Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Katherine A. Knutson"'
Publikováno v:
HGG Advances, Vol 3, Iss 4, Pp 100144- (2022)
Summary: Genome-wide association studies (GWASs) have successfully identified many genetic variants and risk loci for complex traits and common diseases in the last 15 years. However, these identified variants, in general, can explain only a small to
Externí odkaz:
https://doaj.org/article/6573a2ea0c144b8ea7e875eb16e4324f
Autor:
Alexa A. Pragman, Katherine A. Knutson, Trevor J. Gould, Richard E. Isaacson, Cavan S. Reilly, Chris H. Wendt
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Chronic obstructive pulmonary disease (COPD) frequent exacerbators (FE) suffer increased morbidity and mortality compared to infrequent exacerbators (IE). The association between the oral and sputum microbiota and exacerbation phe
Externí odkaz:
https://doaj.org/article/8ca42359042c460f8f7bc80915e88bdb
Publikováno v:
NeuroImage, Vol 223, Iss , Pp 117347- (2020)
Recent evidence suggests the existence of many undiscovered heritable brain phenotypes involved in Alzheimer’s Disease (AD) pathogenesis. This finding necessitates methods for the discovery of causal brain changes in AD that integrate Magnetic Reso
Externí odkaz:
https://doaj.org/article/1df078acbf59410a8ecf1ee7f7949e6e
Autor:
Katherine A Knutson, Wei Pan
Publikováno v:
Human Molecular Genetics. 32:1237-1251
The Transcriptome-Wide Association Study (TWAS) is a widely used approach which integrates gene expression and Genome Wide Association Study (GWAS) data to study the role of cis-regulated gene expression (GEx) in complex traits. However, the genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb86437f7c4dcee210c88f94b01e966
https://doi.org/10.1093/hmg/ddac247
https://doi.org/10.1093/hmg/ddac247
Autor:
Alexa A Pragman, Katherine A Knutson, Trevor J Gould, Shane W Hodgson, Richard E Isaacson, Cavan S Reilly, Chris H Wendt
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219962 (2019)
BackgroundChronic obstructive pulmonary disease (COPD) is an inflammatory lung disorder associated with lung microbiome dysbiosis. Although the upper airway microbiome is the source of the lung microbiome, the relationships between the oral, nasal, a
Externí odkaz:
https://doaj.org/article/8d4ffefc53a64e1996c162930124d0de
Publikováno v:
Hum Mol Genet
Transcriptome-wide association studies (TWAS) integrate genome-wide association study (GWAS) data with gene expression (GE) data to identify (putative) causal genes for complex traits. There are two stages in TWAS: in Stage 1, a model is built to imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5145ded277d000b7ecc152dfbe153767
https://doi.org/10.1093/hmg/ddac015
https://doi.org/10.1093/hmg/ddac015
Publikováno v:
Psychiatric Services. 72:943-950
Multiple barriers exist to accessing behavioral health care, and several are related to payment. The national shortage of behavioral health providers is exacerbated by their not joining health insurance networks, often shifting the cost of treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40473b5331844c05204b4b3edb048e45
https://doi.org/10.1176/appi.ps.202000386
https://doi.org/10.1176/appi.ps.202000386
Multivariate matched proportions (MMP) data appears in a variety of contexts including post-market surveillance of adverse events in pharmaceuticals, disease classification, and agreement between care providers. It consists of multiple sets of paired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7098ab39d0094bfff254f34b5e3bc5
Publikováno v:
C52. STUDIES IN BRONCHIECTASIS, HIV, AND LUNG MICROBIOME.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d14fcdd139a8832e03211c119d3fe8
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5411
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5411
Publikováno v:
Clinical Pediatrics. 57:5-10
Many children are treated for mental health disorders in primary care settings. The system of care (SOC) provides a framework for collaboration among pediatric mental health providers, but it is unclear if youth treated for mental health disorders in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7101d379cd82b1839c96b19241fb5e40
https://doi.org/10.1177/0009922817733740
https://doi.org/10.1177/0009922817733740