Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Katherine A. Harvey"'
Autor:
Carol J. Fabian, Carola M. Zalles, Bruce F. Kimler, Debra K. Sullivan, Susan E. Carlson, Katherine E. Harvey, Shengqi Li, Brandon H. Hidaka
Supplemental Tables 1-5. Supplemental Table 1: comparison of fatty acid composition by cytologic atypia or not. Supplemental Table 2: Comparison of fatty acid composition of plasma phospholipids (PLs) by evidence of cytology atypia. Supplemental Tabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034616c84620be65efd7026a0797e623
https://doi.org/10.1158/1940-6207.22524702
https://doi.org/10.1158/1940-6207.22524702
Autor:
Greta E Weiss, Paul R Gilson, Tana Taechalertpaisarn, Wai-Hong Tham, Nienke W M de Jong, Katherine L Harvey, Freya J I Fowkes, Paul N Barlow, Julian C Rayner, Gavin J Wright, Alan F Cowman, Brendan S Crabb
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004670 (2015)
During blood stage Plasmodium falciparum infection, merozoites invade uninfected erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand binding events. Understanding each element in this process increases the pot
Externí odkaz:
https://doaj.org/article/1a1fe246a3be48d4bf55ff5da97ff1d3
Autor:
Kieran Cashin, Jasminka Sterjovski, Katherine L Harvey, Paul A Ramsland, Melissa J Churchill, Paul R Gorry
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109771 (2014)
The ability to determine coreceptor usage of patient-derived human immunodeficiency virus type 1 (HIV-1) strains is clinically important, particularly for the administration of the CCR5 antagonist maraviroc. The envelope glycoprotein (Env) determinan
Externí odkaz:
https://doaj.org/article/4286cc87351a4327acfdf16c2e6e080d
Autor:
Katherine Schiro Harvey
Publikováno v:
Nutrition in Kidney Disease ISBN: 9783030448578
Chronic kidney disease (CKD) is a worldwide public health problem and a progressive, debilitating condition. In the United States, it is estimated that 15% of the population have CKD, equivalent to 37 million Americans or one in seven adults. Most in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69038c7813f802e7c28d7b34fa37f57b
https://doi.org/10.1007/978-3-030-44858-5_14
https://doi.org/10.1007/978-3-030-44858-5_14
Autor:
Brendan S. Crabb, Katherine L. Harvey, Travis Clarke Beddoe, Jamie Rossjohn, Paul R. Gilson, Dene R. Littler, Hayley E Bullen
Publikováno v:
Journal of Biological Chemistry. 291:25375-25386
The ubiquitous second messenger cAMP mediates signal transduction processes in the malarial parasite that regulate host erythrocyte invasion and the proliferation of merozoites. In Plasmodium falciparum, the central receptor for cAMP is the single re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92a2db2d09d0934f4eb7157598f136e
https://doi.org/10.1074/jbc.m116.750174
https://doi.org/10.1074/jbc.m116.750174
Autor:
Paul R. Gilson, Boris Prinz, Brendan S. Crabb, David J. D. Wilson, Katherine L. Harvey, Melissa J. Buskes, Belinda M. Abbott
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:2389-2396
A series of isoquinolines have been evaluated in a homology model of Plasmodium falciparum Protein Kinase A ( Pf PKA) using molecular dynamics. Synthesis of these compounds was then undertaken to investigate their structure–activity relationships.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dfea40ccfc1ef46fa0420803d8935d
https://doi.org/10.1016/j.bmc.2016.03.048
https://doi.org/10.1016/j.bmc.2016.03.048
Autor:
Leslie W. Deady, Nathan J. O'Brien, Elliott D. Cope, Brendan S. Crabb, Belinda M. Abbott, Chamodi K. Gardhi, Greta E. Weiss, Melissa J. Buskes, Rebecca M. Christoff, Robabeh Kalhor, Paul R. Gilson, Boris Prinz, Dene R. Littler, Benjamin J. Richards, Katherine L. Harvey
Publikováno v:
Organic & Biomolecular Chemistry. 14:4617-4639
Central to malaria pathogenesis is the invasion of human red blood cells by Plasmodium falciparum parasites. Following each cycle of intracellular development and replication, parasites activate a cellular program to egress from their current host ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc507a46e38bcf23e43e61926e9a482e
https://doi.org/10.1039/c5ob02517f
https://doi.org/10.1039/c5ob02517f
Publikováno v:
International Journal for Parasitology. 44:853-857
Apicomplexan parasites are obligate intracellular pathogens that cause a host of human and animal diseases. These parasites have developed a universal mechanism of invasion involving formation of a ‘moving junction’ that provides a stable anchori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8062f45070cf45bf0c484b14981404
https://doi.org/10.1016/j.ijpara.2014.08.001
https://doi.org/10.1016/j.ijpara.2014.08.001
Autor:
Steffen Erkelenz, Conrad Kunick, Isabelle S Lucet, Dorothee Heincke, Tim W. Gilberger, Christian Doerig, Klemens Engelberg, Tobias Spielmann, Laura Biller, Ulrike Ruch, Paul R. Gilson, Brendan S. Crabb, Boris Prinz, Katherine L. Harvey, Louisa Wilcke
Publikováno v:
Scientific Reports
Central to the pathogenesis of malaria is the proliferation of Plasmodium falciparum parasites within human erythrocytes. Parasites invade erythrocytes via a coordinated sequence of receptor-ligand interactions between the parasite and host cell. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16640cd9026e18c035e2c47506eec231
https://doi.org/10.1038/srep34479
https://doi.org/10.1038/srep34479
Publikováno v:
International Journal for Parasitology. 42:567-573
Multiple and seemingly sequential interactions between parasite ligands and their receptors on host erythrocytes are an essential precursor to invasion by the obligate intracellular pathogen, Plasmodium falciparum. Consequently, identification and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd6afff16fd51ffc9dd77adad930c93
https://doi.org/10.1016/j.ijpara.2012.02.011
https://doi.org/10.1016/j.ijpara.2012.02.011