Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Katherine, Chan"'
Autor:
Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe, Reuben Samson, Aaron Au, Yukti Khanna, Zetao Liu, Ran Cheng, Kamaldeep Aulakh, Jiarun Wei, Adrian Granda Farias, Taylor Reilly, Saba Birkadze, Andrea Habsid, Kevin R. Brown, Katherine Chan, Patricia Mero, Jie Qi Huang, Maximilian Billmann, Mahfuzur Rahman, Chad Myers, Brenda J. Andrews, Ji-Young Youn, Christopher M. Yip, Daniela Rotin, W. Brent Derry, Julie D. Forman-Kay, Alan M. Moses, Iva Pritišanac, Anne-Claude Gingras, Jason Moffat
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114417- (2024)
Summary: The ability to sense and respond to osmotic fluctuations is critical for the maintenance of cellular integrity. We used gene co-essentiality analysis to identify an unappreciated relationship between TSC22D2, WNK1, and NRBP1 in regulating ce
Externí odkaz:
https://doaj.org/article/6cfa9d4fad5f4dfe962cefa4d0b2f79f
Autor:
Kevin Lin, Ya-Chu Chang, Maximilian Billmann, Henry N. Ward, Khoi Le, Arshia Z. Hassan, Urvi Bhojoo, Katherine Chan, Michael Costanzo, Jason Moffat, Charles Boone, Anja-Katrin Bielinsky, Chad L. Myers
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Current approaches to define chemical-genetic interactions (CGIs) in human cell lines are resource-intensive. We designed a scalable chemical-genetic screening platform by generating a DNA damage response (DDR)-focused custom sgRNA library t
Externí odkaz:
https://doaj.org/article/3b9ce5f7b8554685b2e0afb2fc4f3cce
Autor:
Sylvia Varland, Rui Duarte Silva, Ine Kjosås, Alexandra Faustino, Annelies Bogaert, Maximilian Billmann, Hadi Boukhatmi, Barbara Kellen, Michael Costanzo, Adrian Drazic, Camilla Osberg, Katherine Chan, Xiang Zhang, Amy Hin Yan Tong, Simonetta Andreazza, Juliette J. Lee, Lyudmila Nedyalkova, Matej Ušaj, Alexander J. Whitworth, Brenda J. Andrews, Jason Moffat, Chad L. Myers, Kris Gevaert, Charles Boone, Rui Gonçalo Martinho, Thomas Arnesen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-27 (2023)
Abstract Most eukaryotic proteins are N-terminally acetylated, but the functional impact on a global scale has remained obscure. Using genome-wide CRISPR knockout screens in human cells, we reveal a strong genetic dependency between a major N-termina
Externí odkaz:
https://doaj.org/article/d00c6a73922e4ae69223e5ddad630fd5
Autor:
Natasha L. Benn, Hope Jervis-Rademeyer, Kayla Benson, Katherine Chan, Jae W. Lee, Elizabeth L. Inness, Dalton L. Wolfe, Milad Alizadeh-Meghrazi, Kei Masani, Kristin E. Musselman
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Most individuals living with spinal cord injuries/diseases (SCI/D) or stroke experience at least one fall each year; hence, the development of interventions and technologies that target balance control is needed. The purpose of th
Externí odkaz:
https://doaj.org/article/bdf18fd8cc234e1db0a43c9230aadf81
Autor:
Gayle Ross, Peter Stewart, George Mensing, Melanie Chin, Haley Howell, Andeleeb Dahy, Katherine Chan, Pankaj Daga, Heidi Mangus, Will Savage
Publikováno v:
HemaSphere, Vol 7, p e507380c (2023)
Externí odkaz:
https://doaj.org/article/4ee420a934c24a0da0242db71cc74193
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background/objective To explore parents’ perceptions of an upper extremity (UE) intervention using functional electrical stimulation (FES) for young children with hemiparesis. Methods Parents of children aged 3–6 years with a history of
Externí odkaz:
https://doaj.org/article/e33d8f99b8af435187f8ee86b2f94add
Autor:
Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kevin R. Brown, Henry Ward, Maximilian Billmann, Kamaldeep Aulakh, Audrey Astori, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Shuye Pu, Andrea Habsid, Amy Hin Yan Tong, Natasha Christie-Holmes, Patrick Budylowski, Ayoob Ghalami, Samira Mubareka, Finlay Maguire, Arinjay Banerjee, Karen L. Mossman, Jack Greenblatt, Scott D. Gray-Owen, Brian Raught, Benjamin J. Blencowe, Mikko Taipale, Chad Myers, Jason Moffat
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12744- (2023)
SARS-CoV-2 depends on host cell components for infection and replication. Identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection and replication. If druggable, host factor dependencies ma
Externí odkaz:
https://doaj.org/article/1fc0974096af4f23af93d99b3d0085a0
Autor:
Anita Kaiser, MSc, Katherine Chan, MSc, Maureen Pakosh, MISt, Shane McCullum, Chris Rice, José Zariffa, PhD, Kristin E. Musselman, PhD
Publikováno v:
Archives of Rehabilitation Research and Clinical Translation, Vol 4, Iss 4, Pp 100218- (2022)
Objective: To identify the characteristics of activity-based therapy (ABT) that individuals with spinal cord injury and disease (SCI/D) participate in across the continuum of care. Data Sources: A search of 8 databases was conducted from inception to
Externí odkaz:
https://doaj.org/article/902958328ae6433db0144671e50d29c8
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Previous findings indicate that co-contractions of plantarflexors and dorsiflexors during quiet standing increase the ankle mechanical joint stiffness, resulting in increased postural sway. Balance impairments in individuals with incomplete
Externí odkaz:
https://doaj.org/article/6fb84632dbb548b38ba3ab3d4bc122e0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/23487c160d8f41db92befe460c6249b3