Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katheen M Ogilvie"'
Autor:
Anne Reifel-Miller, Katheen M Ogilvie, Christopher M. Mapes, Mark D. Leibowitz, Donald S. Karanewsky, Marcus F. Boehm, Jyun-Hung Chen, Anthony W. Thompson, Robert Ardecky, Pierre-Yves Michellys, John S. Tyhonas, Sha Liu, Nathan Yumibe, Deepa Rungta, Timothy Alan Grese, Dale A. Mais
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(22)
New RXR-selective modulators possessing a 6-fluoro trienoic acid moiety (6Z olefin) or a fluorinated/heterocyclic-substituted benzene core ring, were synthesized in an expedient and selective way. A subset of these compounds was evaluated for their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c260917cabd1b5b16aa3a9de63ed3bc
https://pubmed.ncbi.nlm.nih.gov/14592510
https://pubmed.ncbi.nlm.nih.gov/14592510
Autor:
Pierre-Yves Michellys, Mark D Leibowitz, Marcus F. Boehm, Jennifer D'Arrigo, Anne Reifel-Miller, Christopher M. Mapes, Robert J. Ardecky, D.A. Mais, Chahrzad Montrose-Rafizadeh, Sha Liu, Donald S. Karanewsky, John S. Tyhonas, Deepa Rungta, Timothy Alan Grese, Jyun-Hung Chen, Anthony W. Thompson, Katheen M Ogilvie
Publikováno v:
Journal of medicinal chemistry. 46(19)
Retinoid X receptor:peroxisome proliferative-activated receptor (RXR:PPAR) heterodimers play a critical role in the regulation of glucose (RXR/PPARgamma) and lipid metabolism (RXR/PPARalpha). Previously, we described a concise structure-activity rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eea8b4fbbc3b55ea587ba9594c00647
https://pubmed.ncbi.nlm.nih.gov/12954061
https://pubmed.ncbi.nlm.nih.gov/12954061
Autor:
Christopher M. Mapes, Anthony W. Thompson, K Klausing, Anne Reifel-Miller, Robert Ardecky, Donald S. Karanewsky, Deepa Rungta, John S. Tyhonas, Mark D. Leibowitz, Timothy Alan Grese, Sha Liu, D.A. Mais, Margaret M. Faul, Garret J. Etgen, K B Marschke, A L Faulkner, Marcus F. Boehm, Jyun-Hung Chen, Pierre-Yves Michellys, Katheen M Ogilvie, D L Crombie, Richard A. Heyman
Publikováno v:
Journal of medicinal chemistry. 46(13)
Previous data have shown that RXR-selective agonists (e.g., 3 and 4) are insulin sensitizers in rodent models of non-insulin-dependent diabetes mellitus (NIDDM). Unfortunately, they also produce dramatic increases in triglycerides and profound suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0a076facd0899614067ed9d41533cd
https://pubmed.ncbi.nlm.nih.gov/12801232
https://pubmed.ncbi.nlm.nih.gov/12801232