Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katherine E. Ryland"'
Autor:
Elizabeth R. Lawlor, Jeffrey R. Martens, Peter W. Laird, Scott C. Borinstein, Vasu Punj, Daniel J. Weisenberger, Allegra G. Hawkins, Katherine E. Ryland
KCNA5 promoter methylation in diverse cancer types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b4c74e25b254cb60c00b8134e55848
https://doi.org/10.1158/1541-7786.22511235.v1
https://doi.org/10.1158/1541-7786.22511235.v1
Autor:
Laurie K. Svoboda, Jeffrey R. Martens, Elizabeth R. Lawlor, Katherine E. Ryland, Eileen D. Vesely, Jeremy C. McIntyre, Lian Zhang
Publikováno v:
Oncogene
Relapse after clinical remission remains a leading cause of cancer-associated death. Although the mechanisms of tumor relapse are complex, the ability of cancer cells to survive physiological stress is a prerequisite for recurrence. Ewing sarcoma (ES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd52319e423ac90728cd74ab61a917bc
http://europepmc.org/articles/PMC4451446
http://europepmc.org/articles/PMC4451446
Autor:
Peter W. Laird, Vasu Punj, Daniel J. Weisenberger, Elizabeth R. Lawlor, Katherine E. Ryland, Scott C. Borinstein, Jeffrey R. Martens, Allegra G. Hawkins
Publikováno v:
Molecular cancer research : MCR. 14(1)
Polycomb proteins are essential regulators of gene expression in stem cells and development. They function to reversibly repress gene transcription via posttranslational modification of histones and chromatin compaction. In many human cancers, genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8545ff64c7537748b86ca8d643767c20
https://pubmed.ncbi.nlm.nih.gov/26573141
https://pubmed.ncbi.nlm.nih.gov/26573141
Autor:
Sarah M. Schumacher-Bass, Jeffrey R. Martens, Lian Zhang, Dyke P. McEwen, Robin M. Shaw, Jeremy C. McIntyre, Chad R. Frasier, Priscilla J. Chan, Eileen D. Vesely, Katherine E. Ryland
Publikováno v:
Circulation research. 114(6)
Rationale: Kv1.5 (KCNA5) mediates the ultra-rapid delayed rectifier current that controls atrial action potential duration. Given its atrial-specific expression and alterations in human atrial fibrillation, Kv1.5 has emerged as a promising target for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b655ddd09e927ec29e7572c33ba6ed
https://pubmed.ncbi.nlm.nih.gov/24508725
https://pubmed.ncbi.nlm.nih.gov/24508725
Autor:
Peter W. Laird, Scott C. Borinstein, Daniel J. Weisenberger, Elizabeth R. Lawlor, Katherine E. Ryland, Allegra G. Hawkins, Jeffrey R. Martens
Publikováno v:
Cancer Research. 75:3288-3288
Potassium channels regulate a variety of biological processes and dysfunction of these channels contributes to cancer initiation and progression. We recently showed that the KCNA5-encoded channel, Kv1.5, is a target of polycomb-group (PcG)-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de6ef5eb89a814126fd2fd413601a582
https://doi.org/10.1158/1538-7445.am2015-3288
https://doi.org/10.1158/1538-7445.am2015-3288
Publikováno v:
Cancer Research. 74:3968-3968
In Ewing sarcoma (ES) relapse is prevalent indicating that some cancer cells are resistant to treatment; however, the mechanism(s) governing treatment resistance and relapse are unknown. Voltage-gated potassium (Kv) channels play an essential role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b6ee365161f88f555415628257d7c4
https://doi.org/10.1158/1538-7445.am2014-3968
https://doi.org/10.1158/1538-7445.am2014-3968