form of axon guidance in the mammalian CNS. Visualization of growing axons in cortical s
Autor:
Katherine Kalil, Erik W. Dent
The remarkable ability of a single axon to extend multiple branches and form terminal arbors enables vertebrate neurons to integrate information from divergent regions of the nervous system. Axons select appropriate pathways during development, but i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776bf6252ab6e4aed9e3b8d1e9664c61
https://europepmc.org/articles/PMC4063290/
https://europepmc.org/articles/PMC4063290/
Publikováno v:
Scopus-Elsevier
Interstitial branching is an important mechanism for target innervation in the developing CNS. A previous study of cortical neuronsin vitroshowed that the terminal growth cone pauses and enlarges in regions from which interstitial axon branches later
Publikováno v:
Journal of Neurobiology. 39:393-406
Corticospinal axon outgrowth in vivo and the ability to sprout or regenerate after injury decline with age. This developmental decline in growth potential has been correlated with an increase in inhibitory myelin-associated proteins in older spinal c
Publikováno v:
The Journal of Neuroscience. 18:7930-7940
Interstitial branches arise from the axon shaft, sometimes at great distances behind the primary growth cone. After a waiting period that can last for days after extension of the primary growth cone past the target, branches elongate toward their tar