Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Katherine B Hammond"'
Autor:
Benjamin J Burwitz, Daniel Malouli, Benjamin N Bimber, Jason S Reed, Abigail B Ventura, Meaghan H Hancock, Luke S Uebelhoer, Amruta Bhusari, Katherine B Hammond, Renee G Espinosa Trethewy, Alex Klug, Alfred W Legasse, Michael K Axthelm, Jay A Nelson, Byung S Park, Daniel N Streblow, Scott G Hansen, Louis J Picker, Klaus Früh, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006014 (2016)
Cytomegaloviruses (CMV) are highly species-specific due to millennia of co-evolution and adaptation to their host, with no successful experimental cross-species infection in primates reported to date. Accordingly, full genome phylogenetic analysis of
Externí odkaz:
https://doaj.org/article/7f89ac2e54d24ee7a16db764f546ae92
Autor:
Glen M Chew, Tsuyoshi Fujita, Gabriela M Webb, Benjamin J Burwitz, Helen L Wu, Jason S Reed, Katherine B Hammond, Kiera L Clayton, Naoto Ishii, Mohamed Abdel-Mohsen, Teri Liegler, Brooks I Mitchell, Frederick M Hecht, Mario Ostrowski, Cecilia M Shikuma, Scott G Hansen, Mark Maurer, Alan J Korman, Steven G Deeks, Jonah B Sacha, Lishomwa C Ndhlovu
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005349 (2016)
HIV infection induces phenotypic and functional changes to CD8+ T cells defined by the coordinated upregulation of a series of negative checkpoint receptors that eventually result in T cell exhaustion and failure to control viral replication. We repo
Externí odkaz:
https://doaj.org/article/98d1b0911eb74042a13b8e84449dee0c
Autor:
Shaheed A. Abdulhaqq, Justin M. Greene, Aravind Asokan, Katherine B. Hammond, Jochen M. Wettengel, Gabriela M. Webb, Alfred W. Legasse, William F. Sutton, Jonah B. Sacha, Marc Ringelhan, Marvin M. Festag, Thomas Jacob, Chunkyu Ko, Reed A. Norris, Sven Moller-Tank, Martin A. Mück-Häusl, Tania Q. Vu, Byung Park, Nancy L. Haigwood, Mina Northrup, Alex Klug, Benjamin N. Bimber, Benjamin J. Burwitz, Ulrike Protzer, Tonya Swanson, Knud Esser, Helen L. Wu, Jason S. Reed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nat. Commun. 8:2146 (2017)
Nature Communications
Nat. Commun. 8:2146 (2017)
Hepatitis B virus (HBV) is a major global health concern, and the development of curative therapeutics is urgently needed. Such efforts are impeded by the lack of a physiologically relevant, pre-clinical animal model of HBV infection. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb335eb7fa39e5edb40f6267779a7a8
http://link.springer.com/article/10.1038/s41467-017-01953-y
http://link.springer.com/article/10.1038/s41467-017-01953-y
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose AMD is the leading cause of human vision loss after 65 years of age. Several mechanisms have been proposed: (1) age-related failure of the choroidal vasculature leads to loss of RPE; (2) RPE dysfunctions due to accumulation of phagocytized, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1622edb42ea2aa1eb8b59182e923ddb0
http://europepmc.org/articles/PMC6110128
http://europepmc.org/articles/PMC6110128
Autor:
Shaheed A. Abdulhaqq, Jonah B. Sacha, Scott G. Hansen, Katherine B. Hammond, Jason S. Reed, Klaus Früh, Helen L. Wu, Michael K. Axthelm, Byung Park, Louis J. Picker, Alfred W. Legasse, Aravind Asokan, John B. Schell
Major histocompatibility complex E (MHC-E) is a highly conserved nonclassical MHC-Ib molecule that tightly binds peptides derived from leader sequences of classical MHC-Ia molecules for presentation to natural killer cells. However, MHC-E also binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5558f1aa73cede619954ecf2eb531258
https://europepmc.org/articles/PMC6744250/
https://europepmc.org/articles/PMC6744250/
