Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katherine E. Bujold"'
Autor:
François Halloy, Annabelle Biscans, Katherine E. Bujold, Alexandre Debacker, Alyssa C. Hill, Aurélie Lacroix, Olivia Luige, Roger Strömberg, Linda Sundstrom, Jörg Vogel, Alice Ghidini
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 313-332 (2022)
RNA-based therapeutics are emerging as a powerful platform for the treatment of multiple diseases. Currently, the two main categories of nucleic acid therapeutics, antisense oligonucleotides and small interfering RNAs (siRNAs), achieve their therapeu
Externí odkaz:
https://doaj.org/article/cd8fb0a6285b407a8a63465d0c07a69f
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 815-822 (2020)
Externí odkaz:
https://doaj.org/article/67b76e3adc7844fcbc5e35e322f6fc43
Autor:
Caroline D. Kusmierz, Chad A. Mirkin, Max E Distler, Michael Evangelopoulos, Katherine E. Bujold, Michelle H. Teplensky
Publikováno v:
J Am Chem Soc
Herein, a method for synthesizing and utilizing DNA dendrons to deliver biomolecules to living cells is reported. Inspired by high-density nucleic acid nanostructures, such as spherical nucleic acids, we hypothesized that small clusters of nucleic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544968a4d6c5ff332b3dad682c2c619e
https://europepmc.org/articles/PMC8582297/
https://europepmc.org/articles/PMC8582297/
Publikováno v:
Journal of the American Chemical Society. 141:20171-20176
A new method for synthesizing deoxynucleic guanidine (DNG) oligonucleotides that uses iodine as a mild and inexpensive coupling reagent is reported. This method eliminates the need for the toxic mercury salts and pungent thiophenol historically used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ea3ba1e3d76d60234d00a7faf38ce1
https://doi.org/10.1021/jacs.9b09937
https://doi.org/10.1021/jacs.9b09937
Autor:
Devleena Samanta, Chad A. Mirkin, Aysenur Iscen, Katherine E. Bujold, Christine R. Laramy, Sasha B. Ebrahimi, George C. Schatz
Publikováno v:
Journal of the American Chemical Society. 141:19973-19977
Nanoparticles functionalized with DNA can assemble into ordered superlattices with defined crystal habits through programmable DNA “bonds”. Here, we examine the interactions of multivalent cations with these DNA bonds as a chemical approach for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73009961130bdd1e3e9096dc4b108ecb
https://doi.org/10.1021/jacs.9b09900
https://doi.org/10.1021/jacs.9b09900
Publikováno v:
Journal of the American Chemical Society. 141:11827-11831
Two DNA-cross-linking reagents, bis-chloroethylnitrosourea and 8-methoxypsoralen, are used to covalently cross-link interstrand base pairs in DNA bonds that, in part, define colloidal crystals engineered with DNA. The irreversible linkages formed inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f9187f4cf67bd9e459841c69f65835
https://doi.org/10.1021/jacs.9b06106
https://doi.org/10.1021/jacs.9b06106
Publikováno v:
Curr Protoc Nucleic Acid Chem
This protocol describes a method based on iodine and a base as mild coupling reagents to synthetize deoxyribonucleic guanidines (DNGs)-oligodeoxynucleotide analogues with a guanidine backbone. DNGs display unique properties, such as high cellular upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617307615c1d56982bbe1eda31a06a12
https://europepmc.org/articles/PMC7373344/
https://europepmc.org/articles/PMC7373344/
Publikováno v:
Chem. 4:495-521
Summary Over the past four decades, the field of structural DNA nanotechnology has evolved into an accessible approach to generating DNA nanostructures with precise control of size, geometry, and presentation of ligands. Moreover, the biocompatibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e0cf3da184b33b95c9c9c04ae03da4a
https://doi.org/10.1016/j.chempr.2018.02.005
https://doi.org/10.1016/j.chempr.2018.02.005
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992195
DNA nanotechnology enables the design and assembly of DNA nanostructures with unprecedented control over their size and shape. Additionally, the programmable base-pairing alphabet of DNA allows the incorporation of responsive units within these DNA n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c876419091013eea47400061213b6b
https://doi.org/10.1007/978-1-4939-9220-1_6
https://doi.org/10.1007/978-1-4939-9220-1_6
Autor:
Karina M. M. Carneiro, Lawrence Panasci, Hanadi F. Sleiman, Joel Neves Briard, Lilian Amrein, Antoine G. Godin, Paul W. Wiseman, Thomas G. W. Edwardson, Graham D. Hamblin, Johans Fakhoury, Katherine E. Bujold
Publikováno v:
Chem. Sci.. 5:2449-2455
Here, we demonstrate a new approach for the design and assembly of a dynamic DNA cube with an addressable cellular uptake profile. This cube can be selectively unzipped from a 3D to a flat two-dimensional structure in the presence of a specific nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda991a911c66029abce67df7dfb7c8d
https://doi.org/10.1039/c4sc00646a
https://doi.org/10.1039/c4sc00646a