Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Katherine F Roby"'
Autor:
David Standing, Prasad Dandawate, Sumedha Gunewardena, Obdulia Covarrubias-Zambrano, Katherine F. Roby, Dineo Khabele, Andrea Jewell, Ossama Tawfik, Stefan H. Bossmann, Andrew K. Godwin, Scott J. Weir, Roy A. Jensen, Shrikant Anant
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-16 (2024)
Abstract Advanced epithelial ovarian cancer (EOC) survival rates are dishearteningly low, with ~25% surviving beyond 5 years. Evidence suggests that cancer stem cells contribute to acquired chemoresistance and tumor recurrence. Here, we show that IRA
Externí odkaz:
https://doaj.org/article/a34cd1f4ae354f69b2bfaed9395015fa
Autor:
Sheeja Rajasingh, Jayakumar Thangavel, Andras Czirok, Saheli Samanta, Katherine F Roby, Buddhadeb Dawn, Johnson Rajasingh
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134093 (2015)
Human induced pluripotent stem cells (iPSCs) derived cardiomyocytes (iCMCs) would provide an unlimited cell source for regenerative medicine and drug discoveries. The objective of our study is to generate functional cardiomyocytes from human iPSCs an
Externí odkaz:
https://doaj.org/article/ed77463c1658481b9cb2a92395473da6
Autor:
Shan Deng, Xiaojun Yang, Heini Lassus, Shun Liang, Sippy Kaur, Qunrui Ye, Chunsheng Li, Li-Ping Wang, Katherine F Roby, Sandra Orsulic, Denise C Connolly, Youcheng Zhang, Kathleen Montone, Ralf Bützow, George Coukos, Lin Zhang
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10277 (2010)
Aldehyde dehydrogenase isoform 1 (ALDH1) has been proved useful for the identification of cancer stem cells. However, our knowledge of the expression and activity of ALDH1 in common epithelial cancers and their corresponding normal tissues is still l
Externí odkaz:
https://doaj.org/article/ea58fb339551409982e852249ac192dc
Autor:
Shun Liang, Nuo Yang, Yue Pan, Shan Deng, Xiaojuan Lin, Xiaojun Yang, Dionyssios Katsaros, Katherine F Roby, Thomas C Hamilton, Denise C Connolly, George Coukos, Lin Zhang
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4295 (2009)
The Phosphatidylinositol 3'-kinase is a key regulator in various cancer-associated signal transduction pathways. Genetic alterations of its catalytic subunit alpha, PIK3CA, have been identified in ovarian cancer. Our in vivo data suggests that PIK3CA
Externí odkaz:
https://doaj.org/article/00c77ac734124550b63a784b55ad5563
Autor:
Andrew K. Godwin, Katherine F. Roby, Adam J. Krieg, Devin C. Koestler, Stefan Graw, Thuc Ly, Ziyan Y. Pessetto, Stephen Hyter, Harsh B. Pathak, Jeff Hirst
This document contains supplemental figures 1-17. Figure legends corresponding to each SF are on the subsequent page. Supplemental Figure 1. MCTS formation across a panel of ovarian cancer cell lines. Supplemental Figure 2. The number of proliferatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e28f2c34f81d6d63b85e2cbfd2672d8
https://doi.org/10.1158/0008-5472.22418459.v1
https://doi.org/10.1158/0008-5472.22418459.v1
Autor:
Andrew K. Godwin, Katherine F. Roby, Adam J. Krieg, Devin C. Koestler, Stefan Graw, Thuc Ly, Ziyan Y. Pessetto, Stephen Hyter, Harsh B. Pathak, Jeff Hirst
Expression of ABC transporter genes in 2D and in 3D cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8667a2f273c3e4457869dcfda92d8a2
https://doi.org/10.1158/0008-5472.22418456.v1
https://doi.org/10.1158/0008-5472.22418456.v1
Autor:
Andrew K. Godwin, Katherine F. Roby, Adam J. Krieg, Devin C. Koestler, Stefan Graw, Thuc Ly, Ziyan Y. Pessetto, Stephen Hyter, Harsh B. Pathak, Jeff Hirst
Drug development for first-line treatment of epithelial ovarian cancer (EOC) has been stagnant for almost three decades. Traditional cell culture methods for primary drug screening do not always accurately reflect clinical disease. To overcome this b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b728eef31988e02fb8656484d8b05a6
https://doi.org/10.1158/0008-5472.c.6510137.v1
https://doi.org/10.1158/0008-5472.c.6510137.v1
Autor:
Charles L. Sentman, Katherine F. Roby, Jose Conejo-Garcia, Leslie R. DeMars, Tong Zhang, Amorette Barber
Despite advancements in the treatment of ovarian cancer, this disease continues to be a leading cause of cancer death in women. Adoptive transfer of tumor-reactive T cells is a promising antitumor therapy for many cancers. We designed a chimeric rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e3b73378c8806c6c687f6f5ffc78d9
https://doi.org/10.1158/0008-5472.c.6495947.v1
https://doi.org/10.1158/0008-5472.c.6495947.v1
Autor:
Charles L. Sentman, Katherine F. Roby, Jose Conejo-Garcia, Leslie R. DeMars, Tong Zhang, Amorette Barber
Supplementary Figures 1-2 from Chimeric NKG2D Receptor–Bearing T Cells as Immunotherapy for Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd1ab93bea34a4fe5e34e0832196939
https://doi.org/10.1158/0008-5472.22368410
https://doi.org/10.1158/0008-5472.22368410
Autor:
Charles L. Sentman, Katherine F. Roby, Jose Conejo-Garcia, Leslie R. DeMars, Tong Zhang, Amorette Barber
Supplementary Tables 1-2 from Chimeric NKG2D Receptor–Bearing T Cells as Immunotherapy for Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef646a694ec736eb78441f4b25fb221
https://doi.org/10.1158/0008-5472.22368407
https://doi.org/10.1158/0008-5472.22368407