Autor:
David H. O’Connor, Lina Gao, Alfred W. Legasse, Justin M. Greene, Byung Park, Fidel Ferrer, Roger W. Wiseman, Simon Brackenridge, Katherine B. Hammond, Nicholas J. Maness, Scott G. Hansen, Benjamin N. Bimber, Benjamin J. Burwitz, Michael K. Axthelm, Jason S. Reed, Shaheed A. Abdulhaqq, Andrew J. McMichael, Helen L. Wu, Louis J. Picker, Jonah B. Sacha, Colette M. Hughes, Gabriela M. Webb
MHC-E is a highly conserved nonclassical MHC class Ib molecule that predominantly binds and presents MHC class Ia leader sequence-derived peptides for NK cell regulation. However, MHC-E also binds pathogen-derived peptide Ags for presentation to CD8+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd4e0f5da2ce5db7965045f96ee17b6
https://doi.org/10.4049/jimmunol.1700841
https://doi.org/10.4049/jimmunol.1700841
Autor:
Charles R. Thomas, Jeffrey J. Stanton, Jason S. Reed, Gabrielle Meyers, Mina Northrup, Katherine B. Hammond, Helen L. Wu, Stephanie L. Junell, Anne D. Lewis, Shaheed A. Abdulhaqq, Paul Kievit, Benjamin J. Burwitz, Theodore R. Hobbs, Alfred W. Legasse, Lauren D. Martin, W Laub, Gabriela M. Webb, Betsy Ferguson, Rebecca M. Ducore, Michael K. Axthelm, Justin M. Greene, Jonah B. Sacha, Lois M. A. Colgin, Tonya Swanson, Richard T. Maziarz, Angela Panoskaltsis-Mortari, Christine Shriver-Munsch, Benjamin N. Bimber, Rhonda MacAllister
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Allogeneic hematopoietic stem cell transplantation (HSCT) is a critically important therapy for hematological malignancies, inborn errors of metabolism, and immunodeficiency disorders, yet complications such as graft-vs.-host disease (GvHD) limit sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1179c9825d03ba05b2fb74382516192
https://doi.org/10.1038/s41467-017-01631-z
https://doi.org/10.1038/s41467-017-01631-z
Autor:
Shannon L. Planer, Katherine B. Hammond, Benjamin J. Burwitz, Jonah B. Sacha, Merete A. Ohme, Adam J. Ericsen, Yoram Richter, Alfred W. Legasse, Gershon Golomb, Jason S. Reed
Publikováno v:
Journal of Leukocyte Biology
Nonhuman primates are critical animal models for the study of human disorders and disease and offer a platform to assess the role of immune cells in pathogenesis via depletion of specific cellular subsets. However, this model is currently hindered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22aa79195ee89b9b24e18b1588ea4b2e
https://doi.org/10.1189/jlb.5ta0713-373r
https://doi.org/10.1189/jlb.5ta0713-373r
Autor:
Benjamin N. Bimber, Katherine B. Hammond, Tetsuro Matano, Enrique J. León, Masaru Yokoyama, Thomas C. Friedrich, Laura Newman, Jason S. Reed, Nicholas J. Maness, Hironori Sato, Jonah B. Sacha, Francesca A. Nimiyongskul, David H. O’Connor, Benjamin J. Burwitz, Helen L. Wu
Publikováno v:
Journal of Virology. 88:3598-3604
Compensatory mutations offset fitness defects resulting from CD8 + T lymphocyte (CD8 TL )-mediated escape, but their impact on viral evolution following transmission to naive hosts remains unclear. Here, we investigated the reversion kinetics of Gag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251e2ddc804a0bee0f8d6c5c404e2ea1
https://doi.org/10.1128/jvi.03304-13
https://doi.org/10.1128/jvi.03304-13
Publikováno v:
Current Eye Research. 39:421-424
Purpose/Aim: Calpain proteases are known to be involved in retinal cell death in animal models. The purpose of the present study was to test for calpain activation in human retinas cultured under hypoxic conditions.Materials and Methods: Calpain acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133dd3d1578769335af080b3089ccac7
https://doi.org/10.3109/02713683.2013.845225
https://doi.org/10.3109/02713683.2013.845225