Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katherine Elisabeth Wiley"'
Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
Autor:
Katherine Elisabeth Wiley, David J. Nicholls, Fraser MacIntosh, Alasdair Gaw, Caroline Phillips, Carina Kärrman Mårdh, I.A. Dainty
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 353:340-350
In normal physiologic responses to injury and infection, inflammatory cells enter tissue and sites of inflammation through a chemotactic process regulated by several families of proteins, including inflammatory chemokines, a family of small inducible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2679a13b8fe51b994df69ec7e35f6f15
https://doi.org/10.1124/jpet.114.221358
https://doi.org/10.1124/jpet.114.221358
Autor:
Alasdair Gaw, Lorna Bowers, Tomkinson Nicholas, Katherine Elisabeth Wiley, Caroline Grahames, Philip Shelton, Tracey J. Wright, Anne Brammall, David J. Nicholls, Premji Meghani, Philip Mallinder
Publikováno v:
Molecular Pharmacology. 74:1193-1202
The chemokine receptors CXCR1 and CXCR2 are G-protein-coupled receptors (GPCRs) implicated in mediating cellular functions associated with the inflammatory response. Potent CXCR2 receptor antagonists have been discovered, some of which have recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bf6b4930b503d9d08551426de6f530
https://doi.org/10.1124/mol.107.044610
https://doi.org/10.1124/mol.107.044610
Autor:
Simon Young, Katherine Elisabeth Wiley, Kumar Changani, Tony Nials, Steve Jordan, Michael V. Haase, Richard G. Knowles, Simon P. Campbell, Kashmira Pindoria, Mike Pedrick, S J Bolton, Robert Shaw, Catherine Pereira
Publikováno v:
Clinical science (London, England : 1979). 125(12)
The present study investigated the role that imaging could have for assessing lung inflammation in a mouse model of HDM (house dust mite)-provoked allergic inflammation. Inflammation is usually assessed using terminal procedures such as BAL (bronchoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf17aaefd90a3ef8173635688c92ce48
https://pubmed.ncbi.nlm.nih.gov/23725401
https://pubmed.ncbi.nlm.nih.gov/23725401
Autor:
Richard G. Knowles, Simon Young, Kumar Changani, Katherine Elisabeth Wiley, Catherine Pereira, S J Bolton, Steve Jordan, Kashmira Pindoria, Tony Nials, Robert Shaw, Simon P. Campbell, Mike Pedrick, Michael V. Haase
Publikováno v:
Journal of Inflammation (London, England)
The present study investigated the role that imaging could have for assessing lung inflammation in a mouse model of a house dust mite (HDM) provoked allergic inflammation. Inflammation is usually assessed using terminal procedures such as bronchoalve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6086ecc9a2b8d7d9571e24a442b3779c
https://doi.org/10.1186/1476-9255-10-s1-p4
https://doi.org/10.1186/1476-9255-10-s1-p4