Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Katherine E. Augustyn"'
Autor:
Christopher E Heise, Jeremy Murray, Katherine E Augustyn, Brandon Bravo, Preeti Chugha, Frederick Cohen, Anthony M Giannetti, Paul Gibbons, Rami N Hannoush, Brian R Hearn, Priyadarshini Jaishankar, Cuong Q Ly, Kinjalkumar Shah, Karen Stanger, Micah Steffek, Yinyan Tang, Xianrui Zhao, Joseph W Lewcock, Adam R Renslo, John Flygare, Michelle R Arkin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50864 (2012)
Inhibition of caspase-6 is a potential therapeutic strategy for some neurodegenerative diseases, but it has been difficult to develop selective inhibitors against caspases. We report the discovery and characterization of a potent inhibitor of caspase
Externí odkaz:
https://doaj.org/article/86e58beea90d4df59b4e81e29a6f24b6
Publikováno v:
Proceedings of the National Academy of Sciences. 104:18907-18912
Charge transport (CT) through the DNA base pairs provides a means to promote redox reactions at a remote site and potentially to effect signaling between molecules bound to DNA. Here we describe the oxidation of a cell-cycle regulatory protein, p53,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a539542f69fa371570ab9e1aa84b5fb
https://doi.org/10.1073/pnas.0709326104
https://doi.org/10.1073/pnas.0709326104
Publikováno v:
Biochemistry. 45:5039-5047
The fluorescent adenosine analogue 4-amino-8-(2-deoxy-beta-d-ribofuranosyl)-5'-O-dimethoxytrityl-6-methyl-7(8H)-pteridone (6MAP) has been used to perform residue specific analyses of DNA A-tracts during the premelting transition. DNA A-tracts, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98893bf20254a630ddee285c017e776b
https://doi.org/10.1021/bi0518343
https://doi.org/10.1021/bi0518343
Publikováno v:
Angewandte Chemie International Edition. 46:5731-5733
Charging along: DNA-mediated charge transport across adenine tracts is monitored by using a probe interior to the bridge (N^6-cyclopropyladenine (^(CP)A), shown in red). This trap was incorporated serially across the bridge and could be oxidized by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fbf1f9864634f1b1ebc3296bb0de49
https://doi.org/10.1002/anie.200701522
https://doi.org/10.1002/anie.200701522
Publikováno v:
Angewandte Chemie. 119:5833-5835
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95977668d96451db5173f8a411cfb51c
https://doi.org/10.1002/ange.200701522
https://doi.org/10.1002/ange.200701522
Autor:
Yinyan Tang, Cuong Ly, Karen Stanger, John A. Flygare, Priyadarshini Jaishankar, Kinjalkumar Shah, Frederick Cohen, Joseph W. Lewcock, Micah Steffek, Rami N. Hannoush, Xianrui Zhao, Katherine E. Augustyn, Preeti Chugha, Jeremy Murray, Brian R. Hearn, Paul Gibbons, Anthony M. Giannetti, Brandon J. Bravo, Christopher E. Heise, Adam R. Renslo, Michelle R. Arkin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50864 (2012)
PLoS ONE
PLoS ONE
Inhibition of caspase-6 is a potential therapeutic strategy for some neurodegenerative diseases, but it has been difficult to develop selective inhibitors against caspases. We report the discovery and characterization of a potent inhibitor of caspase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a3eb9e417122b5dfc1f6a3db4eb092
http://europepmc.org/articles/PMC3515450?pdf=render
http://europepmc.org/articles/PMC3515450?pdf=render
Publikováno v:
Wiley Encyclopedia of Chemical Biology
Here we describe studies of metallointercalators bound to DNA. These octahedral transition metal complexes primarily bind noncovalently by stacking within the DNA helix. Given the rich photophysics and photochemistry of the ruthenium and rhodium comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a695fae8a0d56368ec0cbee08cc8dd
https://doi.org/10.1002/9780470048672.wecb328
https://doi.org/10.1002/9780470048672.wecb328
A novel tris heteroleptic dipyridophenazine complex of ruthenium(II), [{Ru(phen)(dppz)(bpy‘-his)}{Ru(NH_3)_5}]^(5+), containing a covalently tethered ruthenium pentammine quencher coordinated through a bridging histidine has been synthesized and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6460a2413e48184e92b1a2e1ff8758
https://resolver.caltech.edu/CaltechAUTHORS:20160302-071129129
https://resolver.caltech.edu/CaltechAUTHORS:20160302-071129129
Publikováno v:
Angewandte Chemie International Edition. 46:5634-5634
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad49da2a077f21530e2addd291615e0c
https://doi.org/10.1002/anie.200790144
https://doi.org/10.1002/anie.200790144
Publikováno v:
Angewandte Chemie. 119:5732-5732
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd6c5cdff24ad272ae63808d55da4e9c
https://doi.org/10.1002/ange.200790144
https://doi.org/10.1002/ange.200790144