Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Katherine J Motyl"'
Housing Temperature Influences Atypical Antipsychotic Drug‐Induced Bone Loss in Female C57BL/6J Mice
Publikováno v:
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
ABSTRACT Atypical antipsychotic (AA) drugs, such as risperidone, are associated with endocrine and metabolic side effects, including impaired bone mineral density (BMD) acquisition and increased fracture risk. We have previously shown that risperidon
Externí odkaz:
https://doaj.org/article/377baabe70224c96bc6ba75ffa29d884
Autor:
Adriana Lelis Carvalho, Annika Treyball, Daniel J Brooks, Samantha Costa, Ryan J Neilson, Michaela R Reagan, Mary L Bouxsein, Katherine J Motyl
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0231060 (2021)
Trpm8 (transient receptor potential cation channel, subfamily M, member 8) is expressed by sensory neurons and is involved in the detection of environmental cold temperatures. TRPM8 activity triggers an increase in uncoupling protein 1 (Ucp1)-depende
Externí odkaz:
https://doaj.org/article/953e1edcb71d47958ff718fb0188a599
Autor:
Christine W Lary, Alexandra C Hinton, Kathleen T Nevola, Theresa I Shireman, Katherine J Motyl, Karen L Houseknecht, F. Lee Lucas, Sarah Hallen, Andrew R Zullo, Sarah D Berry, Douglas P Kiel
Publikováno v:
JBMR Plus, Vol 4, Iss 9, Pp n/a-n/a (2020)
ABSTRACT Some, but not all, prior observational studies have shown that beta blocker (BB) use is associated with lower fracture risk and higher bone mineral density (BMD). Rodent studies show the mechanism to involve the reduction in the effects of b
Externí odkaz:
https://doaj.org/article/2b760bcb2b264e2d8201a6d5c32a44f0
Autor:
Audrie L. Langlais, Rebecca V. Mountain, Roni F. Kunst, Deborah Barlow, Karen L. Houseknecht, Katherine J. Motyl
Publikováno v:
Biochimie. Elsevier
Antipsychotic drugs are prescribed to a wide range of individuals to treat mental health conditions including schizophrenia. However, antipsychotic drugs cause bone loss and increase fracture risk. We previously found that the atypical antipsychotic
Autor:
Annika Treyball, Audrey C. Bergeron, Daniel J. Brooks, Audrie L. Langlais, Hina Hashmi, Kenichi Nagano, Deborah Barlow, Ryan J. Neilson, Tyler A. Roy, Kathleen T. Nevola, Karen L. Houseknecht, Roland Baron, Mary L. Bouxsein, Anyonya R. Guntur, Katherine J. Motyl
Publikováno v:
J Bone Miner Res
Although the non-selective β-blocker, propranolol, improves bone density with PTH treatment in mice, the mechanism of this effect is unclear. To address this, we used a combination of in vitro and in vivo approaches to address how propranolol influe
Autor:
Rebecca V. Mountain, Audrie L. Langlais, Dorothy Hu, Roland Baron, Christine W. Lary, Katherine J. Motyl
Publikováno v:
bioRxiv
Social isolation is a potent form of psychosocial stress and is a growing public health concern, particularly among older adults. Even prior to the onset of the COVID-19 pandemic, which has significantly increased the prevalence of isolation and lone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3150849cd1944ed705c7a61e581b84a
https://doi.org/10.1101/2023.01.27.525939
https://doi.org/10.1101/2023.01.27.525939
Autor:
Rebecca V. Mountain, Audrie L. Langlais, Dorothy Hu, Roland Baron, Christine W. Lary, Katherine J. Motyl
Publikováno v:
Bone. 172:116762
Autor:
Adriana Lelis Carvalho, Daniel J Brooks, Deborah Barlow, Audrie L Langlais, Breanna Morrill, Karen L Houseknecht, Mary L Bouxsein, Jane B Lian, Tamara King, Nicholas H Farina, Katherine J Motyl
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 37(11)
Opioid use is detrimental to bone health, causing both indirect and direct effects on bone turnover. Although the mechanisms of these effects are not entirely clear, recent studies have linked chronic opioid use to alterations in circulating miRNAs.
Housing Temperature Influences Atypical Antipsychotic Drug-Induced Bone Loss in Female C57BL/6J Mice
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
JBMR Plus, 5(10):e10541. Wiley-Blackwell Publishing Ltd
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
JBMR Plus, 5(10):e10541. Wiley-Blackwell Publishing Ltd
Atypical antipsychotic (AA) drugs, such as risperidone, are associated with endocrine and metabolic side effects, including impaired bone mineral density (BMD) acquisition and increased fracture risk. We have previously shown that risperidone causes
Autor:
Melissa M. Formosa, Douglas P. Kiel, Nicholas R Fuggle, Nathalie van der Velde, Archana Nagarajan, Katerina Trajanoska, Leo D. Westbury, Bruno H. Stricker, Kathleen T. Nevola, Cyrus Cooper, Fernando Rivadeneira, Alexandra Hinton, Katherine J. Motyl, Christine W. Lary, Angela Xuereb-Anastasi, Elaine M. Dennison
Publikováno v:
Journal of the Endocrine Society
Journal of the Endocrine Society, 5(8):bvab092. Endocrine Society
Journal of the Endocrine Society, 5(8):bvab092. Endocrine Society
CONTEXT: Recent studies have shown that β-blocker (BB) users have a decreased risk of fracture and higher bone mineral density (BMD) compared to nonusers, likely due to the suppression of adrenergic signaling in osteoblasts, leading to increased BMD