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pro vyhledávání: '"Katherine E. Cantwell"'
Autor:
Katherine E. Cantwell, R. Woodrow Setzer, Keith A. Houck, Stephen S. Ferguson, Richard S. Judson, Barbara A. Wetmore, Melvin E. Andersen, John F. Wambaugh, Mark A. Sochaski, Brittany Allen, Harvey J. Clewell, Russell S. Thomas, Cory L. Strope, Edward L. LeCluyse
Publikováno v:
Toxicological Sciences
We previously integrated dosimetry and exposure with high-throughput screening (HTS) to enhance the utility of ToxCast HTS data by translating in vitro bioactivity concentrations to oral equivalent doses (OEDs) required to achieve these levels intern
Autor:
Katherine E. Cantwell, Russell S. Thomas, Debra K. Layko, Darol E. Dodd, Gabrielle A. Willson
Publikováno v:
International Journal of Toxicology. 32:358-367
Female F344 rats were exposed to anthraquinone (AQ) by dietary feed at concentrations of 0, 50, 150, 469, 938, 1875, or 3750 ppm for 2 or 13 weeks. End points evaluated included clinical observations, body weights, serum chemistry, blood AQ, gross pa
Autor:
Katherine E. Cantwell, Gabrielle A. Willson, Darol E. Dodd, Russell S. Thomas, Debra K. Layko
Publikováno v:
Environmental toxicology and pharmacology. 36(3)
Male F344 rats were exposed to potassium bromate (KBrO 3 ) in drinking water at concentrations of 0, 5, 20, 100, 200, or 400 mg/L for 2 or 13 weeks. Endpoints evaluated included clinical observations, body weights, serum chemistry, gross pathology, o