Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Katherine A Dunn"'
Autor:
Marc A Benninga, Melvin B Heyman, Anthony Otley, Tim de Meij, Wouter J de Jonge, Charlotte M Verburgt, Katherine A Dunn, Sofia Verstraete, Withney Sunseri, Francisco Sylvester, Andre Comeau, Morgan Langille, Johan E Van Limbergen
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Introduction Early relapse in Crohn’s disease (CD) is associated with a more severe disease course. The microbiome plays a crucial role, yet strategies targeting the microbiome are underrepresented in current guidelines. We hypothesise that early m
Externí odkaz:
https://doaj.org/article/6e3aa02899e64cd4a0a780130aa08935
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 11, p e1003918 (2014)
Metagenomics yields enormous numbers of microbial sequences that can be assigned a metabolic function. Using such data to infer community-level metabolic divergence is hindered by the lack of a suitable statistical framework. Here, we describe a nove
Externí odkaz:
https://doaj.org/article/8d07235aaf994d53b63bec01ae872d17
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55816 (2013)
Adequate modeling of mitochondrial sequence evolution is an essential component of mitochondrial phylogenomics (comparative mitogenomics). There is wide recognition within the field that lineage-specific aspects of mitochondrial evolution should be a
Externí odkaz:
https://doaj.org/article/09e44274c55641a2a57749f1c5b0ca1b
Publikováno v:
Biochemistry and Biophysics Reports, Vol 31, Iss , Pp 101293- (2022)
Non-canonical forms of DNA are attracting increasing interest for applications in nanotechnology. It is frequently convenient to characterize DNA molecules using a label-free approach such as ultraviolet absorption spectroscopy. In this paper we pres
Externí odkaz:
https://doaj.org/article/fb174c1672d946e7b02e859cb3e9e649
Autor:
Katherine A. Dunn, Tamara MacDonald, Gloria J. Rodrigues, Zara Forbrigger, Joseph P. Bielawski, Morgan G.I. Langille, Johan Van Limbergen, Ketan Kulkarni
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Due to decreased immunity, both antibiotics and antifungals are regularly used in pediatric hematologic-cancer patients as a means to prevent severe infections and febrile neutropenia. The general effect of antibiotics on the human gut microbiome is
Externí odkaz:
https://doaj.org/article/072b5908a1e34fd1a59fc3df4b117cb2
Autor:
Ignazio Maria Viola, Brian Peterson, Gabriele Pisetta, Geethanjali Pavar, Hibbah Akhtar, Filippo Menoloascina, Enzo Mangano, Katherine E. Dunn, Roman Gabl, Alex Nila, Emanuela Molinari, Cathal Cummins, Gerard Thompson, Tsz-Yan Milly Lo, Fiona C. Denison, Paul Digard, Omair Malik, Mark J. G. Dunn, Catherine M. McDougall, Felicity V. Mehendale
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 26-35 (2021)
The SARS-CoV-2 virus is primarily transmitted through virus-laden fluid particles ejected from the mouth of infected people. Face covers can mitigate the risk of virus transmission but their outward effectiveness is not fully ascertained. Objective:
Externí odkaz:
https://doaj.org/article/2efcee0d775a4c3aba1b7dfa01747d71
Publikováno v:
Metabolic Engineering Communications, Vol 13, Iss , Pp e00175- (2021)
Phycocyanin (PC) is a soluble phycobiliprotein found within the light-harvesting phycobilisome complex of cyanobacteria and red algae, and is considered a high-value product due to its brilliant blue colour and fluorescent properties. However, commer
Externí odkaz:
https://doaj.org/article/4393a6a702e747c992c41e86cbcf360a
Autor:
Antoine Vallatos, James M. Maguire, Nikolas Pilavakis, Gabrielis Cerniauskas, Alexander Sturtivant, Alexander J. Speakman, Steve Gourlay, Scott Inglis, Graham McCall, Andrew Davie, Mike Boyd, Adriana A. S. Tavares, Connor Doherty, Sharen Roberts, Paul Aitken, Mark Mason, Scott Cummings, Andrew Mullen, Gordon Paterson, Matthew Proudfoot, Sean Brady, Steven Kesterton, Fraser Queen, Steve Fletcher, Andrew Sherlock, Katherine E. Dunn
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
During the COVID-19 pandemic, global health services have faced unprecedented demands. Many key workers in health and social care have experienced crippling shortages of personal protective equipment, and clinical engineers in hospitals have been sev
Externí odkaz:
https://doaj.org/article/a64c8405b525457296562f15cdf7f8c6
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-19 (2019)
Abstract Background An excess of nonsynonymous substitutions, over neutrality, is considered evidence of positive Darwinian selection. Inference for proteins often relies on estimation of the nonsynonymous to synonymous ratio (ω = d N/d S) within a
Externí odkaz:
https://doaj.org/article/4ddafe8db4774533866b45bc280b7d20
Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn’s disease
Autor:
Gavin M. Douglas, Richard Hansen, Casey M. A. Jones, Katherine A. Dunn, André M. Comeau, Joseph P. Bielawski, Rachel Tayler, Emad M. El-Omar, Richard K. Russell, Georgina L. Hold, Morgan G. I. Langille, Johan Van Limbergen
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Crohn’s disease (CD) has an unclear etiology, but there is growing evidence of a direct link with a dysbiotic microbiome. Many gut microbes have previously been associated with CD, but these have mainly been confounded with pati
Externí odkaz:
https://doaj.org/article/aa77a76475e046bb8f7f67e3fba09f9e