Zobrazeno 1 - 10
of 513
pro vyhledávání: '"Katherine A White"'
Autor:
Vicki J Swier, Katherine A White, David K Meyerholz, Aude Chefdeville, Rajesh Khanna, Jessica C Sieren, Dawn E Quelle, Jill M Weimer
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228222 (2020)
Genetically modified swine disease models are becoming increasingly important for studying molecular, physiological and pathological characteristics of human disorders. Given the limited history of these model systems, there remains a great need for
Externí odkaz:
https://doaj.org/article/e64e186dece145d8bb800f4b1cc4ecb8
Autor:
Derek Timm, Jacob T Cain, Ryan D Geraets, Katherine A White, Seung Yon Koh, Tammy Kielian, David A Pearce, Michelle L Hastings, Jill M Weimer
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201470 (2018)
CLN3-Batten disease is a rare, autosomal recessive disorder involving seizures, visual, motor and cognitive decline, and premature death. The Cln3Δex7/8 mouse model recapitulates several phenotypic characteristics of the most common 1.02kb disease-a
Externí odkaz:
https://doaj.org/article/1d107ecde9b04446bdecf6b33b0ce7da
Autor:
Vicki J. Swier, Katherine A. White, Pedro L. Negrão de Assis, Tyler B. Johnson, Hannah G. Leppert, Mitchell J. Rechtzigel, David K. Meyerholz, Rebecca D. Dodd, Dawn E. Quelle, Rajesh Khanna, Christopher S. Rogers, Jill M. Weimer
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract Cognitive or motor impairment is common among individuals with neurofibromatosis type 1 (NF1), an autosomal dominant tumor‐predisposition disorder. As many as 70% of children with NF1 report difficulties with spatial/working memory, attent
Externí odkaz:
https://doaj.org/article/dcb502b067bb4af5b36833c1c551cbde
Autor:
Katherine E. White, Hannah L. Bailey, Barry S. Shaw, Philippine C. Geiszler, Raquel Mesquita-Ribeiro, Daniel Scott, Robert Layfield, Sébastien Serres
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Extracellular vesicles (EVs) are secreted by all cells in the CNS, including neurons and astrocytes. EVs are lipid membrane enclosed particles loaded with various bioactive cargoes reflecting the dynamic activities of cells of origin. In contrast to
Externí odkaz:
https://doaj.org/article/c3d8d0db27c640d6b61f09654f9f5c91
Magnetic resonance brain volumetry biomarkers of CLN2 Batten disease identified with miniswine model
Autor:
Kevin Knoernschild, Hans J. Johnson, Kimberly E. Schroeder, Vicki J. Swier, Katherine A. White, Takashi S. Sato, Christopher S. Rogers, Jill M. Weimer, Jessica C. Sieren
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease (Batten disease) is a rare pediatric disease, with symptom development leading to clinical diagnosis. Early diagnosis and effective tracking of disease progression are requi
Externí odkaz:
https://doaj.org/article/ae674f749002440bacb75763026cfd62
Autor:
Vicki J. Swier, Katherine A. White, Tyler B. Johnson, Xiaojun Wang, Jimin Han, David A. Pearce, Ruchira Singh, Arlene V. Drack, Wanda Pfeifer, Christopher S. Rogers, Jon J. Brudvig, Jill M. Weimer
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/3337fe76b208495abbbceb7bc70a4a23
Autor:
Tyler B. Johnson, Jon J. Brudvig, Shibi Likhite, Melissa A. Pratt, Katherine A. White, Jacob T. Cain, Clarissa D. Booth, Derek J. Timm, Samantha S. Davis, Brandon Meyerink, Ricardo Pineda, Cassandra Dennys-Rivers, Brian K. Kaspar, Kathrin Meyer, Jill M. Weimer
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
CLN3 disease, caused by biallelic mutations in the CLN3 gene, is a rare pediatric neurodegenerative disease that has no cure or disease modifying treatment. The development of effective treatments has been hindered by a lack of etiological knowledge,
Externí odkaz:
https://doaj.org/article/cb379df157064165b746745383d34428
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286053 (2023)
Given the predominance of the theory of planned behaviour (TPB) to represent the psychological determinants underlying people's charitable decisions, the present study synthesised the model's key relationships, using meta-analysis, and tested the pre
Externí odkaz:
https://doaj.org/article/84ae36e672d04671acc8b2dedee29acb
Autor:
David John Kavanagh, Jennifer Connolly, Jane Fisher, W Kim Halford, Kyra Hamilton, Leanne Hides, Jeannette Milgrom, Heather Rowe, Paul A Scuffham, Katherine M White, Anja Wittkowski, Shelley Appleton, Davina Sanders
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 11, p e23659 (2021)
BackgroundNew parents face increased risks of emotional distress and relationship dissatisfaction. Digital interventions increase support access, but few preventive programs are optimized for both parents. ObjectiveThis study aims to conduct the fir
Externí odkaz:
https://doaj.org/article/7ac844928e124c15b815ea14a0e2be7c
Publikováno v:
Work. 74:1015-1026
BACKGROUND: Vietnamese medical students believe becoming “strong” drinkers is important for their future career working as doctor. However, it is unclear if this is a temporary behaviour associated with life as a student, or a phenomenon associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902a9bd27dd088d3ca3e45c6755a8510
https://doi.org/10.3233/wor-210847
https://doi.org/10.3233/wor-210847