Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Katherine Belecki"'
Autor:
D. Tyler McQuade, Katherine Belecki, Caleb J. Kong, B. Frank Gupton, Julie B. Manley, Saeed Ahmad, Daniel Rivalti, Rudy Krack, Jesús Alcázar, Eric C. Yu, Jenson Verghese
Publikováno v:
Green Chemistry. 19:2986-2991
Access to affordable medications continues to be one of the most pressing issues for the treatment of disease in developing countries. For many drugs, synthesis of the active pharmaceutical ingredient (API) represents the most financially important a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1874817cc48e5f5e24dfd7771f2c29e0
https://doi.org/10.1039/c7gc00937b
https://doi.org/10.1039/c7gc00937b
Publikováno v:
Green Processing and Synthesis, Vol 4, Iss 3, Pp 241-246 (2015)
An efficient, sustainable, and continuous method for the preparation of graphene supported palladium nanoparticles (Pd/G) has been developed using microwave irradiation as a heating source for the metal deposition process. The Pd/G produced from this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98328de09734867184ae9eb14b6c7e9
https://doaj.org/article/4dc761e14a37493585267c363bf5ffde
https://doaj.org/article/4dc761e14a37493585267c363bf5ffde
Autor:
Daniel Fisher, Saeed Ahmad, Yuan Yang, Katherine Belecki, Caleb J. Kong, B. Frank Gupton, Bimbisar Desai
Publikováno v:
Bioorganicmedicinal chemistry. 25(23)
The efficiency gains produced by continuous-flow systems in conducting photochemical transformations have been extensively demonstrated. Recently, these systems have been used in developing safe and efficient methods for photo-oxidations using single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7822990886eb98d13b9b155fb80395
https://pubmed.ncbi.nlm.nih.gov/29054711
https://pubmed.ncbi.nlm.nih.gov/29054711
Publikováno v:
Journal of Flow Chemistry. 5:145-147
A highly efficient continuous synthesis has been developed for telmisartan, the active ingredient in the antihypertensive drug, Micardis. This synthetic route employs a convergent strategy that requires no intermediate purifications or solvent exchan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c354e40b3a651d662f5d9e3fa6e19d9
https://doi.org/10.1556/jfc-d-15-00002
https://doi.org/10.1556/jfc-d-15-00002
Autor:
Katherine Belecki, Craig A. Townsend
Publikováno v:
Angewandte Chemie International Edition. 51:11316-11319
The enediyne natural products exhibit potent antitumor and antibiotic activity in addition to displaying structural features that are quite remarkable both as a synthetic challenge and a biosynthetic enigma.[1] Members of this group typically incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ead390e9faeaa23dc3e4a0ed9ab9777
https://doi.org/10.1002/anie.201206462
https://doi.org/10.1002/anie.201206462
Autor:
Richard Todd Bibart, James E. Phillips, Cliff Meltz, Karl Ng, Katherine Belecki, Michael G. Vetelino, Martin A. Berliner, David H. Brown Ripin
Publikováno v:
Organic Process Research & Development. 11:754-761
The synthesis of zwitterionic CP-865,569 by three different synthetic routes is described. The first two routes differ in the method of introducing the sulfonic acid at the penultimate step: by sulfite displacement of a benzylic chloride and by oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::025de42226590f3748948eed7c22aec0
https://doi.org/10.1021/op7000386
https://doi.org/10.1021/op7000386
Autor:
B. Frank Gupton, Katherine Belecki
Publikováno v:
Green Chemistry Strategies for Drug Discovery ISBN: 9781849739610
The ability to produce a broad range of pharmacophores is an enabling element of the drug discovery process. Continuous chemical processing offers the opportunity to access synthons that are unavailable through traditional batch methods. Herein we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9291cc27d6aeeadd09c3f60c2dda81
https://doi.org/10.1039/9781782622659-00127
https://doi.org/10.1039/9781782622659-00127
Publikováno v:
ChemInform. 46
A direct and efficient total synthesis is developed for telmisartan (I), a widely prescribed treatment for hypertension.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d65788dbea5fad5e1019c8a383425da
https://doi.org/10.1002/chin.201526159
https://doi.org/10.1002/chin.201526159
Publikováno v:
The Journal of organic chemistry. 80(3)
A direct and efficient total synthesis has been developed for telmisartan, a widely prescribed treatment for hypertension. This approach brings together two functionalized benzimidazoles using a high-yielding Suzuki reaction that can be catalyzed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd77e73fd5c9c104e50fac1aaa051d5
https://pubmed.ncbi.nlm.nih.gov/25522005
https://pubmed.ncbi.nlm.nih.gov/25522005
Autor:
Katherine Belecki, Martin A. Berliner
Publikováno v:
The Journal of Organic Chemistry. 70:9618-9621
Zinc(II) salts catalyze the reaction between acetals and acid halides to provide haloalkyl ethers in near-quantitative yield. Reactions from millimole to mole scale are typically complete in 1−4 h with 0.01 mol % catalyst. The solutions of haloalky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90afbad1ba4a81a86b83fd1377e64250
https://doi.org/10.1021/jo051344g
https://doi.org/10.1021/jo051344g