Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Katherine E. Pendleton"'
Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Deregulation of tumor cell metabolism is widely recognized as a “hallmark of cancer.” Many of the selective pressures encountered by tumor cells, such as exposure to anticancer therapies, navigation of the metastatic cascade, and communication wi
Externí odkaz:
https://doaj.org/article/797819a65faf4f8f8c019ce148927a74
Autor:
Katherine E. Pendleton, Mokryun L. Baek, Junegoo Lee, Lin Tan, Hannah L. Johnson, Lacey E. Dobrolecki, James P. Barrish, Michael T. Lewis, Philip L. Lorenzi, Fabio Stossi, Gloria V. Echeverria
Publikováno v:
Cancer Research. 83:P6-11
Background: Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype for which limited targeted therapies are available. Therefore, conventional chemotherapy remains the backbone of standard neoadjuvant treatment (NACT) for TNBC pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f1fa69cc4206aa91aa6feea094f5ab
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-15
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-15
Autor:
Lily Baek, Junegoo Lee, Katherine E. Pendleton, Mariah J. Berner, Emily Goff, Lin Tan, Sara Martinez, Iqbal Mahmud, Argenis Arriojas, Alexander Zhurkevich, Tao Wang, Matthew Meyer, Bora Lim, James P. Barrish, Weston Porter, Kourosh Zarringhalam, Philip L. Lorenzi, Gloria V. Echeverria
Publikováno v:
Cancer Research. 83:P6-11
Background: Neoadjuvant chemotherapy (NACT) used for triple-negative breast cancer (TNBC) eradicates tumors in only 45% of patients. TNBC patients with substantial residual cancer burden have poor metastasis-free and overall survival rates. Our previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bfd14c1372d6b3a08806899d51735c9
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-14
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-14
Autor:
Madhav V. Dhodapkar, Kavita M. Dhodapkar, Sagar Lonial, Lawrence H. Boise, Stephen M. Ansell, Leonard T. Heffner, Jonathan L. Kaufman, Craig C. Hofmeister, Nisha S. Joseph, Vikas A. Gupta, Samuel S. McCachren, Julia Manalo, Benjamin G. Barwick, Katherine E. Pendleton, Allison R. Carr, Ajay K. Nooka, Akhilesh Kaushal
Waldenstrom macroglobulinemia (WM) and its precursor IgM gammopathy are distinct disorders characterized by clonal mature IgM-expressing B-cell outgrowth in the bone marrow. Here, we show by high-dimensional single-cell immunogenomic profiling of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93d618ae33aeb2a8f85aeaacba849c5
https://doi.org/10.1158/2643-3230.c.6550470.v1
https://doi.org/10.1158/2643-3230.c.6550470.v1
Autor:
Madhav V. Dhodapkar, Kavita M. Dhodapkar, Sagar Lonial, Lawrence H. Boise, Stephen M. Ansell, Leonard T. Heffner, Jonathan L. Kaufman, Craig C. Hofmeister, Nisha S. Joseph, Vikas A. Gupta, Samuel S. McCachren, Julia Manalo, Benjamin G. Barwick, Katherine E. Pendleton, Allison R. Carr, Ajay K. Nooka, Akhilesh Kaushal
supplementary figs 1-25 and supplementary tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061a62351cc1ed5248112cfa2facbf12
https://doi.org/10.1158/2643-3230.22543941
https://doi.org/10.1158/2643-3230.22543941
Autor:
Andrés Hernández-García, Katherine E Pendleton, Sangbae Kim, Yumei Li, Bum J Kim, Hitisha P Zaveri, Valerie K Jordan, Aliska M Berry, M Cecilia Ljungberg, Rui Chen, Rainer B Lanz, Daryl A Scott
Publikováno v:
Human Molecular Genetics.
SOX7 is a transcription factor-encoding gene located in a region on chromosome 8p23.1 that is recurrently deleted in individuals with ventricular septal defects (VSDs). We have previously shown that Sox7−/− embryos die of heart failure around E11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368181fa8752a662f186540cd0a9a609
https://doi.org/10.1093/hmg/ddad050
https://doi.org/10.1093/hmg/ddad050
Autor:
Katherine E. Pendleton, Andres Hernandez-Garcia, Jennifer M. Lyu, Ian M. Campbell, Chad A. Shaw, Julie Vogt, Frances A. High, Patricia K. Donahoe, Wendy K. Chung, Daryl A. Scott
Publikováno v:
Journal of Pediatric Genetics.
FOXP1 encodes a transcription factor involved in tissue regulation and cell-type-specific functions. Haploinsufficiency of FOXP1 is associated with a neurodevelopmental disorder: autosomal dominant mental retardation with language impairment with or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69da106eb7d887ef954fbedf244e7fee
https://doi.org/10.1055/s-0043-1767731
https://doi.org/10.1055/s-0043-1767731
Autor:
Mokryun L. Baek, Junegoo Lee, Katherine E. Pendleton, Mariah J. Berner, Emily B. Goff, Lin Tan, Sara A. Martinez, Iqbal Mahmud, Tao Wang, Matthew D. Meyer, Bora Lim, James P. Barrish, Weston Porter, Philip L. Lorenzi, Gloria V. Echeverria
Publikováno v:
Oncogene
Neoadjuvant chemotherapy (NACT) used for triple negative breast cancer (TNBC) eradicates tumors in approximately 45% of patients. Unfortunately, TNBC patients with substantial residual cancer burden have poor metastasis free and overall survival rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafa58e4c0d1f2889d32411063d87891
https://europepmc.org/articles/PMC10069007/
https://europepmc.org/articles/PMC10069007/
Autor:
Ajay K. Nooka, Samuel S. McCachren, Vikas Gupta, Sagar Lonial, Kavita M. Dhodapkar, Stephen M. Ansell, Lawrence H. Boise, Leonard T. Heffner, Julia Manalo, Akhilesh Kaushal, Allison R. Carr, Jonathan L. Kaufman, Nisha Joseph, Craig C. Hofmeister, Katherine E. Pendleton, Madhav V. Dhodapkar, Benjamin G. Barwick
Publikováno v:
Blood Cancer Discov
Waldenstrom macroglobulinemia (WM) and its precursor IgM gammopathy are distinct disorders characterized by clonal mature IgM-expressing B-cell outgrowth in the bone marrow. Here, we show by high-dimensional single-cell immunogenomic profiling of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e0587f122c1c75c80687d773600869
https://doi.org/10.1158/2643-3230.bcd-21-0043
https://doi.org/10.1158/2643-3230.bcd-21-0043
Autor:
Mokryun L. Baek, Junegoo Lee, Katherine E. Pendleton, Mariah J. Berner, Emily B. Goff, Lin Tan, Sara A. Martinez, Tao Wang, Matthew D. Meyer, Bora Lim, James P. Barrish, Weston Porter, Philip L. Lorenzi, Gloria V. Echeverria
Neoadjuvant chemotherapy (NACT) used for triple negative breast cancer (TNBC) eradicates tumors in approximately 45% of patients. Unfortunately, TNBC patients with substantial residual cancer burden have poor metastasis free and overall survival rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::717625ad35b5c6c96520bf5e771ec8c7
https://doi.org/10.1101/2022.02.25.481996
https://doi.org/10.1101/2022.02.25.481996