Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Katherine A. Graham-O'Regan"'
1
Akademický článek
Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist
Autor: Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs
Publikováno v: Hepatology Communications, Vol 2, Iss 7, Pp 821-835 (2018)
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic reso
Externí odkaz: https://doaj.org/article/3b4760b0fefd4d1697564907fb1c9f1f
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2
Akademický článek
Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy
Autor: Derek J. Erstad, Mozhdeh Sojoodi, Martin S. Taylor, Sarani Ghoshal, Allen A. Razavi, Katherine A. Graham-O'Regan, Nabeel Bardeesy, Cristina R. Ferrone, Michael Lanuti, Peter Caravan, Kenneth K. Tanabe, Bryan C. Fuchs
Publikováno v: Disease Models & Mechanisms, Vol 11, Iss 7 (2018)
Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics. Here, we describe surgic
Externí odkaz: https://doaj.org/article/fbee34e2fe41448db3848672115d105a
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7
(68)Ga-NODAGA-indole, an allysine-reactive positron emission tomography probe for molecular imaging of pulmonary fibrogenesis
Autor: Junfeng Wang, Peter Caravan, Bryan C. Fuchs, Eric Abston, Jessica Wahsner, Katherine A. Graham-O'Regan, Schirmer, Sui J, Pauline Désogère, Santos Ferreira Dd, Nicholas J. Rotile, Michael Lanuti
Oxidized collagen, wherein lysine residues are converted to the aldehyde allysine, is a universal feature of fibrogenesis, i.e. actively progressive fibrosis. Here we report the small molecule, allysine-binding positron emission tomography (PET) prob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93d7375e0cd24d865a00aa11baae1eb
https://europepmc.org/articles/PMC6494104/
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8
Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy
Autor: Allen Razavi, Cristina R. Ferrone, Derek J. Erstad, Katherine A. Graham-O'Regan, Kenneth K. Tanabe, Nabeel Bardeesy, Peter Caravan, Bryan C. Fuchs, Sarani Ghoshal, Michael Lanuti, Martin S. Taylor, Mozhdeh Sojoodi
Publikováno v: Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 7 (2018)
Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics. Here, we describe surgic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d330ee495297afe66bba02c6ba620d4
https://doi.org/10.1242/dmm.034793
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