Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Katherine J. D. A. Excoffon"'
Autor:
Poornima Kotha Lakshmi Narayan, James M. Readler, Mahmoud S. Alghamri, Trisha L. Brockman, Ran Yan, Priyanka Sharma, Vladislav Snitsarev, Katherine J. D. A. Excoffon, Abimbola O. Kolawole
Publikováno v:
Pathogens, Vol 11, Iss 2, p 173 (2022)
The coxsackievirus and adenovirus receptor (CAR) is an essential cellular protein that is involved in cell adhesion, cell signaling, and viral infection. The 8-exon encoded isoform (CAREx8) resides at the apical surface of polarized epithelia, where
Externí odkaz:
https://doaj.org/article/39c86d8393f14fdc8aa9f59971d4a1e5
Autor:
James M. Readler, Meghan R. Burke, Priyanka Sharma, Katherine J. D. A. Excoffon, Abimbola O. Kolawole
Publikováno v:
Viruses, Vol 14, Iss 1, p 13 (2021)
Human adenoviruses (HAdV) cause a variety of infections in human hosts, from self-limited upper respiratory tract infections in otherwise healthy people to fulminant pneumonia and death in immunocompromised patients. Many HAdV enter polarized epithel
Externí odkaz:
https://doaj.org/article/98b75f19b4644b61b48bd741251a8693
Publikováno v:
Biology of the Cell. 114:185-198
MAGI-1 is a critical cellular scaffolding protein with over 110 different cellular and microbial protein interactors. Since the discovery of MAGI-1 in 1997, MAGI-1 has been implicated in diverse cellular functions such as polarity, cell-cell communic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73359442e36053197ab0d378f465a723
https://doi.org/10.1111/boc.202200014
https://doi.org/10.1111/boc.202200014
Autor:
Katherine J. D. A. Excoffon
Publikováno v:
FEBS Letters. 594:1828-1837
The coxsackievirus and adenovirus receptor (CAR) is an essential multifunctional cellular protein that is only beginning to be understood. CAR serves as a receptor for many adenoviruses, human group B coxsackieviruses, swine vesicular disease virus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9892b050ca22b3bd79cbb87a1fe745
https://doi.org/10.1002/1873-3468.13794
https://doi.org/10.1002/1873-3468.13794
Autor:
Poornima L N Kotha, Priyanka Sharma, Abimbola O Kolawole, Ran Yan, Mahmoud S Alghamri, Trisha L Brockman, Julian Gomez-Cambronero, Katherine J D A Excoffon
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004696 (2015)
Prevention of viral-induced respiratory disease begins with an understanding of the factors that increase or decrease susceptibility to viral infection. The primary receptor for most adenoviruses is the coxsackievirus and adenovirus receptor (CAR), a
Externí odkaz:
https://doaj.org/article/275f285828614c40bffe7475725a9901
Publikováno v:
Virology
The Coxsackievirus and adenovirus receptor (CAR) is both a viral receptor and cell adhesion protein. CAR has two transmembrane isoforms that localize distinctly in polarized epithelial cells. Whereas the seven exon-encoded isoform (CAR(Ex7)) exhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c0870d9825e6ed1320a677b4ca8da3
https://doi.org/10.1016/j.virol.2019.07.018
https://doi.org/10.1016/j.virol.2019.07.018
Autor:
S. Dean Rider, Katherine J. D. A. Excoffon, Mahmoud S. Alghamri, Timothy L. Williamson, Abimbola O. Kolawole, Heather A. Hostetler, Priyanka Sharma, James M. Readler, Ran Yan, David R. Cool
Publikováno v:
J Virol
Adenoviruses (AdVs) are etiological agents of gastrointestinal, heart, eye, and respiratory tract infections that can be lethal for immunosuppressed people. Many AdVs use the coxsackievirus and adenovirus receptor (CAR) as a primary receptor. The CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25b7dca6f06801f2d406a04604ba1eb
https://pubmed.ncbi.nlm.nih.gov/33762416
https://pubmed.ncbi.nlm.nih.gov/33762416
Publikováno v:
MethodsX
MethodsX, Vol 7, Iss, Pp 101149-(2020)
MethodsX, Vol 7, Iss, Pp 101149-(2020)
CRISPR-Cas9 gene editing has made it possible to specifically edit genes in a myriad of target cells. Here, a method for isoform-specific editing and clonal selection in Madin-Darby canine kidney (MDCK) epithelial cells is described in detail. This a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e7f1582ac5e1b2a68dc56236a44a41
http://europepmc.org/articles/PMC7718483
http://europepmc.org/articles/PMC7718483
Autor:
Priyanka Sharma, Abimbola O Kolawole, Susan B Core, Adriana E Kajon, Katherine J D A Excoffon
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49930 (2012)
Although significant epidemiological evidence indicates that cigarette smoke exposure increases the incidence and severity of viral infection, the molecular mechanisms behind the increased susceptibility of the respiratory tract to viral pathogens ar
Externí odkaz:
https://doaj.org/article/acb555c647bc441187b0034a2846e1b3
Autor:
Katherine J D A Excoffon, Nicholas D Gansemer, Matthew E Mobily, Philip H Karp, Kalpaj R Parekh, Joseph Zabner
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9909 (2010)
Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells. However, CAR is a cell adhesion molecule localized on the basolateral membrane of polarized
Externí odkaz:
https://doaj.org/article/9e7f9695193f4750bc029b97ca4bffa7