Výsledky vyhledávání - "Katherine J. Wang"

Inhibition of Karyopherin beta 1 suppresses prostate cancer growth

Autor: Yuqi Guo, Katherine J. Wang, Jian Yang, Liang Luo, Catherine H. Chu, Ruohan Zhang, Yanli Zhang, Cuijie Lu, Sabrine I. Obbad, Yaoyu Wang, Wenbo Yan, Xin Li

Publikováno v: Oncogene

Prostate cancer (PCa) initiation and progression requires activation of numerous oncogenic signaling pathways. Nuclear-cytoplasmic transport of oncogenic factors is mediated by Karyopherin proteins during cell transformation. However, the role of nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ebdc35f597165c18307bf6b3046717
http://europepmc.org/articles/PMC6565446

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Sequence- and structure-based computational analyses of Gram-negative tripartite efflux pumps in the context of bacterial membranes

Autor: Timothy Travers, Katherine J. Wang, Sandrasegaram Gnanakaran, Cesar A. Lopez

Publikováno v: Research in Microbiology. 169:414-424

Gram-negative multidrug resistance currently presents a serious threat to public health with infections effectively rendered untreatable. Multiple molecular mechanisms exist that cause antibiotic resistance and in addition, the last three decades hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f718f80104051469e02ae48a8137a8e9
https://doi.org/10.1016/j.resmic.2018.01.002

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Mouse Model for Protein Tyrosine Phosphatase D (PTPRD) Associations with Restless Leg Syndrome or Willis-Ekbom Disease and Addiction: Reduced Expression Alters Locomotion, Sleep Behaviors and Cocaine-Conditioned Place Preference

Autor: Katherine J. Wang, G. Luke Hartstein, Yoichiro Iwakura, Donna Walther, George R. Uhl, Noriko Uetani, Bryson Lochte, Jana Drgonova, Juan C. Troncoso

Publikováno v: Molecular Medicine. 21:717-725

The receptor type protein tyrosine phosphatase D (PTPRD) gene encodes a cell adhesion molecule likely to influence development and connections of addiction-, locomotion- and sleep-related brain circuits in which it is expressed. The PTPRD gene harbor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67c1f07277226be6ca71114fab84fc3e
https://doi.org/10.2119/molmed.2015.00017

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Mouse Model for Protein Tyrosine Phosphatase D (

Autor: Jana, Drgonova, Donna, Walther, Katherine J, Wang, G Luke, Hartstein, Bryson, Lochte, Juan, Troncoso, Noriko, Uetani, Yoichiro, Iwakura, George R, Uhl

Publikováno v: Molecular medicine (Cambridge, Mass.). 21(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d34f35ebb1bba354f4cd6a92fcb880f5
https://pubmed.ncbi.nlm.nih.gov/26181631

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Mechanisms of Adipocytokine-Mediated Trastuzumab Resistance in HER2-Positive Breast Cancer Cell Lines

Autor: Jayashree P. Joshi, Rita Nahta, Samantha E. Griner, Katherine J. Wang

Publikováno v: Current pharmacogenomics and personalized medicine. 11(1)

Acquired resistance to trastuzumab is a clinical problem in the treatment of HER2-over-expressing metastatic breast cancer. Importantly, an earlier report suggested that high body mass index was associated with reduced overall survival and reduced ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631daa97b25a85aee0c8db738e251029
https://pubmed.ncbi.nlm.nih.gov/24179558

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