Výsledky vyhledávání - "Katherine, Huang"

Akademický článek

Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank

Autor: Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher, Christopher W. Armstrong

Publikováno v: Communications Medicine, Vol 4, Iss 1, Pp 1-14 (2024)

Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and presence of comorbid conditions. ME/CFS patients often present with multiple health i

Externí odkaz: https://doaj.org/article/5fab4358b9b24c208c476f3b0b588a37

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Akademický článek

Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME): protocol paper for a multidisciplinary, observational study of clinical and biological markers of paediatric myalgic encephalomyelitis/chronic fatigue syndrome in Australian adolescents aged 12–19 years

Autor: Adam Scheinberg, Natalie Thomas, Katherine Huang, Paul R Gooley, Elisha K Josev, Tracey Chau, Darcy Tantanis, Sarah J Knight, Christopher W Armstrong

Publikováno v: BMJ Open, Vol 14, Iss 12 (2024)

Introduction Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition that can affect adolescents during a vulnerable period of development. The underlying biological mechanisms for ME/CFS remain unclear and have rarely be

Externí odkaz: https://doaj.org/article/0ff6ae6d6228438f84932d9dfedae069

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Akademický článek

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

Autor: Sean A. Misek, Aaron Fultineer, Jeremie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G. Doench, David E. Root, James M. McFarland, Rameen Beroukhim, Jesse S. Boehm

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Reducing disparities is vital for equitable access to precision treatments in cancer. Socioenvironmental factors are a major driver of disparities, but differences in genetic variation likely also contribute. The impact of genetic ancestry o

Externí odkaz: https://doaj.org/article/f5fc9a4be68842a79c2275a29dc90764

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Akademický článek

Canada’s Geothermal Energy Update in 2023

Publikováno v: Energies, Vol 17, Iss 8, p 1807 (2024)

Geothermal energy exploration, development, and research have been ongoing in Canada for several decades. The country’s cold climate and the push to develop renewable energy sources have driven interest in geothermal energy. Despite this drive, reg

Externí odkaz: https://doaj.org/article/5e1b0ac184904a30bfa16df79904b73f

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Akademický článek

An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

Autor: Juan Alcantara, Robyn Stix, Katherine Huang, Acadia Connor, Ray East, Valeria Jaramillo-Martinez, Elliott J. Stollar, K. Aurelia Ball

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain. T

Externí odkaz: https://doaj.org/article/f1791d82aafe4d9dbee25ef021463a37

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Akademický článek

Systematic Review of NMR-Based Metabolomics Practices in Human Disease Research

Autor: Katherine Huang, Natalie Thomas, Paul R. Gooley, Christopher W. Armstrong

Publikováno v: Metabolites, Vol 12, Iss 10, p 963 (2022)

Nuclear magnetic resonance (NMR) spectroscopy is one of the principal analytical techniques for metabolomics. It has the advantages of minimal sample preparation and high reproducibility, making it an ideal technique for generating large amounts of m

Externí odkaz: https://doaj.org/article/761d0d5c3f9a4ed6a8d6dbbc27540ac0

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Akademický článek

Bugs and Brains, the Gut and Mental Health Study: a mixed-methods study investigating microbiota composition and function in anxiety, depression and irritable bowel syndrome

Autor: Carra A Simpson, Orli S Schwartz, Djamila Eliby, Catherine A Butler, Katherine Huang

Publikováno v: BMJ Open, Vol 11, Iss 3 (2021)

Introduction Research has highlighted relationships between the micro-organisms that inhabit our gastrointestinal tract (oral and gut microbiota) with host mood and gastrointestinal functioning. Mental health disorders and functional gastrointestinal

Externí odkaz: https://doaj.org/article/84e398a4ea0c434caba52bfc0c448188

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