Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Katherine E, Sloan"'
Autor:
Lukas Brüning, Philipp Hackert, Roman Martin, Jimena Davila Gallesio, Gerald Ryan R. Aquino, Henning Urlaub, Katherine E. Sloan, Markus T. Bohnsack
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Pre-ribosomes undergo numerous structural rearrangements during their assembly. Here the authors identify the binding sites of three essential RNA helicases on pre-ribosomal particles, enabling them to provide insights into the structural and composi
Externí odkaz:
https://doaj.org/article/60281cffa46941bcbffe87e438136b67
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 237-247 (2013)
Several proto-oncogenes and tumor suppressors regulate the production of ribosomes. Ribosome biogenesis is a major consumer of cellular energy, and defects result in p53 activation via repression of mouse double minute 2 (MDM2) homolog by the ribosom
Externí odkaz:
https://doaj.org/article/c0ceca099e5442e7b3fcc741f4dc837d
Autor:
Maksim V. Sednev, Volodymyr Mykhailiuk, Priyanka Choudhury, Julia Halang, Katherine E. Sloan, Markus T. Bohnsack, Claudia Höbartner
Publikováno v:
Angewandte Chemie. 130:15337-15341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc8fc45d8a83fd3cb2a3ef736d80805
https://doi.org/10.1002/ange.201808745
https://doi.org/10.1002/ange.201808745
Autor:
Katherine E. Sloan, Markus T. Bohnsack
Publikováno v:
Trends in Biochemical Sciences. 43:237-250
RNA helicases are critical regulators at the nexus of multiple pathways of RNA metabolism, and in the complex cellular environment, tight spatial and temporal regulation of their activity is essential. Dedicated protein cofactors play key roles in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbff1c244a638f1704563dc58c1fa8d8
https://doi.org/10.1016/j.tibs.2018.02.001
https://doi.org/10.1016/j.tibs.2018.02.001
Autor:
Jens Kretschmer, Katherine E. Sloan, Ahmed S. Warda, Namit Ranjan, Charlotte Blessing, Claudia Höbartner, Marina V. Rodnina, Peter Rehling, Sven Dennerlein, Markus T. Bohnsack, Benedikt Hübner, Sara Haag, Jan Seikowski
Publikováno v:
The EMBO Journal
Mitochondrial gene expression uses a non‐universal genetic code in mammals. Besides reading the conventional AUG codon, mitochondrial (mt‐)tRNAMet mediates incorporation of methionine on AUA and AUU codons during translation initiation and on AUA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db467585bea1ed14b4fbff1bf692c26
https://doi.org/10.15252/embj.201694885
https://doi.org/10.15252/embj.201694885
Autor:
Katherine E. Sloan, Markus T. Bohnsack
Publikováno v:
Biological chemistryReferences. 399(11)
Modifications in cellular RNAs have emerged as key regulators of all aspects of gene expression, including pre-mRNA splicing. During spliceosome assembly and function, the small nuclear RNAs (snRNAs) form numerous dynamic RNA-RNA and RNA-protein inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d58d8b605ae38e55b8fd9634c09ff0
https://pubmed.ncbi.nlm.nih.gov/29908124
https://pubmed.ncbi.nlm.nih.gov/29908124
Autor:
Henning Urlaub, Markus T. Bohnsack, Lukas Brüning, Jimena Davila Gallesio, Roman Martin, Gerald Ryan R. Aquino, Philipp Hackert, Katherine E. Sloan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Production of eukaryotic ribosomal subunits is a highly dynamic process; pre-ribosomes undergo numerous structural rearrangements that establish the architecture present in mature complexes and serve as key checkpoints, ensuring the fidelity of ribos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f284c3887453c4b21755b37b5acf942
https://pubmed.ncbi.nlm.nih.gov/30568249
https://pubmed.ncbi.nlm.nih.gov/30568249
Autor:
Priyanka Choudhury, Volodymyr Mykhailiuk, Maksim V. Sednev, Katherine E. Sloan, Markus T. Bohnsack, Julia Halang, Claudia Höbartner
Publikováno v:
Angewandte Chemie International Edition
Deoxyribozymes are synthetic enzymes made of DNA that can catalyze the cleavage or formation of phosphodiester bonds and are useful tools for RNA biochemistry. Here we report new RNA-cleaving deoxyribozymes to interrogate the methylation status of ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d3dc735829925e37f0a270558b6510
Autor:
Henning Urlaub, Jens Kretschmer, Katherine E. Sloan, Philipp Hackert, Claudia Höbartner, Ahmed S. Warda, Christof Lenz, Markus T. Bohnsack
Publikováno v:
EMBO Reports
N6-methyladenosine (m6A) is a highly dynamic RNA modification that has recently emerged as a key regulator of gene expression. While many m6A modifications are installed by the METTL3-METTL14 complex, others appear to be introduced independently, imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112a49e1094a59eac1d3c941eab88f4b
https://hdl.handle.net/11858/00-001M-0000-002E-1983-511858/00-001M-0000-002E-2CB2-211858/00-001M-0000-002E-2CB4-D11858/00-001M-0000-002E-2CB5-B11858/00-001M-0000-002E-2CB3-F11858/00-001M-0000-002E-2CB7-711858/00-001M-0000-002E-2CB6-9
https://hdl.handle.net/11858/00-001M-0000-002E-1983-511858/00-001M-0000-002E-2CB2-211858/00-001M-0000-002E-2CB4-D11858/00-001M-0000-002E-2CB5-B11858/00-001M-0000-002E-2CB3-F11858/00-001M-0000-002E-2CB7-711858/00-001M-0000-002E-2CB6-9
Autor:
Jens, Kretschmer, Harita, Rao, Philipp, Hackert, Katherine E, Sloan, Claudia, Höbartner, Markus T, Bohnsack
Publikováno v:
RNA (New York, N.Y.). 24(10)
N6-methyladenosine (m6A) modifications in RNAs play important roles in regulating many different aspects of gene expression. While m6As can have direct effects on the structure, maturation, or translation of mRNAs, such modifications can also influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d19cbfcd3d7014b7b8da8741f5e7b85e
https://pubmed.ncbi.nlm.nih.gov/29970596
https://pubmed.ncbi.nlm.nih.gov/29970596