Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Katherine, Karakasis"'
Autor:
Lawrence Kasherman, Jeffrey Doi, Katherine Karakasis, Jeffrey Schiff, Abhijat Kitchlu, Stephanie Lheureux, Amit M. Oza
Publikováno v:
Current Oncology, Vol 28, Iss 1, Pp 661-670 (2021)
Solid organ transplant recipients on long-term immunosuppressive medication are at increased risk of developing malignancy, and treatment of advanced cancers with angiogenesis inhibitors in this context has not been widely studied. We present a case
Externí odkaz:
https://doaj.org/article/cd2a6aa6e8f14cbca3e659ed04a60424
Autor:
Amit M Oza, Qin Liu, Ainhoa Madariaga, Lawrence Kasherman, Lisa Wang, Michelle McMullen, Katherine Karakasis, Luisa Bonilla, Shiru (Lucy) Liu, Rouhi Fazelzad, Ann M Heesters
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Objectives In response to the COVID-19 pandemic there have been significant developments in research, its conduct and the supporting ethical framework. While many protocols have been delayed, halted or modified, other research efforts have been accel
Externí odkaz:
https://doaj.org/article/e3c91c157690489db6792a5db944016d
Autor:
Lawrence Kasherman, Swati Garg, Nairi Tchrakian, Blaise Clarke, Katherine Karakasis, Raymond H. Kim, Tracy L. Stockley, Neesha Dhani, Amit M. Oza, Stephanie Lheureux
Publikováno v:
Gynecologic Oncology Reports, Vol 36, Iss , Pp 100729- (2021)
Externí odkaz:
https://doaj.org/article/22d1f54291334466ab285585d51a10ad
Autor:
S. Y. Cindy Yang, Stephanie Lheureux, Katherine Karakasis, Julia V. Burnier, Jeffery P. Bruce, Derek L. Clouthier, Arnavaz Danesh, Rene Quevedo, Mark Dowar, Youstina Hanna, Tiantian Li, Lin Lu, Wei Xu, Blaise A. Clarke, Pamela S. Ohashi, Patricia A. Shaw, Trevor J. Pugh, Amit M. Oza
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-17 (2018)
Abstract Background Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experie
Externí odkaz:
https://doaj.org/article/442a3e5a464143828f9cb795c9072289
Autor:
Ainhoa Madariaga, Sandra A. Mitchell, Tyler Pittman, Lisa Wang, Valerie Bowering, Nisan Kavak, Judy Quintos, Karen Chang, Janelle Ramsahai, Katherine Karakasis, Stephen A. Welch, Neesha C. Dhani, Stephanie Lheureux, Amit M. Oza
Publikováno v:
Gynecologic Oncology. 167:226-233
A double-blind, randomized, placebo-controlled, phase 2 trial assessed gemcitabine in combination with the wee1 inhibitor adavosertib or placebo in platinum resistant or refractory high grade serous ovarian cancer (HGSOC), demonstrating improved prog
Autor:
Amit M. Oza, Tony W. Ho, J. Carl Barrett, Jonathan Ledermann, Jane D. Robertson, Mark J. O'Connor, C. Blake Gilks, Julia V. Burnier, Katherine Karakasis, Tony Panzarella, Ursula Matulonis, Claire Scott, Elise C. Kohn, David Bowtell, Charlie Gourley, Stan Kaye, Jerry S. Lanchbury, Kirsten M. Timms, Darren R. Hodgson, Sarah Runswick, Brian A. Dougherty, Zhongwu Lai, Stephanie Lheureux
Purpose: Maintenance therapy with olaparib has improved progression-free survival in women with high-grade serous ovarian cancer (HGSOC), particularly those harboring BRCA1/2 mutations. The objective of this study was to characterize long-term (LT) v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f3cf8b7ca62d919c2266027f7eb78d
https://doi.org/10.1158/1078-0432.c.6527036.v1
https://doi.org/10.1158/1078-0432.c.6527036.v1
Autor:
Amit M. Oza, Trevor J. Pugh, Zhihui (Amy) Liu, Yeh Chen Lee, Lorena Fariñas-Madrid, Tiantiam Li, Stephanie Pedersen, Iulia Cirlan, Katherine Karakasis, Marsela Braunstein, Qian Tan, Sarah Accardi, Justin White, Valerie Bowering, Neesha C. Dhani, Ainhoa Madariaga, Jeffrey P. Bruce, Swati Garg, Ana Oaknin, Stephanie Lheureux
Purpose:PARP inhibitors (PARPi) are standard-of-care therapy for high-grade serous ovarian cancer (HGSOC). We investigated combining cediranib (antiangiogenic) with olaparib (PARPi) at emergence of PARPi resistance.Patients and Methods:The proof-of-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6b12c6b527a49a4e3a78faae4c695b
https://doi.org/10.1158/1078-0432.c.6529832.v1
https://doi.org/10.1158/1078-0432.c.6529832.v1
Autor:
Amit M. Oza, Trevor J. Pugh, Zhihui (Amy) Liu, Yeh Chen Lee, Lorena Fariñas-Madrid, Tiantiam Li, Stephanie Pedersen, Iulia Cirlan, Katherine Karakasis, Marsela Braunstein, Qian Tan, Sarah Accardi, Justin White, Valerie Bowering, Neesha C. Dhani, Ainhoa Madariaga, Jeffrey P. Bruce, Swati Garg, Ana Oaknin, Stephanie Lheureux
Supplementary figures S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d679bdd491ba0f821924302bcc5dcb5d
https://doi.org/10.1158/1078-0432.22478051
https://doi.org/10.1158/1078-0432.22478051
Autor:
Amit M. Oza, Tony W. Ho, J. Carl Barrett, Jonathan Ledermann, Jane D. Robertson, Mark J. O'Connor, C. Blake Gilks, Julia V. Burnier, Katherine Karakasis, Tony Panzarella, Ursula Matulonis, Claire Scott, Elise C. Kohn, David Bowtell, Charlie Gourley, Stan Kaye, Jerry S. Lanchbury, Kirsten M. Timms, Darren R. Hodgson, Sarah Runswick, Brian A. Dougherty, Zhongwu Lai, Stephanie Lheureux
Supplementary Figure 1. Mutational analysis of TP53 in the olaparib arm. (A) Analysis of TP53 mutation type. (B) BRCA1 and BRCA2 mutation type Supplementary Table 1. Platinum sensitivity and outcome on olaparib maintenance treatment. Supplementary Ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dce4e67ff8abc1435358f47967de32e
https://doi.org/10.1158/1078-0432.22468700.v1
https://doi.org/10.1158/1078-0432.22468700.v1
Autor:
Nazlin Jivraj, Yeh Chen Lee, Lisa Tinker, Valerie Bowering, Sarah E. Ferguson, Jennifer Croke, Katherine Karakasis, Tanya Chawla, Jenny Lau, Pamela Ng, Preeti Dhar, Eran Shlomovitz, Sarah Buchanan, Neesha Dhani, Amit M. Oza, Terri Stuart-McEwan, Stephanie Lheureux
Publikováno v:
Journal of nursing care quality. 38(1)
Malignant bowel obstruction (MBO) in patients with advanced gynecologic cancer (GyCa) can negatively impact clinical outcomes and quality of life. Oncology nurses can support these patients with adequate tools/processes.Patients with GyCa with/at ris