Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katherine Hann"'
Autor:
Jean-Yves Douillard, Andrea Bezjak, Dongsheng Tu, Katherine Hann, Armando Santoro, Daniel Betticher, Luis Paz-Ares, Frances A. Shepherd, Christian Peschel, Maurizio Voi, Jeffrey S. Humphrey, Andrew Arnold, Jeffrey Crawford, Natasha B. Leighl, Lesley Seymour, Jacek Jassem, Susan M. Galbraith, Alain Depierre, Ulrich Gatzemeier
Publikováno v:
Journal of Clinical Oncology. 23:2831-2839
Purpose To determine whether BMS-275291, a broad-spectrum matrix metalloproteinase inhibitor (MMPI), added to systemic chemotherapy improved survival in advanced non–small-cell lung cancer (NSCLC). In early phase studies, BMS- 275291 was not associ
Autor:
Joshua A. Chu-Tan, Adrian V. Cioanca, Zhi-Ping Feng, Yvette Wooff, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Abstract Background MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with ar
Externí odkaz:
https://doaj.org/article/e8092aeac0204c3e936b785d776b9dc5
Publikováno v:
Genes, Vol 12, Iss 5, p 763 (2021)
Nucleoli form around actively transcribed ribosomal RNA (rRNA) genes (rDNA), and the morphology and location of nucleolus-associated genomic domains (NADs) are linked to the RNA Polymerase I (Pol I) transcription status. The number of rDNA repeats (a
Externí odkaz:
https://doaj.org/article/53153325278b49bc90c78b44d882e531
Autor:
Katherine Hann
Publikováno v:
South Asia Research. 5:59-72
Publikováno v:
Bio-Protocol, Vol 2, Iss 21 (2012)
p53, is known as the guardian of the genome and as such requires exquisite regulation not only of its abundance but also its activity. The abundance of p53 can be modulated at the level of transcription, translation, and also via its degradation.This
Externí odkaz:
https://doaj.org/article/020fbf8f9bfc47dba751e82e8e941345