Výsledky vyhledávání - "Katherine A. Keller"

SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response

Autor: Jonathan P. Davies, Athira Sivadas, Katherine R. Keller, Richard J.H. Wojcikiewicz, Lars Plate

Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis pathways during infection through activation of stress-responsive signaling pathways such as the Unfolded Protein Response (UPR). The UPR regulates protein translation, increases p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67620732ae3b7899243d8eefbff52e20
https://doi.org/10.1101/2023.04.22.537917

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Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis

Autor: Caden G. Bonzerato, Katherine R. Keller, Jacqualyn J. Schulman, Xiaokong Gao, Laura M. Szczesniak, Richard J. H. Wojcikiewicz

Publikováno v: Frontiers in cell and developmental biology. 10

Controversy surrounds the cellular role of the Bcl-2 family protein Bok. On one hand, it has been shown that all endogenous Bok is bound to inositol 1,4,5-trisphosphate receptors (IP3Rs), while other data suggest that Bok can act as a pro-apoptotic m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d2aba5541cd761ed28bee0a3c0734d
https://pubmed.ncbi.nlm.nih.gov/36601536

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Mg/Ca ratios in ostracode genera Sarsicytheridea and Paracyprideis: A potential paleotemperature proxy for Arctic and subarctic continental shelf and slope waters

Autor: Katherine K. Keller, Thomas M. Cronin, Gary S. Dwyer, Jesse Farmer, Laura Gemery

Publikováno v: Marine Micropaleontology. 174:102035

We evaluate the potential utility of Mg/Ca in the ostracode genera Sarsicytheridea and Paracyprideis as a paleotemperature proxy for continental shelf and upper slope waters of the Arctic Ocean and adjacent seas. Using sediment core-top and surface s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::256cc31c2b60cb468fa48b74c6e785b6
https://doi.org/10.1016/j.marmicro.2021.102035

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Akademický článek

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Despite major drug discovery efforts, the therapeutic options for glioblastoma (GBM) remain inadequate. Here they analyze patient-derived xenograft model of GBM to quantitatively map distribution and cellular response to the EGFR inhibitor erlotinib,

Externí odkaz: https://doaj.org/article/17219987055045cbbd74e20d4356a523

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Gender, Myth, and Memory, Ethnic Continuity in Greek-American Narrative

Autor: Katherine Zepantis Keller

Publikováno v: MELUS. 20:47

The life of the immigrant was that of a man diverted by unexpected pressures away from the established channels of his existence. Separated, he was never capable of acting with the assurance of habit; always in motion, he could never rely upon roots

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ecc0dae6e0122512f961f0bf24c67d6
https://doi.org/10.2307/467742

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