Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Katherine J O'Malley"'
Autor:
Douglas S Reed, Anita K McElroy, Dominique J Barbeau, Cynthia M McMillen, Natasha L Tilston-Lunel, Shamkumar Nambulli, Emily Cottle, Theron C Gilliland, Hasala Rannulu, Jeneveve Lundy, Emily L Olsen, Katherine J O'Malley, Mengying Xia, Amy L Hartman, Thomas C Luke, Kristi Egland, Christoph Bausch, Hua Wu, Eddie J Sullivan, William B Klimstra, W Paul Duprex
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0290909 (2024)
Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An initial concern was the potential for vaccine- or antibody-dependent enhancement (ADE) of disease as had been reported with other coronaviruses. To evaluate this
Externí odkaz:
https://doaj.org/article/e111baf91dfb4fc09c7205841d90cc09
Autor:
Henry Ma, Joseph R Albe, Theron Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Noah Salama, Katherine J O'Malley, Ivona Pandrea, Tobias Teichert, Stacey Barrick, William B Klimstra, Amy L Hartman, Douglas S Reed
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1009946 (2022)
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pa
Externí odkaz:
https://doaj.org/article/a9ae6f80485742ccbbc0ae30019f063d
Autor:
Joseph R Albe, Henry Ma, Theron H Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Katherine J O'Malley, Noah Salama, Aaron W Walters, Ivona Pandrea, Tobias Teichert, William B Klimstra, Douglas S Reed, Amy L Hartman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009308 (2021)
Aerosol exposure to eastern equine encephalitis virus (EEEV) can trigger a lethal viral encephalitis in cynomolgus macaques which resembles severe human disease. Biomarkers indicative of central nervous system (CNS) infection by the virus and lethal
Externí odkaz:
https://doaj.org/article/148107b18d2d4b4295040268973f0ef0
Autor:
Amy L Hartman, Sham Nambulli, Cynthia M McMillen, Alexander G White, Natasha Louise Tilston-Lunel, Joseph R Albe, Emily Cottle, Matthew D Dunn, L James Frye, Theron H Gilliland, Emily L Olsen, Katherine J O'Malley, Madeline M Schwarz, Jaime A Tomko, Reagan C Walker, Mengying Xia, Matthew S Hartman, Edwin Klein, Charles A Scanga, JoAnne L Flynn, William B Klimstra, Anita K McElroy, Douglas S Reed, W Paul Duprex
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008903 (2020)
Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (A
Externí odkaz:
https://doaj.org/article/9af9b959abac4308b999b6e2d34961ea
Autor:
Henry Ma, Jeneveve D Lundy, Emily L Cottle, Katherine J O'Malley, Anita M Trichel, William B Klimstra, Amy L Hartman, Douglas S Reed, Tobias Teichert
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0232381 (2020)
Alphaviruses such as Venezuelan equine encephalitis virus (VEEV) and Eastern equine encephalitis virus (EEEV) are arboviruses that can cause severe zoonotic disease in humans. Both VEEV and EEEV are highly infectious when aerosolized and can be used
Externí odkaz:
https://doaj.org/article/b5ecf1b03da445c3a3f1211a99c6fa94
Autor:
Katherine J O'Malley, Jennifer D Bowling, Elizabeth Stinson, Kelly S Cole, Barbara J Mann, Prachi Namjoshi, Karsten R O Hazlett, Eileen M Barry, Douglas S Reed
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205928 (2018)
Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of attempts to develop a vaccine for Ft, few candidates have advanced beyo
Externí odkaz:
https://doaj.org/article/2fd974cb829c404a8034e7d2e715d828
Autor:
Laura E Pascal, Junkui Ai, Khalid Z Masoodi, Yujuan Wang, Dan Wang, Kurtis Eisermann, Lora H Rigatti, Katherine J O'Malley, Hei M Ma, Xinhui Wang, Javid A Dar, Anil V Parwani, Brian W Simons, Michael M Ittman, Luyuan Li, Benjamin J Davies, Zhou Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79542 (2013)
ELL-associated factor 2 (EAF2) is an androgen-responsive tumor suppressor frequently deleted in advanced prostate cancer that functions as a transcription elongation factor of RNA Pol II through interaction with the ELL family proteins. EAF2 knockout
Externí odkaz:
https://doaj.org/article/2c2f1098dfe742f993dd09a4cac54f86
Autor:
Katherine J. O’Malley, Joseph R. Albe, Matthew D. Dunn, Emily L. Cottle, Cynthia M. McMillen, Ivona Pandrea, Henry Ma, Noah Salama, William B. Klimstra, Tobias Teichert, Stacey Barrick, Theron Gilliland, Jeneveve D. Lundy, Douglas S. Reed, Devin A. Boyles, Christina L. Gardner, Amy L. Hartman
Publikováno v:
PLoS pathogens. 18(6)
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pa
Autor:
Cynthia M. McMillen, Amy L. Hartman, Katherine J. O’Malley, Joseph R. Albe, Madeline M. Schwarz, Douglas S. Reed, Devin A. Boyles
Publikováno v:
The Journal of General Virology
The zoonotic emerging Rift Valley fever virus (RVFV) causes sporadic disease in livestock and humans throughout Africa and the Saudi Arabian peninsula. Infection of people with RVFV can occur through mosquito bite or mucosal exposure during butcherin
Autor:
JoAnne L. Flynn, Natasha L. Tilston-Lunel, Matthew S. Hartman, Matthew D. Dunn, Amy L. Hartman, Madeline M. Schwarz, Charles A. Scanga, Reagan C. Walker, Edwin Klein, Cynthia M. McMillen, Theron Gilliland, William B. Klimstra, Jaime A Tomko, Sham Nambulli, Mengying Xia, Douglas S. Reed, Emily L. Cottle, Emily L. Olsen, Katherine J. O’Malley, Anita K. McElroy, Joseph R. Albe, W. Paul Duprex, L. James Frye, Alexander G. White
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008903 (2020)
PLoS Pathogens
PLoS Pathogens
Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (A