Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Katherine, Beck"'
Autor:
Katherine Beck, Atheeshaan Arumuham, Mattia Veronese, Barbara Santangelo, Colm J. McGinnity, Joel Dunn, Robert A. McCutcheon, Stephen J. Kaar, Nisha Singh, Toby Pillinger, Faith Borgan, James Stone, Sameer Jauhar, Teresa Sementa, Federico Turkheimer, Alexander Hammers, Oliver D. Howes
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract N-methyl-D-aspartate receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. To address this, we studied 40 volunteers (21 patients with first-episode psychosis and 19 matched health
Externí odkaz:
https://doaj.org/article/01e5daca97374a1c9b30a252f899148c
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal (2022)
Barium ions block potassium leak channels that contribute to the resting membrane potential in most animal cells (Armstrong and Taylor, 1980). Here we examine the impact of barium on the resting membrane potential of crayfish superficial flexor muscl
Externí odkaz:
https://doaj.org/article/27c834133ae944d5a98af2aa845953cf
Autor:
Katherine, Beck, Atheeshaan, Arumuham, Stefan, Brugger, Robert A, McCutcheon, Mattia, Veronese, Barbara, Santangelo, Colm J, McGinnity, Joel, Dunn, Stephen, Kaar, Nisha, Singh, Toby, Pillinger, Faith, Borgan, Teresa, Sementa, Radhouene, Neji, Sameer, Jauhar, Franklin, Aigbirhio, Istvan, Boros, Federico, Turkheimer, Alexander, Hammers, David, Lythgoe, James, Stone, Oliver D, Howes
Publikováno v:
Journal of psychopharmacology (Oxford, England). 36(9)
Evidence from post-mortem studies and in vivo imaging studies suggests there may be reducedIn this study, we investigated the relationship between hippocampal NMDAR and striatal glutamate using simultaneous positron emission tomography-magnetic reson
Autor:
Katherine Beck, Atheeshaan Arumuham, Stefan Brugger, Robert A McCutcheon, Mattia Veronese, Barbara Santangelo, Colm J McGinnity, Joel Dunn, Stephen Kaar, Nisha Singh, Toby Pillinger, Faith Borgan, Teresa Sementa, Radhouene Neji, Sameer Jauhar, Franklin Aigbirhio, Istvan Boros, Federico Turkheimer, Alexander Hammers, David Lythgoe, James Stone, Oliver D Howes
Publikováno v:
Beck, K, Arumuham, A, Brugger, S, McCutcheon, R A, Veronese, M, Santangelo, B, McGinnity, C J, Dunn, J, Kaar, S, Singh, N, Pillinger, T, Borgan, F, Sementa, T, Neji, R, Jauhar, S, Aigbirhio, F, Boros, I, Turkheimer, F, Hammers, A, Lythgoe, D, Stone, J & Howes, O D 2022, ' The association between N-methyl-d-aspartate receptor availability and glutamate levels : A multi-modal PET-MR brain imaging study in first-episode psychosis and healthy controls ', Journal of psychopharmacology (Oxford, England), vol. 36, no. 9, pp. 1051-1060 . https://doi.org/10.1177/02698811221099643
Background: Evidence from post-mortem studies and in vivo imaging studies suggests there may be reduced N-methyl-d-aspartate receptor (NMDAR) levels in the hippocampus in patients with schizophrenia. Other studies have reported increased glutamate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6447a0ee7a2d68ead15c25c3f70e79e7
https://kclpure.kcl.ac.uk/ws/files/184987017/The_association_between_BECK_Publishedonline19September2022_GREEN_AAM.pdf
https://kclpure.kcl.ac.uk/ws/files/184987017/The_association_between_BECK_Publishedonline19September2022_GREEN_AAM.pdf
Autor:
Matthew M, Nour, Katherine, Beck, Yunzhe, Liu, Atheeshaan, Arumuham, Mattia, Veronese, Oliver D, Howes, Raymond J, Dolan
Publikováno v:
Schizophrenia bulletin open. 3(1)
Hippocampal replay and associated high-frequency ripple oscillations are among the best-characterized phenomena in resting brain activity. Replay/ripples support memory consolidation and relational inference, and are regulated byHere, we avail of a u
Autor:
Binil Eldhose, Katherine Beck, Cyrus Eghtedari, Gartrell C. Bowling, Mallesh Pandrala, Sanjay V. Malhotra, Xiaofeng A. Su, Albert Dobi
