Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Katherine A Hoadley"'
Autor:
Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000975 (2020)
The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase and critical regulator of cell cycle progression. Despite its vital role, it has remained challenging to globally map APC/C substrates. By combining orthogonal features of kno
Externí odkaz:
https://doaj.org/article/5996078700384ca5bbd42dde1d166f90
Publikováno v:
Cancer Informatics, Vol 19 (2020)
We built a novel Bayesian hierarchical survival model based on the somatic mutation profile of patients across 50 genes and 27 cancer types. The pan-cancer quality allows for the model to “borrow” information across cancer types, motivated by the
Externí odkaz:
https://doaj.org/article/33f9892188bd431f9c20693a8c0f0878
Autor:
Vonn Walter, Xiaoying Yin, Matthew D Wilkerson, Christopher R Cabanski, Ni Zhao, Ying Du, Mei Kim Ang, Michele C Hayward, Ashley H Salazar, Katherine A Hoadley, Karen Fritchie, Charles J Sailey, Mark C Weissler, William W Shockley, Adam M Zanation, Trevor Hackman, Leigh B Thorne, William D Funkhouser, Kenneth L Muldrew, Andrew F Olshan, Scott H Randell, Fred A Wright, Carol G Shores, D Neil Hayes
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194674 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0056823.].
Externí odkaz:
https://doaj.org/article/22e39b3b45c1457597ac1145d7e7403a
Autor:
Katherine A Hoadley, Marni B Siegel, Krishna L Kanchi, Christopher A Miller, Li Ding, Wei Zhao, Xiaping He, Joel S Parker, Michael C Wendl, Robert S Fulton, Ryan T Demeter, Richard K Wilson, Lisa A Carey, Charles M Perou, Elaine R Mardis
Publikováno v:
PLoS Medicine, Vol 14, Iss 1, p e1002222 (2017)
[This corrects the article DOI: 10.1371/journal.pmed.1002174.].
Externí odkaz:
https://doaj.org/article/57d894c63b2c40bdab9c3849c78cfd31
Autor:
Katherine A Hoadley, Marni B Siegel, Krishna L Kanchi, Christopher A Miller, Li Ding, Wei Zhao, Xiaping He, Joel S Parker, Michael C Wendl, Robert S Fulton, Ryan T Demeter, Richard K Wilson, Lisa A Carey, Charles M Perou, Elaine R Mardis
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002174 (2016)
BACKGROUND:Metastasis is the main cause of cancer patient deaths and remains a poorly characterized process. It is still unclear when in tumor progression the ability to metastasize arises and whether this ability is inherent to the primary tumor or
Externí odkaz:
https://doaj.org/article/9e63c378b5cd4807a08a7b4d0841031e
Autor:
Hari Ilangovan, Prachi Kothiyal, Katherine A. Hoadley, Robin Elgart, Greg Eley, Parastou Eslami
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract NASA has employed high-throughput molecular assays to identify sub-cellular changes impacting human physiology during spaceflight. Machine learning (ML) methods hold the promise to improve our ability to identify important signals within hig
Externí odkaz:
https://doaj.org/article/39da41b7f01e4edd933e42973a4e7fff
Autor:
Vonn Walter, Xiaoying Yin, Matthew D Wilkerson, Christopher R Cabanski, Ni Zhao, Ying Du, Mei Kim Ang, Michele C Hayward, Ashley H Salazar, Katherine A Hoadley, Karen Fritchie, Charles J Sailey, Mark C Weissler, William W Shockley, Adam M Zanation, Trevor Hackman, Leigh B Thorne, William D Funkhouser, Kenneth L Muldrew, Andrew F Olshan, Scott H Randell, Fred A Wright, Carol G Shores, D Neil Hayes
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56823 (2013)
Head and neck squamous cell carcinoma (HNSCC) is a frequently fatal heterogeneous disease. Beyond the role of human papilloma virus (HPV), no validated molecular characterization of the disease has been established. Using an integrated genomic analys
Externí odkaz:
https://doaj.org/article/64d3a0789aae440ba7e75519ff9f9d12
Autor:
Mattia Rediti, Aranzazu Fernandez-Martinez, David Venet, Françoise Rothé, Katherine A. Hoadley, Joel S. Parker, Baljit Singh, Jordan D. Campbell, Karla V. Ballman, David W. Hillman, Eric P. Winer, Sarra El-Abed, Martine Piccart, Serena Di Cosimo, William Fraser Symmans, Ian E. Krop, Roberto Salgado, Sherene Loi, Lajos Pusztai, Charles M. Perou, Lisa A. Carey, Christos Sotiriou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The identification of prognostic markers in patients receiving neoadjuvant therapy is crucial for treatment optimization in HER2-positive breast cancer, with the immune microenvironment being a key factor. Here, we investigate the complexity
Externí odkaz:
https://doaj.org/article/14a09996519f49368d11a06978543f0a
Autor:
Yifeng Shi, Linnea T. Olsson, Katherine A. Hoadley, Benjamin C. Calhoun, J. S. Marron, Joseph Geradts, Marc Niethammer, Melissa A. Troester
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Approaches for rapidly identifying patients at high risk of early breast cancer recurrence are needed. Image-based methods for prescreening hematoxylin and eosin (H&E) stained tumor slides could offer temporal and financial efficiency. We ev
Externí odkaz:
https://doaj.org/article/bbe15f1a6a66435bbad73b6d57dbd0f7
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13073 (2010)
The transcription factor c-Myb has been well characterized as an oncogene in several human tumor types, and its expression in the hematopoietic stem/progenitor cell population is essential for proper hematopoiesis. However, the role of c-Myb in mammo
Externí odkaz:
https://doaj.org/article/8f3c676a591444ae87f8f5a4f9fc1152