Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katherine A Freitas"'
Autor:
Katalin Sandor, Peng Xu, Jing Huang, Steven A Feldman, Nikolaos Gkitsas, Crystal L Mackall, Bence Daniel, Dorota Klysz, Malek Bashti, Elena Sotillo, Ansuman T Satpathy, Carley Fowler, Meena Malipatlolla, Lucille Stuani, Katherine A Freitas, Stefanie Meier, Louai Labanieh, Amaury Leruste, Janette Mata-Alcazar, Vimal Keerthi, Justin A Guerrero, Chris Fisher, Sunny Patel, Kyle Asano, Shabnum Patel, Kara L Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ac586e86c0cd4992806758a3b9aa88b7
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/82e355df71634ede86eb223d9b31c03d
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Relationships between adult peers are central to the structure of social groups. In some species, selective preferences for specific peers provide a foundation for consistent group composition. These preferences may be shaped by affiliation toward fa
Externí odkaz:
https://doaj.org/article/cd8b2c27b0b042a7b16ac3795188fa96
Autor:
Crystal L. Mackall, Ravindra Majeti, Robbie G. Majzner, Ansuman T. Satpathy, Howard Y. Chang, Poul H. Sorensen, Wan-Jen Hong, Jie Liu, Htoo Zarni Oo, Mads Daugaard, Elena Sotillo, Amy Fan, Peng Xu, Kevin R. Parker, Katherine A. Freitas, Feifei Zhao, Rebecca M. Richards
Supplemental figures and legends in one document
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a648a9aba5801dbaef9a405c3d987d75
https://doi.org/10.1158/2643-3230.22543087
https://doi.org/10.1158/2643-3230.22543087
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Patrick J. Quinn, Maria C. Ramello, Meena Malipatlolla, Bence Daniel, Katalin Sandor, Dorota Klysz, Jeremy Bjelajac, Peng Xu, Kylie A. Burdsall, Victor Tieu, Vandon T. Duong, Micah G. Donovan, Evan W. Weber, Howard Y. Chang, Robbie G. Majzner, Joaquin M. Espinosa, Ansuman T. Satpathy, Crystal L. Mackall
Publikováno v:
Science (New York, N.Y.). 378(6620)
T cells are the major arm of the immune system responsible for controlling and regressing cancers. To identify genes limiting T cell function, we conducted genome-wide CRISPR knockout screens in human chimeric antigen receptor (CAR) T cells. Top hits
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Bence Daniel, Katalin Sandor, Dorota Klysz, Vandon T. Duong, Kylie Burdsall, Peng Xu, Meena Malipatlolla, Micah G. Donovan, Evan W. Weber, Robbie G. Majzner, Howard Y. Chang, Joaquin M. Espinosa, Ansuman T. Satpathy, Crystal L. Mackall
Adoptive T cell immune therapies mediate impressive clinical benefit in a fraction of patients, but anti-tumor effects are often limited by inadequate T cell potency. To identify genes limiting T cell effector function, we conducted genome-wide CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c4cb769a4ea3af40b5569af5a8250f
https://doi.org/10.1101/2022.09.02.506235
https://doi.org/10.1101/2022.09.02.506235
Autor:
Sean A. Yamada-Hunter, Johanna Theruvath, Molly T. Radosevich, Brianna J. McIntosh, Katherine A. Freitas, Naiara Martinez-Velez, Elena Sotillo, Amaury Leruste, Peng Xu, Moksha H. Desai, Bita Sahaf, Allison Banuelos, Savannah L. Wasserman, Irving L. Weissman, Jennifer R. Cochran, Crystal L. Mackall
Publikováno v:
Cancer Research. 83:5741-5741
Chimeric antigen receptor T (CAR T) cells are synthetically engineered to target specific tumor antigens. CD47 is a ubiquitous receptor that serves as a “don’t eat me” signal by binding to SIRPɑ on macrophages and is often over-expressed by ca
Autor:
Julia A. Belk, Winnie Yao, Nghi Ly, Katherine A. Freitas, Yan-Ting Chen, Quanming Shi, Alfredo M. Valencia, Eric Shifrut, Nupura Kale, Kathryn E. Yost, Connor V. Duffy, Madeline A. Hwee, Zhuang Miao, Alan Ashworth, Crystal L. Mackall, Alexander Marson, Julia Carnevale, Santosh A. Vardhana, Ansuman T. Satpathy
T cell exhaustion limits anti-tumor immunity, but the molecular determinants of this process remain poorly understood. Using a chronic antigen stimulation assay, we performed genome-wide CRISPR/Cas9 screens to systematically discover genetic regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f43c061aa8589a9656067aa9ec535a2a
https://doi.org/10.1101/2022.04.20.488974
https://doi.org/10.1101/2022.04.20.488974
Autor:
Julia A. Belk, Winnie Yao, Nghi Ly, Katherine A. Freitas, Yan-Ting Chen, Quanming Shi, Alfredo M. Valencia, Eric Shifrut, Nupura Kale, Kathryn E. Yost, Connor V. Duffy, Bence Daniel, Madeline A. Hwee, Zhuang Miao, Alan Ashworth, Crystal L. Mackall, Alexander Marson, Julia Carnevale, Santosh A. Vardhana, Ansuman T. Satpathy
Publikováno v:
Cancer cell. 40(7)
T cell exhaustion limits antitumor immunity, but the molecular determinants of this process remain poorly understood. Using a chronic stimulation assay, we performed genome-wide CRISPR-Cas9 screens to systematically discover regulators of T cell exha
Autor:
Katherine A. Freitas, Julia A. Belk, Elena Sotillo, Bence Daniel, Katalin Sandor, Dorota Klysz, Vandon T. Duong, Peng Xu, Meena Malipatlolla, Evan W. Weber, Robbie G. Majzner, Howard Y. Chang, Ansuman T. Satpathy, Crystal Mackall
Publikováno v:
Cancer Research. 82:2822-2822
Adoptive T cell immune therapies mediate impressive clinical benefit in a fraction of patients, but anti-tumor effects are often limited by inadequate T cell potency. To identify genes that limit T cell effector function, we conducted genome-wide CRI