Publikováno v:
Cancer Research. 83:4868-4868
Introduction: Prostate cancer (PCa) is the second leading cause of cancer deaths among men in the United States. Approximately 50% of patients with PCa harbor an oncogenic TMPRRS2- ERG gene fusion in their primary tumor and 35% of patients with metas
Autor:
Emma Butler, Toby Pillinger, Kirsten Brown, Faith Borgan, Alice Bowen, Katherine Beck, Enrico D'Ambrosio, Lisa Donaldson, Sameer Jauhar, Stephen Kaar, Tiago Reis Marques, Robert A. McCutcheon, Maria Rogdaki, Fiona Gaughran, James MacCabe, Rosalind Ramsay, David Taylor, Paul McCrone, Alice Egerton, Oliver D. Howes
Publikováno v:
The British journal of psychiatry : the journal of mental science. 221(6)
BackgroundClozapine is the only drug licensed for treatment-resistant schizophrenia (TRS) but the real-world clinical and cost-effectiveness of community initiation of clozapine is unclear.AimsThe aim was to assess the feasibility and cost-effectiven
Autor:
Robert A. McCutcheon, Oliver D. Howes, Daniël Kleinloog, Faith Borgan, Katherine Beck, Rajiv Radhakrishnan, Suhas Ganesh, Guy Hindley, Deepak Cyril D'Souza, Cedric E. Ginestet
Publikováno v:
The Lancet Psychiatry. 7:344-353
Background Approximately 188 million people use cannabis yearly worldwide, and it has recently been legalised in 11 US states, Canada, and Uruguay for recreational use. The potential for increased cannabis use highlights the need to better understand
Autor:
Oliver D. Howes, Toby Pillinger, Andrea Cipriani, Orestis Efthimiou, Yuya Mizuno, Guy Frederick Lanyon Hindley, Luke Vano, Sridhar Natesan, Robert A. McCutcheon, Atheeshaan Arumuham, Katherine Beck
Publikováno v:
Pillinger, Toby; McCutcheon, Robert A; Vano, Luke; Mizuno, Yuya; Arumuham, Atheeshaan; Hindley, Guy; Beck, Katherine; Natesan, Sridhar; Efthimiou, Orestis; Cipriani, Andrea; Howes, Oliver D (2020). Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. The Lancet. Psychiatry, 7(1), pp. 64-77. Elsevier 10.1016/S2215-0366(19)30416-X
Pillinger, T, McCutcheon, R A, Vano, L, Mizuno, Y, Arumuham, A, Hindley, G, Beck, K, Natesan, S, Efthimiou, O, Cipriani, A & Howes, O D 2020, ' Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology : a systematic review and network meta-analysis ', The Lancet Psychiatry, vol. 7, no. 1, pp. 64-77 . https://doi.org/10.1016/S2215-0366(19)30416-X
Pillinger, T, McCutcheon, R A, Vano, L, Mizuno, Y, Arumuham, A, Hindley, G, Beck, K, Natesan, S, Efthimiou, O, Cipriani, A & Howes, O D 2020, ' Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology : a systematic review and network meta-analysis ', The Lancet Psychiatry, vol. 7, no. 1, pp. 64-77 . https://doi.org/10.1016/S2215-0366(19)30416-X
Background: Antipsychotic treatment is associated with metabolic disturbance. However, the degree to which metabolic alterations occur in treatment with different antipsychotics is unclear. Predictors of metabolic dysregulation are poorly understood
Autor:
Sangho Shin, Wi Hoon Jung, Robert McCutcheon, Mattia Veronese, Katherine Beck, Jae Sung Lee, Yun-Sang Lee, Oliver D. Howes, Euitae Kim, Jun Soo Kwon
Publikováno v:
Shin, S, Jung, W H, McCutcheon, R, Veronese, M, Beck, K, Lee, J S, Lee, Y S, Howes, O D, Kim, E & Kwon, J S 2022, ' The Relationship Between Frontostriatal Connectivity and Striatal Dopamine Function in Schizophrenia : An 18 F-DOPA PET and Diffusion Tensor Imaging Study in Treatment Responsive and Resistant Patients ', Psychiatry Investigation, vol. 19, no. 7, pp. 570-579 . https://doi.org/10.30773/pi.2022.0033
Objective Striatal dopamine dysfunction caused by cortical abnormalities is a leading hypothesis of schizophrenia. Although prefrontal cortical pathology is negatively correlated with striatal dopamine synthesis, the relationship between structural f