Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Katherine, Murphy"'
Autor:
Shane A Norris, Carl Lombard, Jean Claude Mutabazi, Katherine Murphy, Naomi Levitt, Christina Zarowsky, Tawanda Chivese, Lara R Fairall, Estelle Lambert, Lisa Jayne Ware, Mushi Matjila, Janetta Harbron, Lorrein Shamiso Muhwava
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion (47%) of the women are not awar
Externí odkaz:
https://doaj.org/article/d8b00bfa5ffb4d08acb7d9bc5e76d9f4
Autor:
Bojana Jovanović, Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine Murphy, Jayati Anand, Kodie Garza, Anushree Gulvady, Xintao Qiu, Nicholas W. Harper, Veerle W. Daniels, Huang Xiao-Yun, Jennifer Y. Ge, Maša Alečković, Jason Pyrdol, Kunihiko Hinohara, Shawn B. Egri, Malvina Papanastasiou, Raga Vadhi, Alba Font-Tello, Robert Witwicki, Guillermo Peluffo, Anne Trinh, Shaokun Shu, Benedetto Diciaccio, Muhammad B. Ekram, Ashim Subedee, Zachary T. Herbert, Kai W. Wucherpfennig, Anthony G. Letai, Jacob D. Jaffe, Piotr Sicinski, Myles Brown, Deborah Dillon, Henry W. Long, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113564- (2023)
Summary: Triple-negative breast cancer (TNBC) is a heterogeneous disease with limited treatment options. To characterize TNBC heterogeneity, we defined transcriptional, epigenetic, and metabolic subtypes and subtype-driving super-enhancers and transc
Externí odkaz:
https://doaj.org/article/5b7a46fb42fa443eac6a172b0b60048f
Autor:
Katherine Murphy, Jamie Berk, Lorrein Muhwava-Mbabala, Sharmilah Booley, Janetta Harbron, Lisa Ware, Shane Norris, Christina Zarowsky, Estelle V. Lambert, Naomi S. Levitt
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-19 (2023)
Abstract Background In South Africa, the prevalence of gestational diabetes (GDM) is growing, concomitant with the dramatically increasing prevalence of overweight/obesity among women. There is an urgent need to develop tailored interventions to supp
Externí odkaz:
https://doaj.org/article/efb6ae65cd364abea12b94098737d9d0
Autor:
Jacqueline M Martin-Kerry, Ian Kellar, Allan B Clark, Katherine Murphy, Sion Scott, Debi Bhattacharya, David Turner, Johanna Taylor, David Wright, Megan Pritchard, Miles Witham, David Phillip Alldred, Martyn Patel, Erika Sims, Antony Colles, Victoria L Keevil, Bethany Atkins, Amber Hammond
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Over 50% of older adults are prescribed a medicine where the risk of harm outweighs the chances of benefit. During a hospital admission, older adults and carers expect medicines to be reviewed for appropriateness and any inappropriate me
Externí odkaz:
https://doaj.org/article/9048d5a6c36d41ba9f629f7c15a3d660
Autor:
Myrna van Pinxteren, Nonzuzo Mbokazi, Katherine Murphy, Frances S. Mair, Carl May, Naomi Levitt
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundPeople living with multimorbidity in low-and middle-income countries (LMICs) experience a high workload trying to meet the demands of self-management. In an unequal society like South Africa, many people face continuous economic uncertainty
Externí odkaz:
https://doaj.org/article/7b92473acb4d496cb5f0a06fd984433b
Autor:
Jean Claude Mutabazi, Mahmoud Werfalli, Angeli Rawat, Ezekiel Musa, Tawanda Chivese, Shane Norris, Katherine Murphy, Helen Trottier, Naomi Levitt, Christina Zarowsky
Publikováno v:
International Journal of Integrated Care, Vol 22, Iss 3 (2022)
Introduction: Many adults diagnosed with gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) also have other known or unknown comorbid conditions. The rising prevalence of GDM and T2DM within a broader context of multimorbidity ca
Externí odkaz:
https://doaj.org/article/15ddb756b3d846c9969d6cbb775ec348
Autor:
Jean Claude Mutabazi, Pascal Roland Enok Bonong, Helen Trottier, Lisa Jayne Ware, Shane Norris, Katherine Murphy, Naomi Levitt, Christina Zarowsky
Publikováno v:
International Journal of Integrated Care, Vol 22, Iss 3 (2022)
Background: Despite high gestational diabetes mellitus (GDM) prevalence in South Africa (9.1% in 2018), its screening and management are not well integrated into routine primary health care and poorly linked to post-GDM prevention of type 2 diabetes
Externí odkaz:
https://doaj.org/article/a2ad440ac50a4aa997f932b0c73cde8a
Publikováno v:
BMC Women's Health, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The diagnosis of gestational diabetes mellitus (GDM) may affect women’s mental wellbeing, functioning and quality of life, with potentially negative effects on treatment adherence. Identifying and addressing the psychological an
Externí odkaz:
https://doaj.org/article/28263e3d4df246239e1272c40b25814e
Autor:
Jean Claude Mutabazi, Corie Gray, Lorrein Muhwava, Helen Trottier, Lisa Jayne Ware, Shane Norris, Katherine Murphy, Naomi Levitt, Christina Zarowsky
Publikováno v:
BMC Health Services Research, Vol 20, Iss 1, Pp 1-18 (2020)
Abstract Background Integrating Prevention of Mother-to-Child Transmission (PMTCT) programmes into routine health services under complex socio-political and health system conditions is a priority and a challenge. The successful rollout of PMTCT in su
Externí odkaz:
https://doaj.org/article/9c12b529a5ac453783f80a57150aa9c8
Autor:
Jennifer Y. Ge, Shaokun Shu, Mijung Kwon, Bojana Jovanović, Katherine Murphy, Anushree Gulvady, Anne Fassl, Anne Trinh, Yanan Kuang, Grace A. Heavey, Adrienne Luoma, Cloud Paweletz, Aaron R. Thorner, Kai W. Wucherpfennig, Jun Qi, Myles Brown, Piotr Sicinski, Thomas O. McDonald, David Pellman, Franziska Michor, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Effective combination therapies to improve the efficacy of BET inhibitors are currently under investigation. Here, the authors examine palbociclib and paclitaxel as two promising candidates for combination therapies with BET inhibition in breast canc
Externí odkaz:
https://doaj.org/article/c6750e9707894301940edb49bbf81051