Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Katherine, Picard"'
Autor:
Rudy G. Jacquet, Fernando González Ibáñez, Katherine Picard, Lucy Funes, Mohammadparsa Khakpour, Gunnar K. Gouras, Marie-Ève Tremblay, Frederick R. Maxfield, Santiago Solé-Domènech
Publikováno v:
Cell Reports, Vol 43, Iss 12, Pp 115052- (2024)
Summary: How microglia digest Alzheimer’s fibrillar amyloid-beta (Aβ) plaques that are too large to be phagocytosed is not well understood. Here, we show that primary microglial cells create acidic extracellular compartments, lysosomal synapses, o
Externí odkaz:
https://doaj.org/article/4cc3189622f347658520a736aac382bc
Autor:
Micaël Carrier, Marie-Ève Robert, Marie-Kim St-Pierre, Fernando González Ibáñez, Elisa Gonçalves de Andrade, Audrée Laroche, Katherine Picard, Haley A. Vecchiarelli, Julie C. Savage, Éric Boilard, Michèle Desjardins, Marie-Ève Tremblay
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110037- (2024)
Summary: Although the roles of embryonic yolk sac-derived, resident microglia in neurodevelopment were extensively studied, the possible involvement of bone marrow-derived cells remains elusive. In this work, we used a fate-mapping strategy to select
Externí odkaz:
https://doaj.org/article/bf4a91ff75b7430f937daad11da42e1d
Autor:
Fanny Decoeur, Katherine Picard, Marie-Kim St-Pierre, Andrew D. Greenhalgh, Jean-Christophe Delpech, Alexandra Sere, Sophie Layé, Marie-Eve Tremblay, Agnès Nadjar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Over the last century, westernization of dietary habits has led to a dramatic reduction in dietary intake of n-3 polyunsaturated fatty acids (n-3 PUFAs). In particular, low maternal intake of n-3 PUFAs throughout gestation and lactation causes defect
Externí odkaz:
https://doaj.org/article/2c731041c18649f78b13f6764f064280
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The first electron microscope was constructed in 1931. Several decades later, techniques were developed to allow the first ultrastructural analysis of microglia by transmission electron microscopy (EM). In the 50 years that followed, important roles
Externí odkaz:
https://doaj.org/article/ae6693691e114edfa09ab822ec5af3c1
Autor:
Marie-Ève Tremblay, Olivier Pascual, Katherine Picard, Stefano Garofalo, Agnès Nadjar, Cristina Limatola
Publikováno v:
Comprehensive Physiology
Comprehensive Physiology, Wiley, 2020, 10 (2), pp.687-712. ⟨10.1002/cphy.c190022⟩
Comprehensive Physiology, Wiley, 2020, 10 (2), pp.687-712. ⟨10.1002/cphy.c190022⟩
Sleep is a naturally occurring physiological state that is required to sustain physical and mental health. Traditionally viewed as strictly regulated by top-down control mechanisms, sleep is now known to also originate locally. Glial cells are emergi
Autor:
Elisa Guma, Maude Bordeleau, Fernando González Ibáñez, Katherine Picard, Emily Snook, Gabriel Desrosiers-Grégoire, Shoshana Spring, Jason P. Lerch, Brian J. Nieman, Gabriel A. Devenyi, Marie-Eve Tremblay, M. Mallar Chakravarty
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Exposure to maternal immune activation (MIA) in utero is a risk factor for neurodevelopmental and psychiatric disorders. MIA-induced deficits in adolescent and adult offspring have been well characterized; however, less is known about the effects of
Autor:
Katherine Picard, Giorgio Corsi, Fanny Decoeur, Maria Amalia Di Castro, Maude Bordeleau, Marine Persillet, Sophie Layé, Cristina Limatola, Marie-Ève Tremblay, Agnès Nadjar
Sleep is a natural physiological state, tightly regulated through several neuroanatomical and neurochemical systems, which is essential to maintain physical and mental health. Recent studies revealed that the functions of microglia, the resident immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5332716fc0fff713884d69a62c8cb0c1
https://hal.science/hal-03891569
https://hal.science/hal-03891569
Autor:
Mohammadparsa, Khakpour, Fernando González, Ibáñez, Maude, Bordeleau, Katherine, Picard, Leo, Mckee-Reid, Benneth, Ben-Azu, Laura, Maggi, Marie-Ève, Tremblay
Publikováno v:
Micron. 161:103334
Microglia, the immune resident cells of the central nervous system (CNS), are now recognized as performing crucial roles for maintaining homeostasis and determining the outcomes of various pathological challenges across life. While brightfield micros
Autor:
Jason P. Lerch, Maude Bordeleau, Brian J. Nieman, Marie-Ève Tremblay, M. Mallar Chakravarty, Emily Snook, Gabriel A. Devenyi, Shoshana Spring, Desrosiers-Gregoire G, Elisa Guma, Katherine Picard, Gonzalez Ibanez F
Exposure to maternal immune activation (MIA) in utero is a risk factor for neurodevelopmental and psychiatric disorders. MIA-induced deficits in adolescent and adult offspring have been well characterized, however, less is known about the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e7c17c55d62e526c96f9671bca65a6
https://doi.org/10.1101/2021.07.14.452084
https://doi.org/10.1101/2021.07.14.452084
Autor:
Nathalie Vernoux, Xi Feng, Katherine Picard, Karen Krukowski, Amber Nolan, Susanna Rosi, Elma S. Frias, McKenna Becker, Marie-Ève Tremblay
Publikováno v:
Brain, behavior, and immunity. 98
Traumatic brain injury (TBI) is one of the leading causes of long-term neurological disability in the world. Currently, there are no therapeutics for treating the deleterious consequences of brain trauma; this is in part due to a lack of complete und