Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Katherine G. Hamil"'
Autor:
Antoniel A. S. Gomes, Natália C. M. Santos, Leonardo R. Rosa, Rafael J. Borges, Marcos R. M. Fontes, Katherine G. Hamil, Michael G. O’Rand, Erick J. R. Silva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Novel male contraceptives will promote gender equality in sharing contraceptive responsibility. The sperm-associated protein epididymal protease inhibitor (EPPIN) is a promising target for non-hormonal male contraception. EPPIN interacts wit
Externí odkaz:
https://doaj.org/article/823afa632081474b9071c261e38fb539
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195953 (2018)
Men have two practical choices for contraception; the condom which has a high typical use failure rate or vasectomy. New male hormonal and non-hormonal contraceptives are under development that target either the production of sperm (spermatogenesis)
Externí odkaz:
https://doaj.org/article/31a98184d00f46589620b824060bea8a
Autor:
Nadia R Roan, Nathallie Sandi-Monroy, Nargis Kohgadai, Shariq M Usmani, Katherine G Hamil, Jason Neidleman, Mauricio Montano, Ludger Ständker, Annika Röcker, Marielle Cavrois, Jared Rosen, Kara Marson, James F Smith, Christopher D Pilcher, Friedrich Gagsteiger, Olena Sakk, Michael O’Rand, Polina V Lishko, Frank Kirchhoff, Jan Münch, Warner C Greene
Publikováno v:
eLife, Vol 6 (2017)
Unlike other human biological fluids, semen contains multiple types of amyloid fibrils in the absence of disease. These fibrils enhance HIV infection by promoting viral fusion to cellular targets, but their natural function remained unknown. The simi
Externí odkaz:
https://doaj.org/article/5f637bd10286422c90ea408f595c4cda
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82014 (2013)
Semenogelin I (SEMG1) is found in human semen coagulum and on the surface of spermatozoa bound to EPPIN. The physiological significance of the SEMG1/EPPIN interaction on the surface of spermatozoa is its capacity to modulate sperm progressive motilit
Externí odkaz:
https://doaj.org/article/375ddfd6a5db47568b1663c9aa9ee2d7
Autor:
Jan Münch, Marielle Cavrois, Kara Marson, Michael G. O'Rand, Nargis Kohgadai, Warner C. Greene, Olena Sakk, Annika Röcker, Christopher D. Pilcher, Shariq M. Usmani, Frank Kirchhoff, Nathallie Sandi-Monroy, Friedrich Gagsteiger, Ludger Ständker, Katherine G. Hamil, Polina V. Lishko, Mauricio Montano, Jared Rosen, Jason Neidleman, James F. Smith, Nadia R. Roan
Publikováno v:
eLife, Vol 6 (2017)
Roan, NR; Sandi-Monroy, N; Kohgadai, N; Usmani, SM; Hamil, KG; Neidleman, J; et al.(2017). Semen amyloids participate in spermatozoa selection and clearance. eLife, 6. doi: 10.7554/eLife.24888. UCSF: Retrieved from: http://www.escholarship.org/uc/item/09v2w1jh
eLife
Roan, NR; Sandi-Monroy, N; Kohgadai, N; Usmani, SM; Hamil, KG; Neidleman, J; et al.(2017). Semen amyloids participate in spermatozoa selection and clearance. eLife, 6. doi: 10.7554/eLife.24888. UCSF: Retrieved from: http://www.escholarship.org/uc/item/09v2w1jh
eLife
Unlike other human biological fluids, semen contains multiple types of amyloid fibrils in the absence of disease. These fibrils enhance HIV infection by promoting viral fusion to cellular targets, but their natural function remained unknown. The simi
Autor:
Polina V. Lishko, Jason Neidleman, James F. Smith, Michael G. O'Rand, Nadia R. Roan, Frank Kirchhoff, Mauricio Montano, Ludger Ständker, Nargis Kohgadai, Shariq M. Usmani, Christopher D. Pilcher, Friedrich Gagsteiger, Annika Röcker, Nathallie Sandi-Monroy, Olena Sakk, Jared Rosen, Jan Münch, Marielle Cavrois, Kara Marson, Katherine G. Hamil, Warner C. Greene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7402defcac8146ec4af643ffa8f97d19
https://doi.org/10.7554/elife.24888.029
https://doi.org/10.7554/elife.24888.029
Autor:
Michael G. O'Rand, Richard T. Richardson, Esther E. Widgren, Erick J. R. Silva, Katherine G. Hamil
Publikováno v:
Journal of Andrology. 32:698-704
The Laboratories for Reproductive Biology at the University of North Carolina at Chapel Hill began collaboration with Human Genome Sciences (Rockville, Maryland) to sequence a human epididymal library and identify epididymal-specific genes. Among the
Autor:
Gail Grossman, Susan H. Hall, Yashwanth Radhakrishnan, Katherine G. Hamil, Peter Petrusz, Luciana Honda, Frank S. French, Maria Christina W. Avellar, Suresh Yenugu
Publikováno v:
Biology of Reproduction. 76:1103-1116
Beta-defensins are small cationic peptides exhibiting broad spectrum antimicrobial properties. In humans, many beta-defensin genes are located within a cluster on chromosome 8p23. The sperm associated antigen 11 (SPAG11) gene is contained in this clu
Autor:
Frank S. French, Peter Petrusz, Gail Grossman, Susan H. Hall, Maria Christina W. Avellar, Katherine G. Hamil, Luciana Honda, Suresh Yenugu
Publikováno v:
Biology of Reproduction. 71:1453-1460
The epididymis protein 2 (EP2) gene, the fusion of two ancestral b-defensin genes, is highly expressed in the epididymis and subject to species-specific regulation at the levels of promoter selection, transcription, and mRNA splicing. EP2 mRNA expres
Publikováno v:
Endocrinology. 145:3165-3173
Spermatozoa bind a variety of proteins as they pass through the proximal regions of the epididymis, where they acquire forward motility and fertilizing ability. Recent evidence indicates that certain epididymis-specific secretory proteins that bind s