Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Katherine J Johnson"'
Autor:
Anna M. Jermakowicz, Alison M. Kurimchak, Katherine J. Johnson, Florence Bourgain-Guglielmetti, Simon Kaeppeli, Maurizio Affer, Hari Pradhyumnan, Robert K. Suter, Winston Walters, Maria Cepero, James S. Duncan, Nagi G. Ayad
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Bromodomain and extra-terminal domain (BET) proteins are therapeutic targets in several cancers including the most common malignant adult brain tumor glioblastoma (GBM). Multiple small molecule inhibitors of BET proteins have been utilized i
Externí odkaz:
https://doaj.org/article/4f50f991d1904053be9db08dafc453a4
Publikováno v:
Micromachines, Vol 15, Iss 8, p 1036 (2024)
Peripheral nerve modulation via electrical stimulation shows promise for treating several diseases, but current approaches lack selectivity, leading to side effects. Exploring selective neuromodulation with commercially available nerve cuffs is impra
Externí odkaz:
https://doaj.org/article/599f9043e9f04af88fcf4acfc0a8d394
Autor:
Basia Galinski, Marcus Luxemburg, Yosef Landesman, Bruce Pawel, Katherine J. Johnson, Stephen R. Master, Kevin W. Freeman, David M. Loeb, Jean M. Hébert, Daniel A. Weiser
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101114- (2021)
Across many cancer types in adults, upregulation of the nuclear-to-cytoplasmic transport protein Exportin-1 (XPO1) correlates with poor outcome and responsiveness to selinexor, an FDA-approved XPO1 inhibitor. Similar data are emerging in childhood ca
Externí odkaz:
https://doaj.org/article/df22e3a1000a4cbeba345adf608973b1
Autor:
Shuai Ye, Dinara Sharipova, Marya Kozinova, Lilli Klug, Jimson D’Souza, Martin G. Belinsky, Katherine J. Johnson, Margret B. Einarson, Karthik Devarajan, Yan Zhou, Samuel Litwin, Michael C. Heinrich, Ronald DeMatteo, Margaret von Mehren, James S. Duncan, Lori Rink
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Management of gastrointestinal stromal tumors (GISTs) has been revolutionized by the identification of activating mutations in KIT and PDGFRA and clinical application of RTK inhibitors in advanced disease. Stratification of GISTs into molecularly def
Externí odkaz:
https://doaj.org/article/bc77aa077101497c8a5b94060a37a94d
Publikováno v:
Earthquake Spectra. 38:2788-2812
Motivating property owners to mitigate seismic risks for existing buildings is a major challenge for many earthquake-prone regions. This article identifies primary factors that may affect the adoption of seismic retrofit by owners of commercial and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe3ddca057c51e863e942c96828d092
https://doi.org/10.1177/87552930221100844
https://doi.org/10.1177/87552930221100844
Autor:
Alison M. Kurimchak, Claude Shelton, Kelly E. Duncan, Katherine J. Johnson, Jennifer Brown, Shane O’Brien, Rashid Gabbasov, Lauren S. Fink, Yuesheng Li, Nicole Lounsbury, Magid Abou-Gharbia, Wayne E. Childers, Denise C. Connolly, Jonathan Chernoff, Jeffrey R. Peterson, James S. Duncan
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1273-1286 (2016)
Small-molecule BET bromodomain inhibitors (BETis) are actively being pursued in clinical trials for the treatment of a variety of cancers, but the mechanisms of resistance to BETis remain poorly understood. Using a mass spectrometry approach that glo
Externí odkaz:
https://doaj.org/article/e79692fa8e914be09f6af9dfa3135db9
Publikováno v:
Weather, Climate, and Society. 14:51-64
Climate adaptation is context specific, and inclusion of diverse forms of knowledge is crucial for developing resilient social–ecological systems. Emphasis on local inclusion is increasing, yet participatory approaches often fall short of facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0720d22305545543b24de20027dfa789
https://doi.org/10.1175/wcas-d-21-0047.1
https://doi.org/10.1175/wcas-d-21-0047.1
Publikováno v:
Journal of Earthquake Engineering. 26:6208-6235
This article reviews the current state of practice in seismic risk mitigation, focusing on policies in ten of the most earthquake-prone countries around the world. In particular, the review compare...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bdf4279f90255d782a7497eaa603d8d
https://doi.org/10.1080/13632469.2021.1911889
https://doi.org/10.1080/13632469.2021.1911889